negative regulation of immune response Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. (Gene Ontology, GO_0050777)
External Link http://amigo.geneontology.org/amigo/term/GO:0050777
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Genes

71 genes participating in the negative regulation of immune response biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACOD1 aconitate decarboxylase 1
ALOX15 arachidonate 15-lipoxygenase
AMBP alpha-1-microglobulin/bikunin precursor
ATG12 autophagy related 12
ATG5 autophagy related 5
AURKB aurora kinase B
BANF1 barrier to autointegration factor 1
C9ORF72 chromosome 9 open reading frame 72
CACTIN cactin, spliceosome C complex subunit
CCR2 chemokine (C-C motif) receptor 2
CD300A CD300a molecule
CEP63 centrosomal protein 63kDa
CLEC12A C-type lectin domain family 12, member A
COL3A1 collagen, type III, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DTX4 deltex 4, E3 ubiquitin ligase
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FER fer (fps/fes related) tyrosine kinase
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXP3 forkhead box P3
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
GNAS GNAS complex locus
HAVCR2 hepatitis A virus cellular receptor 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
IFI16 interferon, gamma-inducible protein 16
IFNL1 interferon, lambda 1
IL27RA interleukin 27 receptor, alpha
IRAK3 interleukin-1 receptor-associated kinase 3
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LONP1 lon peptidase 1, mitochondrial
LYAR Ly1 antibody reactive
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK14 mitogen-activated protein kinase 14
MKRN2 makorin ring finger protein 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NLRC3 NLR family, CARD domain containing 3
NLRP4 NLR family, pyrin domain containing 4
NMI N-myc (and STAT) interactor
PARP1 poly (ADP-ribose) polymerase 1
PDCD1 programmed cell death 1
PLCG1 phospholipase C, gamma 1
PLK2 polo-like kinase 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RC3H1 ring finger and CCCH-type domains 1
REXO2 RNA exonuclease 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SPI1 Spi-1 proto-oncogene
SPINK5 serine peptidase inhibitor, Kazal type 5
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TREM2 triggering receptor expressed on myeloid cells 2
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
TRIM27 tripartite motif containing 27
TYRO3 TYRO3 protein tyrosine kinase
USP38 ubiquitin specific peptidase 38
WDR41 WD repeat domain 41
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZDHHC18 zinc finger, DHHC-type containing 18