negative regulation of immune system process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. (Gene Ontology, GO_0002683)
External Link http://amigo.geneontology.org/amigo/term/GO:0002683
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Genes

54 genes participating in the negative regulation of immune system process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACOD1 aconitate decarboxylase 1
ADTRP androgen-dependent TFPI-regulating protein
AMBP alpha-1-microglobulin/bikunin precursor
BPIFB1 BPI fold containing family B, member 1
C9ORF72 chromosome 9 open reading frame 72
CACTIN cactin, spliceosome C complex subunit
CD200 CD200 molecule
CLEC12A C-type lectin domain family 12, member A
COL3A1 collagen, type III, alpha 1
DAB2IP DAB2 interacting protein
FADD Fas (TNFRSF6)-associated via death domain
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FOXP3 forkhead box P3
GPER1 G protein-coupled estrogen receptor 1
GPR108 G protein-coupled receptor 108
GPS2 G protein pathway suppressor 2
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HOXA7 homeobox A7
IL17D interleukin 17D
IRAK3 interleukin-1 receptor-associated kinase 3
ITCH itchy E3 ubiquitin protein ligase
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LRRC14 leucine rich repeat containing 14
LYN LYN proto-oncogene, Src family tyrosine kinase
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRP2B NLR family pyrin domain containing 2B
NR1D1 nuclear receptor subfamily 1, group D, member 1
OTUD4 OTU deubiquitinase 4
PDCD1 programmed cell death 1
RAB7B RAB7B, member RAS oncogene family
RNF115 ring finger protein 115
RNF39 ring finger protein 39
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SOX9 SRY (sex determining region Y)-box 9
SPINK5 serine peptidase inhibitor, Kazal type 5
SQSTM1 sequestosome 1
TARBP2 TAR (HIV-1) RNA binding protein 2
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TLR6 toll-like receptor 6
TMED7-TICAM2 TMED7-TICAM2 readthrough
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TREM2 triggering receptor expressed on myeloid cells 2
TRIM32 tripartite motif containing 32
TSC22D3 TSC22 domain family, member 3
TSPAN6 tetraspanin 6
TYRO3 TYRO3 protein tyrosine kinase
WDR41 WD repeat domain 41
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon