negative regulation of innate immune response Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. (Gene Ontology, GO_0045824)
External Link http://amigo.geneontology.org/amigo/term/GO:0045824
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Genes

58 genes participating in the negative regulation of innate immune response biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACOD1 aconitate decarboxylase 1
ATG12 autophagy related 12
ATG5 autophagy related 5
AURKB aurora kinase B
BANF1 barrier to autointegration factor 1
CACTIN cactin, spliceosome C complex subunit
CEP63 centrosomal protein 63kDa
CNOT7 CCR4-NOT transcription complex, subunit 7
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DCST1 DC-STAMP domain containing 1
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DTX4 deltex 4, E3 ubiquitin ligase
EIF4E2 eukaryotic translation initiation factor 4E family member 2
FAM3A family with sequence similarity 3, member A
GIGYF2 GRB10 interacting GYF protein 2
GRN granulin
IFI16 interferon, gamma-inducible protein 16
INS insulin
IRAK3 interleukin-1 receptor-associated kinase 3
ISG15 ISG15 ubiquitin-like modifier
LONP1 lon peptidase 1, mitochondrial
LYAR Ly1 antibody reactive
MAVS mitochondrial antiviral signaling protein
METTL3 methyltransferase like 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NLRC3 NLR family, CARD domain containing 3
NLRC5 NLR family, CARD domain containing 5
NLRP4 NLR family, pyrin domain containing 4
NMI N-myc (and STAT) interactor
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PARP1 poly (ADP-ribose) polymerase 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
REXO2 RNA exonuclease 2
RPS19 ribosomal protein S19
SAMHD1 SAM domain and HD domain 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLAMF8 SLAM family member 8
SMIM30 small integral membrane protein 30
STAT2 signal transducer and activator of transcription 2, 113kDa
SUSD4 sushi domain containing 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
TTLL12 tubulin tyrosine ligase-like family member 12
TYRO3 TYRO3 protein tyrosine kinase
USP15 ubiquitin specific peptidase 15
USP18 ubiquitin specific peptidase 18
USP38 ubiquitin specific peptidase 38
VSIG4 V-set and immunoglobulin domain containing 4
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZDHHC18 zinc finger, DHHC-type containing 18