negative regulation of insulin secretion Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. (Gene Ontology, GO_0046676)
External Link http://amigo.geneontology.org/amigo/term/GO:0046676
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Genes

19 genes participating in the negative regulation of insulin secretion biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
BMP8A bone morphogenetic protein 8a
CCN3 cellular communication network factor 3
CHGA chromogranin A
FAM3D family with sequence similarity 3, member D
FOXO1 forkhead box O1
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KLF7 Kruppel-like factor 7 (ubiquitous)
MIDN midnolin
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PRKN parkin RBR E3 ubiquitin protein ligase
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
REST RE1-silencing transcription factor
SFRP1 secreted frizzled-related protein 1
SIRT4 sirtuin 4