negative regulation of lyase activity Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. (Gene Ontology, GO_0051350)
External Link	http://amigo.geneontology.org/amigo/term/GO:0051350
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Genes

15 genes participating in the negative regulation of lyase activity biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
ADGRV1	adhesion G protein-coupled receptor V1
AKAP5	A kinase (PRKA) anchor protein 5
CCR2	chemokine (C-C motif) receptor 2
DRD2	dopamine receptor D2
EDNRB	endothelin receptor type B
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
GALR1	galanin receptor 1
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GRM2	glutamate receptor, metabotropic 2
GRM3	glutamate receptor, metabotropic 3
LTB4R2	leukotriene B4 receptor 2
MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase
PHPT1	phosphohistidine phosphatase 1
RD3	retinal degeneration 3