negative regulation of lymphocyte activation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. (Gene Ontology, GO_0051250)
External Link http://amigo.geneontology.org/amigo/term/GO:0051250
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Genes

28 genes participating in the negative regulation of lymphocyte activation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
BANK1 B-cell scaffold protein with ankyrin repeats 1
CLEC12A C-type lectin domain family 12, member A
CTSG cathepsin G
DUSP3 dual specificity phosphatase 3
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGL1 fibrinogen-like 1
FOXJ1 forkhead box J1
GPNMB glycoprotein (transmembrane) nmb
HLA-E major histocompatibility complex, class I, E
IL4I1 interleukin 4 induced 1
ILDR2 immunoglobulin-like domain containing receptor 2
JAK3 Janus kinase 3
LAPTM5 lysosomal protein transmembrane 5
LAX1 lymphocyte transmembrane adaptor 1
LGALS3 lectin, galactoside-binding, soluble, 3
MICA MHC class I polypeptide-related sequence A
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PDCD1 programmed cell death 1
PIBF1 progesterone immunomodulatory binding factor 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SOX11 SRY (sex determining region Y)-box 11
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIPE2 TNF alpha induced protein 8 like 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UFL1 UFM1-specific ligase 1
VTCN1 V-set domain containing T cell activation inhibitor 1