negative regulation of macroautophagy Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy. (Gene Ontology, GO_0016242)
External Link http://amigo.geneontology.org/amigo/term/GO:0016242
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Genes

27 genes participating in the negative regulation of macroautophagy biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
CLEC16A C-type lectin domain family 16, member A
FBXL4 F-box and leucine-rich repeat protein 4
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
HDAC6 histone deacetylase 6
LRRK2 leucine-rich repeat kinase 2
LYPLA1 lysophospholipase I
LZTS1 leucine zipper, putative tumor suppressor 1
MTM1 myotubularin 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NRBP2 nuclear receptor binding protein 2
NUPR1 nuclear protein, transcriptional regulator, 1
PHF23 PHD finger protein 23
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PINK1 PTEN induced putative kinase 1
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RUBCN rubicon autophagy regulator
SCFD1 sec1 family domain containing 1
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
TMEM39A transmembrane protein 39A
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36