negative regulation of programmed cell death Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. (Gene Ontology, GO_0043069)
External Link http://amigo.geneontology.org/amigo/term/GO_0043069
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Genes

382 genes participating in the negative regulation of programmed cell death biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
AHI1 Abelson helper integration site 1
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
AMH anti-Mullerian hormone
AMIGO2 adhesion molecule with Ig-like domain 2
ANGPT1 angiopoietin 1
ANGPT4 angiopoietin 4
ANGPTL4 angiopoietin-like 4
ANKLE2 ankyrin repeat and LEM domain containing 2
ANXA1 annexin A1
ANXA4 annexin A4
ANXA5 annexin A5
API5 apoptosis inhibitor 5
APIP APAF1 interacting protein
AQP1 aquaporin 1 (Colton blood group)
ARAF A-Raf proto-oncogene, serine/threonine kinase
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARF4 ADP-ribosylation factor 4
ARHGAP21 Rho GTPase activating protein 21
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ASCL1 achaete-scute family bHLH transcription factor 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATAD3A ATPase family, AAA domain containing 3A
ATF5 activating transcription factor 5
ATG5 autophagy related 5
AVEN apoptosis, caspase activation inhibitor
AVP arginine vasopressin
AXL AXL receptor tyrosine kinase
AZU1 azurocidin 1
BABAM2 BRISC and BRCA1 A complex member 2
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BARD1 BRCA1 associated RING domain 1
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BCL3 B-cell CLL/lymphoma 3
BECN1 beclin 1, autophagy related
BFAR bifunctional apoptosis regulator
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BIRC7 baculoviral IAP repeat containing 7
BIRC8 baculoviral IAP repeat containing 8
BMP4 bone morphogenetic protein 4
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
C8ORF17 chromosome 8 open reading frame 17
C8ORF4 chromosome 8 open reading frame 4
CAPN3 calpain 3, (p94)
CARD14 caspase recruitment domain family, member 14
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAT catalase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CCND2 cyclin D2
CD27 CD27 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK1 cyclin-dependent kinase 1
CDSN corneodesmosin
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFL1 cofilin 1 (non-muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CIAPIN1 cytokine induced apoptosis inhibitor 1
CIB1 calcium and integrin binding 1 (calmyrin)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC5A C-type lectin domain family 5, member A
CLN3 ceroid-lipofuscinosis, neuronal 3
COMP cartilage oligomeric matrix protein
COPS5 COP9 signalosome subunit 5
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSH cathepsin H
CX3CL1 chemokine (C-X3-C motif) ligand 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDRGK1 DDRGK domain containing 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHCR24 24-dehydrocholesterol reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DPEP1 dipeptidase 1 (renal)
DPP8 dipeptidyl-peptidase 8
DPP9 dipeptidyl-peptidase 9
DSTYK dual serine/threonine and tyrosine protein kinase
EGFR epidermal growth factor receptor
EGR3 early growth response 3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC5 excision repair cross-complementation group 5
EVI2B ecotropic viral integration site 2B
FABP1 fatty acid binding protein 1, liver
FAIM2 Fas apoptotic inhibitory molecule 2
FAM46B family with sequence similarity 46, member B
FANK1 fibronectin type III and ankyrin repeat domains 1
FAS Fas cell surface death receptor
FATE1 fetal and adult testis expressed 1
FCMR Fc fragment of IgM receptor
FFAR4 free fatty acid receptor 4
FHL2 four and a half LIM domains 2
FIGNL1 fidgetin-like 1
FKBP8 FK506 binding protein 8, 38kDa
FLNA filamin A, alpha
FLT4 fms-related tyrosine kinase 4
FMN2 formin 2
FOXE3 forkhead box E3
FOXO1 forkhead box O1
FSTL1 follistatin-like 1
FXN frataxin
GAS6 growth arrest-specific 6
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA6 GATA binding protein 6
GCG glucagon
GCLC glutamate-cysteine ligase, catalytic subunit
GDNF glial cell derived neurotrophic factor
GHRL ghrelin/obestatin prepropeptide
GLO1 glyoxalase I
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPX4 glutathione peroxidase 4
GREM1 gremlin 1, DAN family BMP antagonist
GRK5 G protein-coupled receptor kinase 5
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HAX1 HCLS1 associated protein X-1
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIPK3 homeodomain interacting protein kinase 3
HMGA2 high mobility group AT-hook 2
HMGN5 high mobility group nucleosome binding domain 5
HNRNPK heterogeneous nuclear ribonucleoprotein K
HPN hepsin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HYPK huntingtin interacting protein K
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL31RA interleukin 31 receptor A
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
ITCH itchy E3 ubiquitin protein ligase
KANK2 KN motif and ankyrin repeat domains 2
KDR kinase insert domain receptor
KHDC3L KH domain containing 3-like, subcortical maternal complex member
KIF14 kinesin family member 14
KLHL20 kelch-like family member 20
KRT18 keratin 18, type I
LACRT lacritin
LAPTM5 lysosomal protein transmembrane 5
LEF1 lymphoid enhancer-binding factor 1
LRP2 low density lipoprotein receptor-related protein 2
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTF lactotransferrin
LTK leukocyte receptor tyrosine kinase
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGEA4 melanoma antigen family A4
MALT1 MALT1 paracaspase
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MED1 mediator complex subunit 1
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIEN1 migration and invasion enhancer 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MRE11 MRE11 homolog, double strand break repair nuclease
MT3 metallothionein 3
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYDGF myeloid-derived growth factor
MYO18A myosin XVIIIA
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAIP NLR family, apoptosis inhibitory protein
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
NCKAP1L NCK-associated protein 1-like
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIBAN2 niban apoptosis regulator 2
NKX2-5 NK2 homeobox 5
NKX2-6 NK2 homeobox 6
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOTCH2 notch 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTSR1 neurotensin receptor 1 (high affinity)
NUAK2 NUAK family, SNF1-like kinase, 2
NUGGC nuclear GTPase, germinal center associated
NUP62 nucleoporin 62kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OPA1 optic atrophy 1 (autosomal dominant)
OPN3 opsin 3
OXSR1 oxidative stress responsive 1
PA2G4 proliferation-associated 2G4, 38kDa
PAGE4 P antigen family, member 4 (prostate associated)
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAX2 paired box 2
PAX7 paired box 7
PCID2 PCI domain containing 2
PDCD10 programmed cell death 10
PDPN podoplanin
PEPD peptidase D
PHB2 prohibitin 2
PHIP pleckstrin homology domain interacting protein
PIDD1 p53-induced death domain protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLAUR plasminogen activator, urokinase receptor
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
POU3F3 POU class 3 homeobox 3
POU4F1 POU class 4 homeobox 1
PPIF peptidylprolyl isomerase F
PPT1 palmitoyl-protein thioesterase 1
PRAME preferentially expressed antigen in melanoma
PRAP1 proline-rich acidic protein 1
PRDM9 PR domain containing 9
PRDX2 peroxiredoxin 2
PRDX3 peroxiredoxin 3
PRDX5 peroxiredoxin 5
PRELID1 PRELI domain containing 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCI protein kinase C, iota
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRLR prolactin receptor
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROK2 prokineticin 2
PRR5 proline rich 5 (renal)
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTMA prothymosin, alpha
PTMS parathymosin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHBDD1 rhomboid domain containing 1
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF144B ring finger protein 144B
RNF157 ring finger protein 157
RPL10 ribosomal protein L10
RPS3A ribosomal protein S3A
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCX scleraxis basic helix-loop-helix transcription factor
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SETX senataxin
SFRP1 secreted frizzled-related protein 1
SH3RF1 SH3 domain containing ring finger 1
SH3RF2 SH3 domain containing ring finger 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SIAH2 siah E3 ubiquitin protein ligase 2
SIRT1 sirtuin 1
SIX4 SIX homeobox 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SON SON DNA binding protein
SOX8 SRY (sex determining region Y)-box 8
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STIL SCL/TAL1 interrupting locus
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBX3 T-box 3
TCL1A T-cell leukemia/lymphoma 1A
TDGF1 teratocarcinoma-derived growth factor 1
TEK TEK tyrosine kinase, endothelial
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFRC transferrin receptor
THBS1 thrombospondin 1
THOC6 THO complex 6
TIGAR TP53 induced glycolysis regulatory phosphatase
TJP1 tight junction protein 1
TM7SF3 transmembrane 7 superfamily member 3
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM109 transmembrane protein 109
TMEM14A transmembrane protein 14A
TMIGD1 transmembrane and immunoglobulin domain containing 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TP53 tumor protein p53
TPT1 tumor protein, translationally-controlled 1
TREM2 triggering receptor expressed on myeloid cells 2
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TSC22D1 TSC22 domain family, member 1
TSLP thymic stromal lymphopoietin
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBE2Z ubiquitin-conjugating enzyme E2Z
UFM1 ubiquitin-fold modifier 1
USP47 ubiquitin specific peptidase 47
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIP vasoactive intestinal peptide
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR73 WD repeat domain 73
WFS1 Wolfram syndrome 1 (wolframin)
WNK3 WNK lysine deficient protein kinase 3
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YME1L1 YME1-like 1 ATPase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFAND6 zinc finger, AN1-type domain 6
ZNF16 zinc finger protein 16
ZNF268 zinc finger protein 268
ZNF830 zinc finger protein 830