negative regulation of protein secretion Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. (Gene Ontology, GO_0050709)
External Link http://amigo.geneontology.org/amigo/term/GO:0050709
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Genes

41 genes participating in the negative regulation of protein secretion biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
ADTRP androgen-dependent TFPI-regulating protein
APOE apolipoprotein E
BMP8A bone morphogenetic protein 8a
CCN3 cellular communication network factor 3
CD200 CD200 molecule
CHGA chromogranin A
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DPH3 diphthamide biosynthesis 3
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
ERP29 endoplasmic reticulum protein 29
F2R coagulation factor II (thrombin) receptor
FAM3D family with sequence similarity 3, member D
FOXO1 forkhead box O1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IL12A interleukin 12A
IL12B interleukin 12B
IL1B interleukin 1, beta
INHBB inhibin, beta B
INS insulin
IRS1 insulin receptor substrate 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
MIDN midnolin
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPRM1 opioid receptor, mu 1
PRKN parkin RBR E3 ubiquitin protein ligase
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
REST RE1-silencing transcription factor
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RSAD2 radical S-adenosyl methionine domain containing 2
SERGEF secretion regulating guanine nucleotide exchange factor
SFRP1 secreted frizzled-related protein 1
SIRT4 sirtuin 4