negative regulation of proteolysis Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. (Gene Ontology, GO_0045861)
External Link http://amigo.geneontology.org/amigo/term/GO:0045861
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Genes

41 genes participating in the negative regulation of proteolysis biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACP4 acid phosphatase 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAG6 BCL2-associated athanogene 6
CDK5 cyclin-dependent kinase 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CST3 cystatin C
CST4 cystatin S
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
ECM1 extracellular matrix protein 1
EFNA1 ephrin-A1
EPHA4 EPH receptor A4
EPPIN epididymal peptidase inhibitor
GAS1 growth arrest-specific 1
HDAC6 histone deacetylase 6
IL10 interleukin 10
KNG1 kininogen 1
LRRK2 leucine-rich repeat kinase 2
MAGEA3 melanoma antigen family A3
NLRP7 NLR family, pyrin domain containing 7
PLAT plasminogen activator, tissue
PRNP prion protein
PTPN3 protein tyrosine phosphatase, non-receptor type 3
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SNX12 sorting nexin 12
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TM4SF20 transmembrane 4 L six family member 20
TTF2 transcription termination factor, RNA polymerase II
UBXN2A UBX domain protein 2A
UFSP2 UFM1-specific peptidase 2
USP17L2 ubiquitin specific peptidase 17-like family member 2