negative regulation of smoothened signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling. (Gene Ontology, GO_0045879)
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28 genes participating in the negative regulation of smoothened signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CD3E CD3e molecule, epsilon (CD3-TCR complex)
FGFR3 fibroblast growth factor receptor 3
GAS1 growth arrest-specific 1
GLI3 GLI family zinc finger 3
GLIS2 GLIS family zinc finger 2
GPC3 glypican 3
GPR161 G protein-coupled receptor 161
GPR37L1 G protein-coupled receptor 37 like 1
HHIP hedgehog interacting protein
IFT122 intraflagellar transport 122
KCTD11 potassium channel tetramerization domain containing 11
KIF7 kinesin family member 7
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTCH1 patched 1
PTCH2 patched 2
RB1 retinoblastoma 1
RFX4 regulatory factor X, 4 (influences HLA class II expression)
RUNX2 runt-related transcription factor 2
SALL1 spalt-like transcription factor 1
SALL3 spalt-like transcription factor 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SUFU suppressor of fused homolog (Drosophila)
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TULP3 tubby like protein 3
ULK3 unc-51 like kinase 3
WNT7B wingless-type MMTV integration site family, member 7B