negative regulation of synaptic transmission Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. (Gene Ontology, GO_0050805)
External Link http://amigo.geneontology.org/amigo/term/GO:0050805
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Genes

17 genes participating in the negative regulation of synaptic transmission biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ADIPOQ adiponectin, C1Q and collagen domain containing
ARF1 ADP-ribosylation factor 1
ATAD1 ATPase family, AAA domain containing 1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
GRIK3 glutamate receptor, ionotropic, kainate 3
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
IL1B interleukin 1, beta
PICK1 protein interacting with PRKCA 1
PLK2 polo-like kinase 2
PMCH pro-melanin-concentrating hormone
PRRT1 proline-rich transmembrane protein 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
STXBP1 syntaxin binding protein 1