negative regulation of transforming growth factor beta receptor signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway. (Gene Ontology, GO_0030512)
External Link http://amigo.geneontology.org/amigo/term/GO:0030512
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Genes

86 genes participating in the negative regulation of transforming growth factor beta receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADAMTSL2 ADAMTS-like 2
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID4B AT rich interactive domain 4B (RBP1-like)
ASPN asporin
BAMBI BMP and activin membrane-bound inhibitor
BCL9L B-cell CLL/lymphoma 9-like
BMP2 bone morphogenetic protein 2
BRMS1L breast cancer metastasis-suppressor 1-like
CD109 CD109 molecule
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CIDEA cell death-inducing DFFA-like effector a
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
DAND5 DAN domain family member 5, BMP antagonist
EID2 EP300 interacting inhibitor of differentiation 2
EMILIN1 elastin microfibril interfacer 1
ENG endoglin
FAM89B family with sequence similarity 89, member B
FBN1 fibrillin 1
FBN2 fibrillin 2
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1C FK506 binding protein 1C
GDF15 growth differentiation factor 15
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HSPA1A heat shock 70kDa protein 1A
HTRA3 HtrA serine peptidase 3
HTRA4 HtrA serine peptidase 4
IL17RD interleukin 17 receptor D
ING1 inhibitor of growth family, member 1
ING3 inhibitor of growth family, member 3
INTS9 integrator complex subunit 9
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEMD3 LEM domain containing 3
LRRC32 leucine rich repeat containing 32
LTBP1 latent transforming growth factor beta binding protein 1
MECOM MDS1 and EVI1 complex locus
MTMR4 myotubularin related protein 4
NKX2-1 NK2 homeobox 1
NRROS negative regulator of reactive oxygen species
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OVOL2 ovo-like zinc finger 2
PBLD phenazine biosynthesis-like protein domain containing
PDPK1 3-phosphoinositide dependent protein kinase 1
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
PMEPA1 prostate transmembrane protein, androgen induced 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PRDM16 PR domain containing 16
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
SAP130 Sin3A-associated protein, 130kDa
SAP30 Sin3A-associated protein, 30kDa
SAP30L SAP30-like
SIN3A SIN3 transcription regulator family member A
SINHCAF SIN3-HDAC complex associated factor
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SKOR2 SKI family transcriptional corepressor 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNX25 sorting nexin 25
SNX6 sorting nexin 6
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SRFBP1 serum response factor binding protein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
TET1 tet methylcytosine dioxygenase 1
USP15 ubiquitin specific peptidase 15
VASN vasorin
VEPH1 ventricular zone expressed PH domain-containing 1
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
XBP1 X-box binding protein 1
ZBTB7A zinc finger and BTB domain containing 7A
ZNF451 zinc finger protein 451