| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the neomycin-2066 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ANGPTL2 | angiopoietin-like 2 |
| AOX1 | aldehyde oxidase 1 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| AQR | aquarius intron-binding spliceosomal factor |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BCL2L1 | BCL2-like 1 |
| BRD4 | bromodomain containing 4 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CD80 | CD80 molecule |
| CEP250 | centrosomal protein 250kDa |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CUL5 | cullin 5 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| FOXA2 | forkhead box A2 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GLG1 | golgi glycoprotein 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| H2AFX | H2A histone family, member X |
| HHIPL2 | HHIP-like 2 |
| HIST1H3G | histone cluster 1, H3g |
| HLA-G | major histocompatibility complex, class I, G |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFNA14 | interferon, alpha 14 |
| IL17RC | interleukin 17 receptor C |
| IRGC | immunity-related GTPase family, cinema |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT85 | keratin 85, type II |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMC3 | laminin, gamma 3 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LRRN2 | leucine rich repeat neuronal 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MEF2A | myocyte enhancer factor 2A |
| MEGF9 | multiple EGF-like-domains 9 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO9B | myosin IXB |
| NADK | NAD kinase |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PLA2G10 | phospholipase A2, group X |
| PLSCR4 | phospholipid scramblase 4 |
| PODXL2 | podocalyxin-like 2 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLN | sarcolipin |
| SPTB | spectrin, beta, erythrocytic |
| SQSTM1 | sequestosome 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| THBS3 | thrombospondin 3 |
| TLN2 | talin 2 |
| TMEM242 | transmembrane protein 242 |
| TSPAN12 | tetraspanin 12 |
| TSPAN2 | tetraspanin 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| USP20 | ubiquitin specific peptidase 20 |
| WAS | Wiskott-Aldrich syndrome |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WDR18 | WD repeat domain 18 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF230 | zinc finger protein 230 |
| ZNF34 | zinc finger protein 34 |
| ZNF480 | zinc finger protein 480 |
| ZNF580 | zinc finger protein 580 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| Symbol | Name |
|---|---|
| ACYP2 | acylphosphatase 2, muscle type |
| ADAMTSL3 | ADAMTS-like 3 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP10D | ATPase, class V, type 10D |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CBR4 | carbonyl reductase 4 |
| CCDC85C | coiled-coil domain containing 85C |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CLDN15 | claudin 15 |
| COBL | cordon-bleu WH2 repeat protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTSV | cathepsin V |
| CUL9 | cullin 9 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEAF1 | DEAF1 transcription factor |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| EPN3 | epsin 3 |
| ERF | Ets2 repressor factor |
| FBXO2 | F-box protein 2 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GBX2 | gastrulation brain homeobox 2 |
| GTPBP2 | GTP binding protein 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HMOX1 | heme oxygenase 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL4R | interleukin 4 receptor |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIF13B | kinesin family member 13B |
| KIF20A | kinesin family member 20A |
| KIFC1 | kinesin family member C1 |
| KRT86 | keratin 86, type II |
| LMNB1 | lamin B1 |
| LOC100127972 | uncharacterized LOC100127972 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MBD5 | methyl-CpG binding domain protein 5 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOXD1 | monooxygenase, DBH-like 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NRSN2 | neurensin 2 |
| OLFML2A | olfactomedin-like 2A |
| OTUD3 | OTU deubiquitinase 3 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PISD | phosphatidylserine decarboxylase |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| RAB23 | RAB23, member RAS oncogene family |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| S100A4 | S100 calcium binding protein A4 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SETD6 | SET domain containing 6 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SPEG | SPEG complex locus |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TKFC | triokinase/FMN cyclase |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRABD | TraB domain containing |
| TRIM21 | tripartite motif containing 21 |
| TRIM62 | tripartite motif containing 62 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| WDR76 | WD repeat domain 76 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF136 | zinc finger protein 136 |
| ZNF232 | zinc finger protein 232 |
| ZNF33B | zinc finger protein 33B |
| ZNF551 | zinc finger protein 551 |
| ZNF611 | zinc finger protein 611 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF862 | zinc finger protein 862 |