neomycin-2229 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the neomycin-2229 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACTC1 actin, alpha, cardiac muscle 1
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AQP5 aquaporin 5
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP9B ATPase, class II, type 9B
BCAN brevican
BMP1 bone morphogenetic protein 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CD209 CD209 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDHR2 cadherin-related family member 2
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CLCN7 chloride channel, voltage-sensitive 7
CLIC2 chloride intracellular channel 2
COL6A1 collagen, type VI, alpha 1
CPNE7 copine VII
CRISP2 cysteine-rich secretory protein 2
CT55 cancer/testis antigen 55
CYB5A cytochrome b5 type A (microsomal)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCX doublecortin
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DLX2 distal-less homeobox 2
DOK4 docking protein 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGFR epidermal growth factor receptor
EPHB1 EPH receptor B1
EXOC6B exocyst complex component 6B
FAM76A family with sequence similarity 76, member A
FGF13 fibroblast growth factor 13
FRMD1 FERM domain containing 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPM6A glycoprotein M6A
GRAMD1C GRAM domain containing 1C
GRM6 glutamate receptor, metabotropic 6
HBB hemoglobin, beta
HLF hepatic leukemia factor
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ICAM2 intercellular adhesion molecule 2
ICOSLG inducible T-cell co-stimulator ligand
IL1R1 interleukin 1 receptor, type I
INO80D INO80 complex subunit D
ITM2A integral membrane protein 2A
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF13 Kruppel-like factor 13
KLHDC8A kelch domain containing 8A
KLHL20 kelch-like family member 20
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMA2 laminin, alpha 2
LINC00652 long intergenic non-protein coding RNA 652
LOC100127972 uncharacterized LOC100127972
LOX lysyl oxidase
MTSS1L metastasis suppressor 1-like
NEB nebulin
NF2 neurofibromin 2 (merlin)
OXT oxytocin/neurophysin I prepropeptide
PAPPA2 pappalysin 2
PAX2 paired box 2
PCBP3 poly(rC) binding protein 3
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PLIN2 perilipin 2
PLXNB3 plexin B3
POU6F2 POU class 6 homeobox 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRUNE2 prune homolog 2 (Drosophila)
PTAFR platelet-activating factor receptor
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PURA purine-rich element binding protein A
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SECTM1 secreted and transmembrane 1
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SMAD1 SMAD family member 1
SMG6 SMG6 nonsense mediated mRNA decay factor
SP100 SP100 nuclear antigen
SRPX2 sushi-repeat containing protein, X-linked 2
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
STOML1 stomatin (EPB72)-like 1
STXBP5L syntaxin binding protein 5-like
TMEM206 transmembrane protein 206
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOX thymocyte selection-associated high mobility group box
TPP1 tripeptidyl peptidase I
WDR55 WD repeat domain 55
XYLT1 xylosyltransferase I
ZNF280A zinc finger protein 280A
ZNF76 zinc finger protein 76
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
AHNAK2 AHNAK nucleoprotein 2
ARC activity-regulated cytoskeleton-associated protein
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATAT1 alpha tubulin acetyltransferase 1
C11ORF30 chromosome 11 open reading frame 30
C11ORF80 chromosome 11 open reading frame 80
C17ORF53 chromosome 17 open reading frame 53
C4ORF29 chromosome 4 open reading frame 29
C9ORF9 chromosome 9 open reading frame 9
CA5BP1 carbonic anhydrase VB pseudogene 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD79B CD79b molecule, immunoglobulin-associated beta
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHST10 carbohydrate sulfotransferase 10
CLCN2 chloride channel, voltage-sensitive 2
CLCN5 chloride channel, voltage-sensitive 5
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSF1R colony stimulating factor 1 receptor
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP13 dual specificity phosphatase 13
DUSP2 dual specificity phosphatase 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM110B family with sequence similarity 110, member B
FAM155A family with sequence similarity 155, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FOSL1 FOS-like antigen 1
FRK fyn-related Src family tyrosine kinase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM5 glutathione S-transferase mu 5
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
IRF6 interferon regulatory factor 6
JMJD4 jumonji domain containing 4
KIAA0319L KIAA0319-like
KRT15 keratin 15, type I
LAMB3 laminin, beta 3
LARP6 La ribonucleoprotein domain family, member 6
LHX6 LIM homeobox 6
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MON1B MON1 secretory trafficking family member B
NOL12 nucleolar protein 12
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PALM paralemmin
PCDHA6 protocadherin alpha 6
PICK1 protein interacting with PRKCA 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
POLH polymerase (DNA directed), eta
PQLC2 PQ loop repeat containing 2
PRODH proline dehydrogenase (oxidase) 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A4 S100 calcium binding protein A4
SEC14L5 SEC14-like 5 (S. cerevisiae)
SETD1A SET domain containing 1A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHARPIN SHANK-associated RH domain interactor
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLIT2 slit homolog 2 (Drosophila)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX3 SRY (sex determining region Y)-box 3
SPON2 spondin 2, extracellular matrix protein
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
SYNC syncoilin, intermediate filament protein
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TRIM66 tripartite motif containing 66
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TWF2 twinfilin actin binding protein 2
VASH1 vasohibin 1
VIM vimentin
VLDLR very low density lipoprotein receptor
WDR33 WD repeat domain 33
WDR62 WD repeat domain 62
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YEATS2 YEATS domain containing 2
ZBTB39 zinc finger and BTB domain containing 39
ZNF136 zinc finger protein 136
ZNF446 zinc finger protein 446
ZNF480 zinc finger protein 480
ZNF532 zinc finger protein 532
ZNF611 zinc finger protein 611
ZNF675 zinc finger protein 675