neoplasms Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
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Genes

126 genes associated with the disease neoplasms in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ACP1 acid phosphatase 1, soluble
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CAPN6 calpain 6
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CCR1 chemokine (C-C motif) receptor 1
CD3EAP CD3e molecule, epsilon associated protein
CD80 CD80 molecule
CD86 CD86 molecule
CDA cytidine deaminase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCK deoxycytidine kinase
DPYD dihydropyrimidine dehydrogenase
EGF epidermal growth factor
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FADS1 fatty acid desaturase 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FSTL5 follistatin-like 5
GPX1 glutathione peroxidase 1
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HNF1B HNF1 homeobox B
HP haptoglobin
IKZF2 IKAROS family zinc finger 2 (Helios)
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL16 interleukin 16
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAK1 Janus kinase 1
LTA lymphotoxin alpha
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEGF11 multiple EGF-like-domains 11
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGMT O-6-methylguanine-DNA methyltransferase
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBN nibrin
NCOR2 nuclear receptor corepressor 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PARP1 poly (ADP-ribose) polymerase 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POLI polymerase (DNA directed) iota
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRDM16 PR domain containing 16
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RMI1 RecQ mediated genome instability 1
SH3GL2 SH3-domain GRB2-like 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SOCS2 suppressor of cytokine signaling 2
SOCS5 suppressor of cytokine signaling 5
SOD2 superoxide dismutase 2, mitochondrial
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TOP3A topoisomerase (DNA) III alpha
TP53 tumor protein p53
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4