nephroblastoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A kidney cancer that affects the kidneys and typically located_in children. (Human Disease Ontology, DOID_2154)
Similar Terms
Downloads & Tools

Genes

369 genes co-occuring with the disease nephroblastoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
WT1 Wilms tumor 1 3.81156
LATS1 large tumor suppressor kinase 1 2.13971
IGF2 insulin-like growth factor 2 1.90614
NOV nephroblastoma overexpressed 1.82413
KLF10 Kruppel-like factor 10 1.78263
MECOM MDS1 and EVI1 complex locus 1.72183
WTAP Wilms tumor 1 associated protein 1.6359
CYR61 cysteine-rich, angiogenic inducer, 61 1.58894
CTGF connective tissue growth factor 1.54407
PAX2 paired box 2 1.50755
EGR1 early growth response 1 1.38647
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 1.38036
WISP2 WNT1 inducible signaling pathway protein 2 1.37599
DIS3L2 DIS3 like 3'-5' exoribonuclease 2 1.35899
PAX6 paired box 6 1.32934
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.30663
WT1-AS WT1 antisense RNA 1.28566
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.28566
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.27214
TP53 tumor protein p53 1.25515
EWSR1 EWS RNA-binding protein 1 1.23343
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.20872
POU6F2 POU class 6 homeobox 2 1.20699
YIPF2 Yip1 domain family, member 2 1.17464
WISP3 WNT1 inducible signaling pathway protein 3 1.16606
PRDM2 PR domain containing 2, with ZNF domain 1.16521
WISP1 WNT1 inducible signaling pathway protein 1 1.16093
SYNPO synaptopodin 1.1051
FSHB follicle stimulating hormone, beta polypeptide 1.07236
BASP1 brain abundant, membrane attached signal protein 1 1.06228
MPPED2 metallophosphoesterase domain containing 2 1.05261
SIX2 SIX homeobox 2 1.03535
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.02945
PDGFA platelet-derived growth factor alpha polypeptide 1.00203
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.998236
NAP1L4 nucleosome assembly protein 1-like 4 0.984743
GPC3 glypican 3 0.965405
MDK midkine (neurite growth-promoting factor 2) 0.964148
ENO2 enolase 2 (gamma, neuronal) 0.951187
ZSCAN26 zinc finger and SCAN domain containing 26 0.937044
EGR4 early growth response 4 0.925452
PAX8 paired box 8 0.922149
IGF1R insulin-like growth factor 1 receptor 0.920085
SRY sex determining region Y 0.919673
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.911433
CIAO1 cytosolic iron-sulfur assembly component 1 0.889668
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.887208
NCAM1 neural cell adhesion molecule 1 0.877376
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.871643
PTPRO protein tyrosine phosphatase, receptor type, O 0.870415
CALB2 calbindin 2 0.859362
B3GAT1 beta-1,3-glucuronyltransferase 1 0.852402
LBX1 ladybird homeobox 1 0.852402
ZNF219 zinc finger protein 219 0.842163
HLA-A major histocompatibility complex, class I, A 0.840934
CD34 CD34 molecule 0.837656
NUMBL numb homolog (Drosophila)-like 0.817565
LHX1 LIM homeobox 1 0.815514
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.806488
ZNF181 zinc finger protein 181 0.792951
ZNF302 zinc finger protein 302 0.792951
DCLRE1B DNA cross-link repair 1B 0.792951
ZNF599 zinc finger protein 599 0.792951
ZNF30 zinc finger protein 30 0.792951
METTL14 methyltransferase like 14 0.787213
WTIP Wilms tumor 1 interacting protein 0.783936
YIPF1 Yip1 domain family, member 1 0.779841
NNAT neuronatin 0.776977
HTN3 histatin 3 0.776977
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 0.765535
SLC22A18 solute carrier family 22, member 18 0.757786
YIPF4 Yip1 domain family, member 4 0.752085
IGF2-AS IGF2 antisense RNA 0.746391
METTL3 methyltransferase like 3 0.744766
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.739488
EGR2 early growth response 2 0.733001
ZNF174 zinc finger protein 174 0.728143
CAT catalase 0.722886
PODXL podocalyxin-like 0.722077
SOX9 SRY (sex determining region Y)-box 9 0.712392
REN renin 0.710378
CTCF CCCTC-binding factor (zinc finger protein) 0.70434
KRT7 keratin 7, type II 0.692697
FOXD2 forkhead box D2 0.687491
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.681495
PCDHG@ protocadherin gamma cluster 0.669538
BAALC brain and acute leukemia, cytoplasmic 0.6608
STIM1 stromal interaction molecule 1 0.660404
TFE3 transcription factor binding to IGHM enhancer 3 0.657234
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.65565
IVNS1ABP influenza virus NS1A binding protein 0.650903
TSSC1 tumor suppressing subtransferable candidate 1 0.648138
WNT1 wingless-type MMTV integration site family, member 1 0.64577
TRIM22 tripartite motif containing 22 0.634742
LUZP2 leucine zipper protein 2 0.63042
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.622183
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.61866
FAXDC2 fatty acid hydroxylase domain containing 2 0.618268
CD99 CD99 molecule 0.603811
PTER phosphotriesterase related 0.60186
MYOD1 myogenic differentiation 1 0.60069
AREG amphiregulin 0.6003
MYH11 myosin, heavy chain 11, smooth muscle 0.594064
AMER1 APC membrane recruitment protein 1 0.585108
ESR1 estrogen receptor 1 0.581996
SALL2 spalt-like transcription factor 2 0.581217
HRAS Harvey rat sarcoma viral oncogene homolog 0.579661
KRT5 keratin 5, type II 0.574217
CLUH clustered mitochondria (cluA/CLU1) homolog 0.571884
KCNK15 potassium channel, two pore domain subfamily K, member 15 0.569552
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.559062
RNF167 ring finger protein 167 0.557509
SOX12 SRY (sex determining region Y)-box 12 0.554015
ZHX1 zinc fingers and homeoboxes 1 0.554015
CBY1 chibby homolog 1 (Drosophila) 0.551298
AMH anti-Mullerian hormone 0.549747
CORO1B coronin, actin binding protein, 1B 0.548971
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.547419
ZNF224 zinc finger protein 224 0.544318
PRM3 protamine 3 0.534248
PHTF1 putative homeodomain transcription factor 1 0.531928
FLT3 fms-related tyrosine kinase 3 0.529994
ZNF346 zinc finger protein 346 0.527676
MAF1 MAF1 homolog (S. cerevisiae) 0.52729
AFP alpha-fetoprotein 0.526904
SIX1 SIX homeobox 1 0.526132
RPL10 ribosomal protein L10 0.522659
SALL1 spalt-like transcription factor 1 0.512264
MYOG myogenin (myogenic factor 4) 0.511496
THRAP3 thyroid hormone receptor associated protein 3 0.505356
LRRC15 leucine rich repeat containing 15 0.503058
CD2AP CD2-associated protein 0.499231
EGR3 early growth response 3 0.494266
PARD6B par-6 family cell polarity regulator beta 0.488549
KIRREL kin of IRRE like (Drosophila) 0.484364
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.475634
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.474119
EGFR epidermal growth factor receptor 0.470332
BAIAP3 BAI1-associated protein 3 0.468063
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.466928
PRTN3 proteinase 3 0.466928
TCF21 transcription factor 21 0.461261
IGF1 insulin-like growth factor 1 (somatomedin C) 0.461261
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.458996
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.457487
LHX9 LIM homeobox 9 0.457109
ASCL2 achaete-scute family bHLH transcription factor 2 0.449947
ERBB2 erb-b2 receptor tyrosine kinase 2 0.447311
TERT telomerase reverse transcriptase 0.446182
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.445805
NKX2-1 NK2 homeobox 1 0.445052
NUTM2B NUT family member 2B 0.442795
TGFB1 transforming growth factor, beta 1 0.43941
HLA-C major histocompatibility complex, class I, C 0.438658
SYP synaptophysin 0.437154
BAX BCL2-associated X protein 0.435651
ZNF569 zinc finger protein 569 0.433772
ZNF629 zinc finger protein 629 0.433772
ZNF763 zinc finger protein 763 0.433772
ZNF501 zinc finger protein 501 0.433772
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.433021
PAX3 paired box 3 0.43227
POU4F2 POU class 4 homeobox 2 0.431144
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.42814
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.421765
ZNF44 zinc finger protein 44 0.421016
PTN pleiotrophin 0.420266
GATA4 GATA binding protein 4 0.417644
DICER1 dicer 1, ribonuclease type III 0.417644
RARA retinoic acid receptor, alpha 0.41465
ZNF410 zinc finger protein 410 0.411657
INHA inhibin, alpha 0.409787
PRCC papillary renal cell carcinoma (translocation-associated) 0.408292
SCEL sciellin 0.407545
BCL6B B-cell CLL/lymphoma 6, member B 0.405305
ZFPM2 zinc finger protein, FOG family member 2 0.404184
PRAME preferentially expressed antigen in melanoma 0.403064
MB myoglobin 0.399334
PCDH11Y protocadherin 11 Y-linked 0.396353
IRX5 iroquois homeobox 5 0.392629
MTPAP mitochondrial poly(A) polymerase 0.387423
RENBP renin binding protein 0.384822
TCERG1L transcription elongation regulator 1-like 0.383708
AR androgen receptor 0.383708
THBS1 thrombospondin 1 0.379256
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.378143
PAX7 paired box 7 0.377031
BCL2L1 BCL2-like 1 0.37629
GAS2 growth arrest-specific 2 0.369258
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.368149
KRT20 keratin 20, type I 0.367779
PAWR PRKC, apoptosis, WT1, regulator 0.36704
TBX18 T-box 18 0.363716
AURKAIP1 aurora kinase A interacting protein 1 0.362609
CADM4 cell adhesion molecule 4 0.362609
FZD7 frizzled class receptor 7 0.359289
MEOX1 mesenchyme homeobox 1 0.35892
FSHR follicle stimulating hormone receptor 0.354868
MVP major vault protein 0.354499
GDNF glial cell derived neurotrophic factor 0.353395
CD59 CD59 molecule, complement regulatory protein 0.353027
PCDH11X protocadherin 11 X-linked 0.352659
DLK1 delta-like 1 homolog (Drosophila) 0.351187
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.35082
ST20 suppressor of tumorigenicity 20 0.347511
UBN1 ubinuclein 1 0.345675
ACTN4 actinin, alpha 4 0.343473
ZNF274 zinc finger protein 274 0.338707
F8A2 coagulation factor VIII-associated 2 0.338341
F8A1 coagulation factor VIII-associated 1 0.338341
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.337608
LGALS4 lectin, galactoside-binding, soluble, 4 0.335412
PCDHGA10 protocadherin gamma subfamily A, 10 0.332852
SULF1 sulfatase 1 0.325916
ZNF436 zinc finger protein 436 0.325552
BCLAF1 BCL2-associated transcription factor 1 0.325552
VEGFA vascular endothelial growth factor A 0.322637
S1PR2 sphingosine-1-phosphate receptor 2 0.321181
CXXC4 CXXC finger protein 4 0.321181
UBE2H ubiquitin-conjugating enzyme E2H 0.320454
DGKB diacylglycerol kinase, beta 90kDa 0.31464
ZC3H13 zinc finger CCCH-type containing 13 0.311377
WWOX WW domain containing oxidoreductase 0.309204
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.30848
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.308118
WNT11 wingless-type MMTV integration site family, member 11 0.307395
HDAC1 histone deacetylase 1 0.304142
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.300533
PCNA proliferating cell nuclear antigen 0.299452
MSLN mesothelin 0.298371
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.297291
KREMEN1 kringle containing transmembrane protein 1 0.296211
WFDC1 WAP four-disulfide core domain 1 0.295492
ITGA8 integrin, alpha 8 0.294053
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.291898
GPC4 glypican 4 0.290462
EYA1 EYA transcriptional coactivator and phosphatase 1 0.290103
BMPER BMP binding endothelial regulator 0.289744
BLCAP bladder cancer associated protein 0.28831
SLK STE20-like kinase 0.286877
DEPDC1 DEP domain containing 1 0.286877
RPL34 ribosomal protein L34 0.283297
PBX1 pre-B-cell leukemia homeobox 1 0.28151
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.28151
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.280082
NF1 neurofibromin 1 0.279367
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.279011
CD44 CD44 molecule (Indian blood group) 0.278297
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.27794
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.277584
CLDN1 claudin 1 0.27687
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.276158
RB1 retinoblastoma 1 0.266558
GPR39 G protein-coupled receptor 39 0.266558
CLDN7 claudin 7 0.263722
E2F3 E2F transcription factor 3 0.262306
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.261952
RIN1 Ras and Rab interactor 1 0.261952
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.261952
CCNA2 cyclin A2 0.261245
SOSTDC1 sclerostin domain containing 1 0.259477
ALB albumin 0.257005
AGO2 argonaute RISC catalytic component 2 0.254536
CCND1 cyclin D1 0.253831
RNF4 ring finger protein 4 0.251015
APOC1 apolipoprotein C-I 0.250311
ELP4 elongator acetyltransferase complex subunit 4 0.249257
MLANA melan-A 0.247852
NUF2 NUF2, NDC80 kinetochore complex component 0.246448
POR P450 (cytochrome) oxidoreductase 0.245396
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.245046
SSX2B synovial sarcoma, X breakpoint 2B 0.244345
TFEB transcription factor EB 0.241546
FBXO5 F-box protein 5 0.241196
IRX6 iroquois homeobox 6 0.239799
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.238752
PGR progesterone receptor 0.237357
IRX1 iroquois homeobox 1 0.237357
TRIM33 tripartite motif containing 33 0.236312
BDNF brain-derived neurotrophic factor 0.235268
KIF20A kinesin family member 20A 0.23353
TLE4 transducin-like enhancer of split 4 0.233183
ZNF222 zinc finger protein 222 0.233183
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.231795
HBB hemoglobin, beta 0.231448
CD4 CD4 molecule 0.230063
FZD2 frizzled class receptor 2 0.226607
CST3 cystatin C 0.222822
FAT4 FAT atypical cadherin 4 0.218715
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.218374
SNX9 sorting nexin 9 0.216332
HBD hemoglobin, delta 0.213621
FZD1 frizzled class receptor 1 0.212608
NAV1 neuron navigator 1 0.211934
CD9 CD9 molecule 0.210925
EMG1 EMG1 N1-specific pseudouridine methyltransferase 0.210589
NES nestin 0.210589
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.209583
CCND2 cyclin D2 0.209248
CD86 CD86 molecule 0.207578
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.206913
NGF nerve growth factor (beta polypeptide) 0.205254
FBXL15 F-box and leucine-rich repeat protein 15 0.204923
ELOVL2 ELOVL fatty acid elongase 2 0.204593
WNT2 wingless-type MMTV integration site family member 2 0.20229
PTCH1 patched 1 0.20229
CCNA1 cyclin A1 0.201308
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.198709
ERH enhancer of rudimentary homolog (Drosophila) 0.197742
ALPPL2 alkaline phosphatase, placental-like 2 0.197099
ALPP alkaline phosphatase, placental 0.196779
ALPL alkaline phosphatase, liver/bone/kidney 0.196459
TICAM2 toll-like receptor adaptor molecule 2 0.196139
FOS FBJ murine osteosarcoma viral oncogene homolog 0.196139
IRX2 iroquois homeobox 2 0.19582
BMP4 bone morphogenetic protein 4 0.194865
SRPK1 SRSF protein kinase 1 0.194232
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.194232
CD83 CD83 molecule 0.193285
RRM1 ribonucleotide reductase M1 0.191408
ILK integrin-linked kinase 0.189859
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.189551
MCAM melanoma cell adhesion molecule 0.188938
CD24 CD24 molecule 0.186811
TESK1 testis-specific kinase 1 0.184128
PDGFB platelet-derived growth factor beta polypeptide 0.183835
CDX2 caudal type homeobox 2 0.183835
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 0.182375
NEGR1 neuronal growth regulator 1 0.180937
MAGEA3 melanoma antigen family A3 0.179239
BIRC5 baculoviral IAP repeat containing 5 0.17896
HMX2 H6 family homeobox 2 0.176215
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.175679
AMACR alpha-methylacyl-CoA racemase 0.174617
FN1 fibronectin 1 0.174354
CD33 CD33 molecule 0.173571
ESAM endothelial cell adhesion molecule 0.173057
GLIPR1 GLI pathogenesis-related 1 0.172291
ACTB actin, beta 0.171036
ENO1 enolase 1, (alpha) 0.169091
HLA-B major histocompatibility complex, class I, B 0.166995
STAT1 signal transducer and activator of transcription 1, 91kDa 0.166095
GAL3ST1 galactose-3-O-sulfotransferase 1 0.164786
CTNNBIP1 catenin, beta interacting protein 1 0.164571
SALL4 spalt-like transcription factor 4 0.163729
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.163317
S100A4 S100 calcium binding protein A4 0.162908
INS insulin 0.161716
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.161523
CDC73 cell division cycle 73 0.158266
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.148339
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.14769
PPP5C protein phosphatase 5, catalytic subunit 0.144698
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.144605
PPP6C protein phosphatase 6, catalytic subunit 0.144589
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.144511
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.144481
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.144429
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.144394
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.144371
WDR20 WD repeat domain 20 0.144111
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.144024
HES5 hes family bHLH transcription factor 5 0.143885
PPP4C protein phosphatase 4, catalytic subunit 0.143866
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.143828
TRAC T cell receptor alpha constant 0.140687
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.140384
IL6 interleukin 6 0.138879
ALK anaplastic lymphoma receptor tyrosine kinase 0.133148