nephrolithiasis Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description Formation of stones in the KIDNEY. (Experimental Factor Ontology, EFO_0004253)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:585
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Genes

28 genes associated with the disease nephrolithiasis in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
CLDN14 claudin 14 1.6622
RGS14 regulator of G-protein signaling 14 1.64114
DGKH diacylglycerol kinase, eta 1.45471
FAM188B family with sequence similarity 188, member B 1.19101
LRRC16A leucine rich repeat containing 16A 1.18117
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.13453
JAK3 Janus kinase 3 1.11647
CABLES1 Cdk5 and Abl enzyme substrate 1 1.09769
PKN1 protein kinase N1 1.09769
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.967203
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.935465
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.914528
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.868556
BCAS3 breast carcinoma amplified sequence 3 0.866472
CABP5 calcium binding protein 5 0.852796
MYOM1 myomesin 1 0.800256
MROH2A maestro heat-like repeat family member 2A 0.793562
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.780437
LRP2 low density lipoprotein receptor-related protein 2 0.778061
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 0.774882
PIAS4 protein inhibitor of activated STAT, 4 0.760692
FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 0.757946
OPTC opticin 0.756331
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 0.751885
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.716372
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 0.715357
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.708888
PFN3 profilin 3 0.674941