nephrosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

362 genes co-occuring with the disease nephrosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.82592
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 2.68734
ALB albumin 2.55007
LYZ lysozyme 1.99733
CD2AP CD2-associated protein 1.96567
CD79A CD79a molecule, immunoglobulin-associated alpha 1.89638
ACTN4 actinin, alpha 4 1.87377
KIRREL kin of IRRE like (Drosophila) 1.70998
ACE angiotensin I converting enzyme 1.66104
WT1 Wilms tumor 1 1.64442
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.6359
SYNPO synaptopodin 1.55557
PLCE1 phospholipase C, epsilon 1 1.55026
POMC proopiomelanocortin 1.42937
APOB apolipoprotein B 1.39652
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.36945
NPPA natriuretic peptide A 1.32236
REN renin 1.31275
PLA2R1 phospholipase A2 receptor 1, 180kDa 1.29396
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 1.28348
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.26909
RARA retinoic acid receptor, alpha 1.21522
LPA lipoprotein, Lp(a) 1.19964
CMIP c-Maf inducing protein 1.19532
TF transferrin 1.15325
B2M beta-2-microglobulin 1.13585
MPV17 MpV17 mitochondrial inner membrane protein 1.13289
FN1 fibronectin 1 1.10889
LPL lipoprotein lipase 1.10426
PROS1 protein S (alpha) 1.0753
FBXL20 F-box and leucine-rich repeat protein 20 1.0732
MYO1E myosin IE 1.07068
APOE apolipoprotein E 1.05429
PTPRO protein tyrosine phosphatase, receptor type, O 1.04546
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.04167
ADCK4 aarF domain containing kinase 4 1.03577
STOM stomatin 1.02945
CABIN1 calcineurin binding protein 1 1.02777
AQP2 aquaporin 2 (collecting duct) 1.02355
APOA1 apolipoprotein A-I 1.01554
LCAT lecithin-cholesterol acyltransferase 0.964567
INF2 inverted formin, FH2 and WH2 domain containing 0.963309
SDC2 syndecan 2 0.950352
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.933727
TGFB1 transforming growth factor, beta 1 0.93207
AFP alpha-fetoprotein 0.925865
PLG plasminogen 0.921736
LRP2 low density lipoprotein receptor-related protein 2 0.917199
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.892948
TJP1 tight junction protein 1 0.892129
COQ6 coenzyme Q6 monooxygenase 0.891718
EDA ectodysplasin A 0.890488
F12 coagulation factor XII (Hageman factor) 0.890078
F2 coagulation factor II (thrombin) 0.88475
TNS2 tensin 2 0.875329
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.868777
KIRREL3 kin of IRRE like 3 (Drosophila) 0.867959
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.866321
F9 coagulation factor IX 0.863865
DDN dendrin 0.862228
C3 complement component 3 0.849945
GC group-specific component (vitamin D binding protein) 0.834788
GNS glucosamine (N-acetyl)-6-sulfatase 0.833148
SOD2 superoxide dismutase 2, mitochondrial 0.822488
VEGFA vascular endothelial growth factor A 0.822488
ZHX1 zinc fingers and homeoboxes 1 0.80977
LMX1B LIM homeobox transcription factor 1, beta 0.792541
AVP arginine vasopressin 0.791311
ALPPL2 alkaline phosphatase, placental-like 2 0.788442
ALPP alkaline phosphatase, placental 0.788033
ALPL alkaline phosphatase, liver/bone/kidney 0.787213
PLA2G1B phospholipase A2, group IB (pancreas) 0.782298
F3 coagulation factor III (thromboplastin, tissue factor) 0.780251
CD4 CD4 molecule 0.771661
IL2RA interleukin 2 receptor, alpha 0.771252
CAT catalase 0.766351
IL13 interleukin 13 0.757786
APOA2 apolipoprotein A-II 0.756564
SAA1 serum amyloid A1 0.743547
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.741111
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 0.713601
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.710378
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.708767
F8 coagulation factor VIII, procoagulant component 0.70434
KIRREL2 kin of IRRE like 2 (Drosophila) 0.702732
CD19 CD19 molecule 0.690293
PTH parathyroid hormone 0.681096
ANGPTL4 angiopoietin-like 4 0.679898
ZHX3 zinc fingers and homeoboxes 3 0.674315
F5 coagulation factor V (proaccelerin, labile factor) 0.672722
TREH trehalase (brush-border membrane glycoprotein) 0.672324
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 0.648138
IL2 interleukin 2 0.639463
HPX hemopexin 0.630813
CD44 CD44 molecule (Indian blood group) 0.615138
GPX1 glutathione peroxidase 1 0.612011
GPX5 glutathione peroxidase 5 0.609276
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.606152
GPX4 glutathione peroxidase 4 0.606152
GZF1 GDNF-inducible zinc finger protein 1 0.60303
LAMA5 laminin, alpha 5 0.59952
SPP1 secreted phosphoprotein 1 0.594064
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 0.587444
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.585887
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.570718
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.569163
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.558285
CD68 CD68 molecule 0.547419
CD80 CD80 molecule 0.541992
CTXN1 cortexin 1 0.538506
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.535409
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.533088
INS insulin 0.530768
CYCS cytochrome c, somatic 0.529222
IL36A interleukin 36, alpha 0.526904
PCNA proliferating cell nuclear antigen 0.521117
IQGAP1 IQ motif containing GTPase activating protein 1 0.51534
VWF von Willebrand factor 0.512264
TNF tumor necrosis factor 0.504207
SGK1 serum/glucocorticoid regulated kinase 1 0.500761
GCA grancalcin, EF-hand calcium binding protein 0.499231
HLA-A major histocompatibility complex, class I, A 0.496175
PPOX protoporphyrinogen oxidase 0.495411
COX5A cytochrome c oxidase subunit Va 0.495411
GGT1 gamma-glutamyltransferase 1 0.493885
CRP C-reactive protein, pentraxin-related 0.493122
PLAT plasminogen activator, tissue 0.492359
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.491978
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.483604
SAA2 serum amyloid A2 0.482464
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.47753
LCN2 lipocalin 2 0.471468
HP haptoglobin 0.471468
RRBP1 ribosome binding protein 1 0.469197
AFM afamin 0.468063
MGP matrix Gla protein 0.467306
HPR haptoglobin-related protein 0.465416
IL4 interleukin 4 0.460506
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.459373
FTH1 ferritin, heavy polypeptide 1 0.457487
STAG1 stromal antigen 1 0.455601
IGSF5 immunoglobulin superfamily, member 5 0.455601
AQP3 aquaporin 3 (Gill blood group) 0.455224
PTPRU protein tyrosine phosphatase, receptor type, U 0.453339
MME membrane metallo-endopeptidase 0.452208
TTR transthyretin 0.448817
APOC3 apolipoprotein C-III 0.443547
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.440162
CORIN corin, serine peptidase 0.437154
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.436402
APOL1 apolipoprotein L, 1 0.430393
SEBOX SEBOX homeobox 0.429266
CFP complement factor properdin 0.42814
COQ4 coenzyme Q4 0.425514
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.424389
SYNJ1 synaptojanin 1 0.419892
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.418768
MEFV Mediterranean fever 0.418019
ACHE acetylcholinesterase (Yt blood group) 0.415773
SOCS4 suppressor of cytokine signaling 4 0.415398
IGLV1-51 immunoglobulin lambda variable 1-51 0.414276
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.410909
EZR ezrin 0.409414
IGF1 insulin-like growth factor 1 (somatomedin C) 0.409414
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.407919
CST3 cystatin C 0.406425
FTL ferritin, light polypeptide 0.404931
THBD thrombomodulin 0.402318
IFNA1 interferon, alpha 1 0.400453
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 0.396725
CCL2 chemokine (C-C motif) ligand 2 0.390397
CSN1S1 casein alpha s1 0.389281
MIR192 microRNA 192 0.388166
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.380739
HAVCR1 hepatitis A virus cellular receptor 1 0.378514
TBX1 T-box 1 0.377402
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.377402
SNX16 sorting nexin 16 0.375179
DNAH8 dynein, axonemal, heavy chain 8 0.371107
SCO1 SCO1 cytochrome c oxidase assembly protein 0.370737
RNASEH2A ribonuclease H2, subunit A 0.368518
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.368518
CP ceruloplasmin (ferroxidase) 0.362978
THY1 Thy-1 cell surface antigen 0.362609
IL1B interleukin 1, beta 0.361133
SH3GL2 SH3-domain GRB2-like 2 0.359289
NARS asparaginyl-tRNA synthetase 0.355972
SCARB1 scavenger receptor class B, member 1 0.354868
LCA10 lung carcinoma-associated 10 0.354499
IL18 interleukin 18 0.353763
AMOTL1 angiomotin like 1 0.353395
HBE1 hemoglobin, epsilon 1 0.341639
COQ9 coenzyme Q9 0.338341
COL4A5 collagen, type IV, alpha 5 0.335778
PBX4 pre-B-cell leukemia homeobox 4 0.331756
XDH xanthine dehydrogenase 0.33066
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.33066
RORC RAR-related orphan receptor C 0.330295
SREBF2 sterol regulatory element binding transcription factor 2 0.32701
PAX2 paired box 2 0.326646
PLAU plasminogen activator, urokinase 0.325187
KNG1 kininogen 1 0.324823
COL4A4 collagen, type IV, alpha 4 0.323002
CFI complement factor I 0.322273
BCHE butyrylcholinesterase 0.321181
NEIL1 nei endonuclease VIII-like 1 (E. coli) 0.319363
PTPRC protein tyrosine phosphatase, receptor type, C 0.314278
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.307757
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.305226
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.304503
FOXP3 forkhead box P3 0.302698
GUSB glucuronidase, beta 0.301976
MPO myeloperoxidase 0.301976
MN1 meningioma (disrupted in balanced translocation) 1 0.299092
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.298731
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.298011
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.295492
ADIPOQ adiponectin, C1Q and collagen domain containing 0.294772
GSTK1 glutathione S-transferase kappa 1 0.289744
PITPNB phosphatidylinositol transfer protein, beta 0.289386
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 0.289027
IGFBP3 insulin-like growth factor binding protein 3 0.288668
HPSE heparanase 0.287593
SH3GL3 SH3-domain GRB2-like 3 0.286877
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.282225
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.279011
IGHA1 immunoglobulin heavy constant alpha 1 0.277584
COX6C cytochrome c oxidase subunit VIc 0.27687
PF4 platelet factor 4 0.276514
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.274732
AMBP alpha-1-microglobulin/bikunin precursor 0.274021
SDK1 sidekick cell adhesion molecule 1 0.273664
TNC tenascin C 0.272953
DNM2 dynamin 2 0.272597
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.266913
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.265494
LDLR low density lipoprotein receptor 0.261952
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.261599
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.260538
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.259477
AGTR1 angiotensin II receptor, type 1 0.255946
IL6 interleukin 6 0.255241
PRSS8 protease, serine, 8 0.254536
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.253479
CETP cholesteryl ester transfer protein, plasma 0.24996
FYN FYN proto-oncogene, Src family tyrosine kinase 0.24996
CXCL8 chemokine (C-X-C motif) ligand 8 0.248203
TIMP1 TIMP metallopeptidase inhibitor 1 0.246448
OLFM1 olfactomedin 1 0.246098
GLCCI1 glucocorticoid induced 1 0.241895
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.240148
MYH9 myosin, heavy chain 9, non-muscle 0.23945
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.237706
NFRKB nuclear factor related to kappaB binding protein 0.23666
STS steroid sulfatase (microsomal), isozyme S 0.234573
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.234225
CFB complement factor B 0.230063
RAB5B RAB5B, member RAS oncogene family 0.228333
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.226607
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.225229
ILK integrin-linked kinase 0.22454
ITSN2 intersectin 2 0.218374
IFNA2 interferon, alpha 2 0.217012
ACTB actin, beta 0.216672
AVPR2 arginine vasopressin receptor 2 0.212945
THEM5 thioesterase superfamily member 5 0.211597
APOC2 apolipoprotein C-II 0.211261
AHSG alpha-2-HS-glycoprotein 0.209583
CFH complement factor H 0.208914
LCMT2 leucine carboxyl methyltransferase 2 0.206248
CGN cingulin 0.203933
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.200656
POU6F2 POU class 6 homeobox 2 0.199356
WEE1 WEE1 G2 checkpoint kinase 0.199033
DGCR6 DiGeorge syndrome critical region gene 6 0.19742
HRG histidine-rich glycoprotein 0.196459
MB myoglobin 0.190476
ACTG1 actin gamma 1 0.190476
CXCL16 chemokine (C-X-C motif) ligand 16 0.18621
BGLAP bone gamma-carboxyglutamate (gla) protein 0.185313
LAP3 leucine aminopeptidase 3 0.18472
MGAM maltase-glucoamylase 0.184128
DCAF7 DDB1 and CUL4 associated factor 7 0.184128
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.183248
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.180084
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.180084
NPPC natriuretic peptide C 0.176757
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.175679
PRTN3 proteinase 3 0.174881
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.174093
PRKD2 protein kinase D2 0.173571
COG2 component of oligomeric golgi complex 2 0.172799
CANX calnexin 0.172544
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.171286
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.171036
FAT1 FAT atypical cadherin 1 0.170299
ADA adenosine deaminase 0.168617
GSN gelsolin 0.168617
NEBL nebulette 0.168148
ALG10 ALG10, alpha-1,2-glucosyltransferase 0.167682
KIF27 kinesin family member 27 0.166095
SCARB2 scavenger receptor class B, member 2 0.165874
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.164786
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.163523
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.162505
AMPD2 adenosine monophosphate deaminase 2 0.161331
ICAM1 intercellular adhesion molecule 1 0.159658
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.158778
PCSK9 proprotein convertase subtilisin/kexin type 9 0.158605
LAMB1 laminin, beta 1 0.146389
MX2 MX dynamin-like GTPase 2 0.143166
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 0.14281
EFNB1 ephrin-B1 0.142762
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 0.142132
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.142123
UBC ubiquitin C 0.141896
NID1 nidogen 1 0.141876
RPS27A ribosomal protein S27a 0.141779
GPC5 glypican 5 0.141401
ETV4 ets variant 4 0.141131
UBB ubiquitin B 0.141114
CA10 carbonic anhydrase X 0.140205
SPTBN1 spectrin, beta, non-erythrocytic 1 0.140076
MOGS mannosyl-oligosaccharide glucosidase 0.139847
CD14 CD14 molecule 0.139809
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.139725
COL5A1 collagen, type V, alpha 1 0.138914
RRM1 ribonucleotide reductase M1 0.138806
LIG3 ligase III, DNA, ATP-dependent 0.138539
APLP1 amyloid beta (A4) precursor-like protein 1 0.138377
MX1 MX dynamin-like GTPase 1 0.136568
LAMC2 laminin, gamma 2 0.136391
PSAP prosaposin 0.136275
PAEP progestagen-associated endometrial protein 0.135623
TREX1 three prime repair exonuclease 1 0.135567
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.135481
IL10 interleukin 10 0.135129
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.134554
CD151 CD151 molecule (Raph blood group) 0.134538
ARRB2 arrestin, beta 2 0.13399
HMGA2 high mobility group AT-hook 2 0.133462
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.133111
CD276 CD276 molecule 0.132408
CTNND1 catenin (cadherin-associated protein), delta 1 0.132037
DNM3 dynamin 3 0.128658
AFF2 AF4/FMR2 family, member 2 0.128573
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.12843
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 0.128342
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.128283
HAND1 heart and neural crest derivatives expressed 1 0.128018
FMN1 formin 1 0.127957
SOAT2 sterol O-acyltransferase 2 0.127866
WTIP Wilms tumor 1 interacting protein 0.127715
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.127592
LAMB2 laminin, beta 2 (laminin S) 0.127529
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.127467
LVRN laeverin 0.127185
IFNB1 interferon, beta 1, fibroblast 0.127088
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.126926
IGF2R insulin-like growth factor 2 receptor 0.126764
LEP leptin 0.126698
ZNF266 zinc finger protein 266 0.126564