ner Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). (Gene Ontology, GO_0006289)
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Genes

32 genes co-occuring with the biological term ner in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CCNH cyclin H
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CUL4A cullin 4A
CUL4B cullin 4B
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
E2F1 E2F transcription factor 1
EIF3A eukaryotic translation initiation factor 3, subunit A
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
GLI1 GLI family zinc finger 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
H2AFX H2A histone family, member X
HMGB1 high mobility group box 1
JUN jun proto-oncogene
MAPK14 mitogen-activated protein kinase 14
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR192 microRNA 192
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
PARP1 poly (ADP-ribose) polymerase 1
RNF2 ring finger protein 2
RPA1 replication protein A1, 70kDa
SIRT1 sirtuin 1
TP63 tumor protein p63
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCP valosin containing protein
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1