netilmicin-3524 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the netilmicin-3524 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADAM20 ADAM metallopeptidase domain 20
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALDOB aldolase B, fructose-bisphosphate
AMACR alpha-methylacyl-CoA racemase
ARTN artemin
ATF6B activating transcription factor 6 beta
BMP1 bone morphogenetic protein 1
C16ORF70 chromosome 16 open reading frame 70
C6ORF10 chromosome 6 open reading frame 10
C7ORF26 chromosome 7 open reading frame 26
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CADM3 cell adhesion molecule 3
CASR calcium-sensing receptor
CELP carboxyl ester lipase pseudogene
CFHR4 complement factor H-related 4
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNTN5 contactin 5
CORO2B coronin, actin binding protein, 2B
CSHL1 chorionic somatomammotropin hormone-like 1
CXXC4 CXXC finger protein 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ERO1LB ERO1-like beta (S. cerevisiae)
FAM131A family with sequence similarity 131, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCMR Fc fragment of IgM receptor
FGF2 fibroblast growth factor 2 (basic)
FKBP10 FK506 binding protein 10, 65 kDa
FYB FYN binding protein
GBP1 guanylate binding protein 1, interferon-inducible
GDF5 growth differentiation factor 5
GNAS GNAS complex locus
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H4E histone cluster 1, H4e
HOXA4 homeobox A4
HSF4 heat shock transcription factor 4
IFT54 intraflagellar transport 54
IL4R interleukin 4 receptor
IRF5 interferon regulatory factor 5
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLK2 kallikrein-related peptidase 2
KRT16 keratin 16, type I
LEFTY2 left-right determination factor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMCH1 LIM and calponin homology domains 1
LINC00260 long intergenic non-protein coding RNA 260
LINC00341 long intergenic non-protein coding RNA 341
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAP1A microtubule-associated protein 1A
MAPK7 mitogen-activated protein kinase 7
MYL10 myosin, light chain 10, regulatory
NCF1C neutrophil cytosolic factor 1C pseudogene
NR4A1 nuclear receptor subfamily 4, group A, member 1
OGFR opioid growth factor receptor
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OSBP2 oxysterol binding protein 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11Y protocadherin 11 Y-linked
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PER2 period circadian clock 2
PIDD1 p53-induced death domain protein 1
PKNOX2 PBX/knotted 1 homeobox 2
PLXNA2 plexin A2
PLXNC1 plexin C1
PYY peptide YY
RAB35 RAB35, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARG retinoic acid receptor, gamma
RETN resistin
RHEB Ras homolog enriched in brain
RUNDC3A RUN domain containing 3A
SARDH sarcosine dehydrogenase
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SEZ6L seizure related 6 homolog (mouse)-like
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SNX13 sorting nexin 13
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SYBU syntabulin (syntaxin-interacting)
TBR1 T-box, brain, 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM2 transglutaminase 2
TMPRSS4 transmembrane protease, serine 4
TNK2 tyrosine kinase, non-receptor, 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSKS testis-specific serine kinase substrate
XCR1 chemokine (C motif) receptor 1
ZNF235 zinc finger protein 235
ZNF358 zinc finger protein 358
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCAS1 breast carcinoma amplified sequence 1
C12ORF4 chromosome 12 open reading frame 4
CADPS2 Ca++-dependent secretion activator 2
CAPRIN2 caprin family member 2
CCDC186 coiled-coil domain containing 186
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CLCN2 chloride channel, voltage-sensitive 2
CLDN15 claudin 15
CST6 cystatin E/M
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DUSP8 dual specificity phosphatase 8
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
EXO5 exonuclease 5
FKBP5 FK506 binding protein 5
FRK fyn-related Src family tyrosine kinase
GALK1 galactokinase 1
GBP2 guanylate binding protein 2, interferon-inducible
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPATCH2L G patch domain containing 2-like
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
IER3IP1 immediate early response 3 interacting protein 1
IFT81 intraflagellar transport 81
IPP intracisternal A particle-promoted polypeptide
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KIF13A kinesin family member 13A
KLC2 kinesin light chain 2
KLHL2 kelch-like family member 2
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LOC100287590 uncharacterized LOC100287590
MAGEA6 melanoma antigen family A6
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MORC3 MORC family CW-type zinc finger 3
MTERF1 mitochondrial transcription termination factor 1
MVD mevalonate (diphospho) decarboxylase
N4BP3 NEDD4 binding protein 3
NLRX1 NLR family member X1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POPDC3 popeye domain containing 3
PRPH peripherin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RASL11B RAS-like, family 11, member B
RPAIN RPA interacting protein
RPAP1 RNA polymerase II associated protein 1
RUSC2 RUN and SH3 domain containing 2
S100A4 S100 calcium binding protein A4
SAV1 salvador family WW domain containing protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SETD8 SET domain containing (lysine methyltransferase) 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STX1A syntaxin 1A (brain)
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBCCD1 TBCC domain containing 1
TCP10 t-complex 10
TCTA T-cell leukemia translocation altered
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM242 transmembrane protein 242
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USB1 U6 snRNA biogenesis 1
WLS wntless Wnt ligand secretion mediator
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB39 zinc finger and BTB domain containing 39
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516
ZNF532 zinc finger protein 532
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747