neuroblastoma Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation.|A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)|A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome (MeSH). (Experimental Factor Ontology, EFO_0000621)
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Genes

569 genes co-occuring with the biological term neuroblastoma in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACHE acetylcholinesterase (Yt blood group)
ACKR3 atypical chemokine receptor 3
ACP1 acid phosphatase 1, soluble
ACVR2A activin A receptor, type IIA
ACY1 aminoacylase 1
ADAM17 ADAM metallopeptidase domain 17
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
AGER advanced glycosylation end product-specific receptor
AGGF1 angiogenic factor with G patch and FHA domains 1
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AHR aryl hydrocarbon receptor
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALCAM activated leukocyte cell adhesion molecule
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANG angiogenin, ribonuclease, RNase A family, 5
APAF1 apoptotic peptidase activating factor 1
APITD1 apoptosis-inducing, TAF9-like domain 1
APP amyloid beta (A4) precursor protein
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARID1A AT rich interactive domain 1A (SWI-like)
ARID1B AT rich interactive domain 1B (SWI1-like)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB1 arrestin, beta 1
ASCL1 achaete-scute family bHLH transcription factor 1
ASPH aspartate beta-hydroxylase
ATF2 activating transcription factor 2
ATF4 activating transcription factor 4
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATRX alpha thalassemia/mental retardation syndrome X-linked
ATXN2 ataxin 2
ATXN3 ataxin 3
AURKA aurora kinase A
AURKB aurora kinase B
AXL AXL receptor tyrosine kinase
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GAT1 beta-1,3-glucuronyltransferase 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BACE1 beta-site APP-cleaving enzyme 1
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCYRN1 brain cytoplasmic RNA 1
BDNF brain-derived neurotrophic factor
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BMI1 BMI1 proto-oncogene, polycomb ring finger
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTG2 BTG family, member 2
C3 complement component 3
CACYBP calcyclin binding protein
CADM1 cell adhesion molecule 1
CALB2 calbindin 2
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMTA1 calmodulin binding transcription activator 1
CASC15 cancer susceptibility candidate 15 (non-protein coding)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CASZ1 castor zinc finger 1
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD24 CD24 molecule
CD276 CD276 molecule
CD44 CD44 molecule (Indian blood group)
CDK16 cyclin-dependent kinase 16
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN3 cyclin-dependent kinase inhibitor 3
CERK ceramide kinase
CES2 carboxylesterase 2
CFL1 cofilin 1 (non-muscle)
CGB5 chorionic gonadotropin, beta polypeptide 5
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHD5 chromodomain helicase DNA binding protein 5
CHEK1 checkpoint kinase 1
CHRM2 cholinergic receptor, muscarinic 2
CLU clusterin
CNTF ciliary neurotrophic factor
COMT catechol-O-methyltransferase
CRABP2 cellular retinoic acid binding protein 2
CREB1 cAMP responsive element binding protein 1
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTAG1B cancer/testis antigen 1B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYTL1 cytokine-like 1
DCX doublecortin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT3 DNA-damage-inducible transcript 3
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DEGS1 delta(4)-desaturase, sphingolipid 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DHCR24 24-dehydrocholesterol reductase
DICER1 dicer 1, ribonuclease type III
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPYSL2 dihydropyrimidinase-like 2
DPYSL3 dihydropyrimidinase-like 3
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DROSHA drosha, ribonuclease type III
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELAVL1 ELAV like RNA binding protein 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELK1 ELK1, member of ETS oncogene family
ENG endoglin
ENO2 enolase 2 (gamma, neuronal)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPAS1 endothelial PAS domain protein 1
EPHA2 EPH receptor A2
EPO erythropoietin
ERAS ES cell expressed Ras
ERBB3 erb-b2 receptor tyrosine kinase 3
ERVW-1 endogenous retrovirus group W, member 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM107A family with sequence similarity 107, member A
FAM134C family with sequence similarity 134, member C
FAM163A family with sequence similarity 163, member A
FAS Fas cell surface death receptor
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FFAR1 free fatty acid receptor 1
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FHIT fragile histidine triad
FHL2 four and a half LIM domains 2
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLOT1 flotillin 1
FLT1 fms-related tyrosine kinase 1
FNTB farnesyltransferase, CAAX box, beta
FOXA1 forkhead box A1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXR1 forkhead box R1
FXN frataxin
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD1 frizzled class receptor 1
FZD6 frizzled class receptor 6
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAL galanin/GMAP prepropeptide
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GALR2 galanin receptor 2
GAS7 growth arrest-specific 7
GCLC glutamate-cysteine ligase, catalytic subunit
GDNF glial cell derived neurotrophic factor
GLI1 GLI family zinc finger 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNAS GNAS complex locus
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC3 glypican 3
GRP gastrin-releasing peptide
GRPR gastrin-releasing peptide receptor
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HAND2 heart and neural crest derivatives expressed 2
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
HCRTR1 hypocretin (orexin) receptor 1
HDAC10 histone deacetylase 10
HDAC2 histone deacetylase 2
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HDAC8 histone deacetylase 8
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST2H3A histone cluster 2, H3a
HIST4H4 histone cluster 4, H4
HLA-G major histocompatibility complex, class I, G
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HOMER1 homer scaffolding protein 1
HOXC11 homeobox C11
HOXC6 homeobox C6
HOXC9 homeobox C9
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTRA1 HtrA serine peptidase 1
ICAM2 intercellular adhesion molecule 2
ICMT isoprenylcysteine carboxyl methyltransferase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL1B interleukin 1, beta
IL24 interleukin 24
IL6 interleukin 6
IL6R interleukin 6 receptor
ILK integrin-linked kinase
INA internexin neuronal intermediate filament protein, alpha
INHBA inhibin, beta A
IRF1 interferon regulatory factor 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITM2B integral membrane protein 2B
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDM1A lysine (K)-specific demethylase 1A
KDM3A lysine (K)-specific demethylase 3A
KDR kinase insert domain receptor
KIDINS220 kinase D-interacting substrate, 220kDa
KIF1B kinesin family member 1B
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT19 keratin 19, type I
L1CAM L1 cell adhesion molecule
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS7 lectin, galactoside-binding, soluble, 7
LIF leukemia inhibitory factor
LIN28B lin-28 homolog B (C. elegans)
LINC00467 long intergenic non-protein coding RNA 467
LMNA lamin A/C
LMO1 LIM domain only 1 (rhombotin 1)
LMO3 LIM domain only 3 (rhombotin-like 2)
LRP10 low density lipoprotein receptor-related protein 10
LRRK2 leucine-rich repeat kinase 2
LRRN1 leucine rich repeat neuronal 1
LRRN3 leucine rich repeat neuronal 3
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MADD MAP-kinase activating death domain
MAGEA1 melanoma antigen family A1
MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
MAP2 microtubule-associated protein 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MATK megakaryocyte-associated tyrosine kinase
MBD2 methyl-CpG binding domain protein 2
MCL1 myeloid cell leukemia 1
MCM7 minichromosome maintenance complex component 7
MCRS1 microspherule protein 1
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEN1 multiple endocrine neoplasia I
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MIR101-1 microRNA 101-1
MIR124-1 microRNA 124-1
MIR128-1 microRNA 128-1
MIR128-2 microRNA 128-2
MIR137 microRNA 137
MIR138-1 microRNA 138-1
MIR143 microRNA 143
MIR145 microRNA 145
MIR152 microRNA 152
MIR15A microRNA 15a
MIR181A1 microRNA 181a-1
MIR181C microRNA 181c
MIR190A microRNA 190a
MIR192 microRNA 192
MIR200B microRNA 200b
MIR202 microRNA 202
MIR206 microRNA 206
MIR21 microRNA 21
MIR210 microRNA 210
MIR27B microRNA 27b
MIR29A microRNA 29a
MIR329-1 microRNA 329-1
MIR335 microRNA 335
MIR338 microRNA 338
MIR34A microRNA 34a
MIR363 microRNA 363
MIR380 microRNA 380
MIR410 microRNA 410
MIR421 microRNA 421
MIR432 microRNA 432
MIR487B microRNA 487b
MIR497 microRNA 497
MIR516A1 microRNA 516a-1
MIR516A2 microRNA 516a-2
MIR7-1 microRNA 7-1
MIR92A1 microRNA 92a-1
MIRLET7A1 microRNA let-7a-1
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MXI1 MAX interactor 1, dimerization protein
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYCNUT MYCN upstream transcript (non-protein coding)
MYEOV myeloma overexpressed
NAV2 neuron navigator 2
NBAS neuroblastoma amplified sequence
NBAT1 neuroblastoma associated transcript 1
NCAM1 neural cell adhesion molecule 1
NCF2 neutrophil cytosolic factor 2
NCOA7 nuclear receptor coactivator 7
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEGR1 neuronal growth regulator 1
NES nestin
NEU4 sialidase 4
NEUROD1 neuronal differentiation 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NHLH2 nescient helix loop helix 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NPY neuropeptide Y
NPY2R neuropeptide Y receptor Y2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRF1 nuclear respiratory factor 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OAZ2 ornithine decarboxylase antizyme 2
ODC1 ornithine decarboxylase 1
OPRM1 opioid receptor, mu 1
OTX2 orthodenticle homeobox 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARK7 parkinson protein 7
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX3 paired box 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPN podoplanin
PEA15 phosphoprotein enriched in astrocytes 15
PER1 period circadian clock 1
PGK1 phosphoglycerate kinase 1
PHOX2A paired-like homeobox 2a
PHOX2B paired-like homeobox 2b
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAT plasminogen activator, tissue
PLK1 polo-like kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNPLA6 patatin-like phospholipase domain containing 6
POU4F2 POU class 4 homeobox 2
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRAF2 PRA1 domain family, member 2
PRAME preferentially expressed antigen in melanoma
PRDM2 PR domain containing 2, with ZNF domain
PREP prolyl endopeptidase
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRNP prion protein
PROK1 prokineticin 1
PROM1 prominin 1
PROX1 prospero homeobox 1
PRPH peripherin
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTAFR platelet-activating factor receptor
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRD protein tyrosine phosphatase, receptor type, D
PVT1 Pvt1 oncogene (non-protein coding)
PYCARD PYD and CARD domain containing
QSOX1 quiescin Q6 sulfhydryl oxidase 1
QSOX2 quiescin Q6 sulfhydryl oxidase 2
RAB15 RAB15, member RAS oncogene family
RAE1 ribonucleic acid export 1
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RASSF6 Ras association (RalGDS/AF-6) domain family member 6
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RB1 retinoblastoma 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELN reelin
RET ret proto-oncogene
RRP1 ribosomal RNA processing 1
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
S100A4 S100 calcium binding protein A4
SCG2 secretogranin II
SCGB3A1 secretoglobin, family 3A, member 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHH sonic hedgehog
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A10 solute carrier family 30, member 10
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
SMAD1 SMAD family member 1
SMAD7 SMAD family member 7
SMN1 survival of motor neuron 1, telomeric
SNAI2 snail family zinc finger 2
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
SSTR2 somatostatin receptor 2
STAG2 stromal antigen 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STC2 stanniocalcin 2
STMN1 stathmin 1
SULF2 sulfatase 2
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SYT1 synaptotagmin I
TAC1 tachykinin, precursor 1
TACR2 tachykinin receptor 2
TCF3 transcription factor 3
TENM4 teneurin transmembrane protein 4
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
TH tyrosine hydroxylase
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLX2 T-cell leukemia homeobox 2
TMSB15A thymosin beta 15a
TNF tumor necrosis factor
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP73 tumor protein p73
TRIM16 tripartite motif containing 16
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTR transthyretin
UBE2N ubiquitin-conjugating enzyme E2N
UBE4B ubiquitination factor E4B
UNC5D unc-5 homolog D (C. elegans)
URGCP upregulator of cell proliferation
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VIP vasoactive intestinal peptide
VSNL1 visinin-like 1
WEE1 WEE1 G2 checkpoint kinase
WFS1 Wolfram syndrome 1 (wolframin)
WIF1 WNT inhibitory factor 1
WNT1 wingless-type MMTV integration site family, member 1
WNT2 wingless-type MMTV integration site family member 2
WNT3 wingless-type MMTV integration site family, member 3
WNT4 wingless-type MMTV integration site family, member 4
WSB1 WD repeat and SOCS box containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB17 zinc finger and BTB domain containing 17
ZMAT3 zinc finger, matrin-type 3
ZMYND10 zinc finger, MYND-type containing 10
ZNF423 zinc finger protein 423
ZNF622 zinc finger protein 622
ZSCAN10 zinc finger and SCAN domain containing 10