neurodegeneration Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description a retrogressive impairment of function or destruction of neural tissue (Mammalian Phenotype Ontology, MP_0002229)
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Genes

56 proteins co-occuring with the biological term neurodegeneration in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
ATXN1 ataxin 1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASP6 caspase 6, apoptosis-related cysteine peptidase
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CLCN3 chloride channel, voltage-sensitive 3
CREB1 cAMP responsive element binding protein 1
DLG4 discs, large homolog 4 (Drosophila)
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNM1L dynamin 1-like
E2F4 E2F transcription factor 4, p107/p130-binding
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HTRA2 HtrA serine peptidase 2
HTT huntingtin
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MARK2 MAP/microtubule affinity-regulating kinase 2
MEF2A myocyte enhancer factor 2A
MEF2D myocyte enhancer factor 2D
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PINK1 PTEN induced putative kinase 1
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PTK2B protein tyrosine kinase 2 beta
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TARDBP TAR DNA binding protein
TP53 tumor protein p53
TUBB tubulin, beta class I
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
WWOX WW domain containing oxidoreductase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6