neurofilament Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter. (Gene Ontology, GO_0005883)
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Genes

312 proteins co-occuring with the neurofilament cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NEFH neurofilament, heavy polypeptide 3.10351
NEFM neurofilament, medium polypeptide 2.90004
ENO2 enolase 2 (gamma, neuronal) 2.62166
SYP synaptophysin 2.51081
NEFL neurofilament, light polypeptide 2.14059
GFAP glial fibrillary acidic protein 2.10347
MBP myelin basic protein 2.01484
NES nestin 1.9855
MAP2 microtubule-associated protein 2 1.97132
INA internexin neuronal intermediate filament protein, alpha 1.85868
NGF nerve growth factor (beta polypeptide) 1.84019
TH tyrosine hydroxylase 1.81512
CALCA calcitonin-related polypeptide alpha 1.80373
TAC1 tachykinin, precursor 1 1.66659
B3GAT1 beta-1,3-glucuronyltransferase 1 1.65032
CALB1 calbindin 1, 28kDa 1.63182
GAN gigaxonin 1.56389
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.5367
CDK5 cyclin-dependent kinase 5 1.51976
GAP43 growth associated protein 43 1.51356
CALB2 calbindin 2 1.51356
CHGA chromogranin A 1.50961
PVALB parvalbumin 1.49267
MAPT microtubule-associated protein tau 1.48758
CHAT choline O-acetyltransferase 1.48588
DES desmin 1.39294
ACHE acetylcholinesterase (Yt blood group) 1.33413
SRRM1 serine/arginine repetitive matrix 1 1.32167
MAP1B microtubule-associated protein 1B 1.26974
NGFR nerve growth factor receptor 1.25548
NPY neuropeptide Y 1.2387
MAP4 microtubule-associated protein 4 1.23557
BDNF brain-derived neurotrophic factor 1.2288
DNM2 dynamin 2 1.22672
SST somatostatin 1.18184
NCAM1 neural cell adhesion molecule 1 1.17106
NTF3 neurotrophin 3 1.16799
GDNF glial cell derived neurotrophic factor 1.15876
FGF2 fibroblast growth factor 2 (basic) 1.13625
THY1 Thy-1 cell surface antigen 1.10409
NPS neuropeptide S 1.08374
VIP vasoactive intestinal peptide 1.07258
CD34 CD34 molecule 1.06701
S100B S100 calcium binding protein B 1.06195
SOD2 superoxide dismutase 2, mitochondrial 1.0423
MAG myelin associated glycoprotein 1.02032
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.02032
SYN1 synapsin I 0.985854
MOG myelin oligodendrocyte glycoprotein 0.942584
ASCL1 achaete-scute family bHLH transcription factor 1 0.936432
KRT20 keratin 20, type I 0.93596
CNTF ciliary neurotrophic factor 0.916243
MPZ myelin protein zero 0.899962
TUBA1A tubulin, alpha 1a 0.898109
ISL1 ISL LIM homeobox 1 0.884705
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.845155
CD99 CD99 molecule 0.845155
APP amyloid beta (A4) precursor protein 0.843778
PMP22 peripheral myelin protein 22 0.836892
ALPPL2 alkaline phosphatase, placental-like 2 0.809817
ALPL alkaline phosphatase, liver/bone/kidney 0.8089
ALPP alkaline phosphatase, placental 0.8089
CRYAB crystallin, alpha B 0.800187
EDA ectodysplasin A 0.79652
GAL galanin/GMAP prepropeptide 0.795604
CD68 CD68 molecule 0.779583
TUB tubby bipartite transcription factor 0.774558
OLIG2 oligodendrocyte lineage transcription factor 2 0.768171
POU4F1 POU class 4 homeobox 1 0.763617
PAX6 paired box 6 0.753623
HSPB1 heat shock 27kDa protein 1 0.75317
MB myoglobin 0.748189
NEUROD1 neuronal differentiation 1 0.747285
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.735565
SAG S-antigen; retina and pineal gland (arrestin) 0.730628
POMC proopiomelanocortin 0.720351
PHF1 PHD finger protein 1 0.71946
FN1 fibronectin 1 0.711908
NRCAM neuronal cell adhesion molecule 0.689013
DCX doublecortin 0.684207
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.676368
F8 coagulation factor VIII, procoagulant component 0.664232
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.6638
AIF1 allograft inflammatory factor 1 0.650869
RTN4 reticulon 4 0.645716
CAST calpastatin 0.641429
STMN2 stathmin 2 0.636723
GRP gastrin-releasing peptide 0.632024
MTMR2 myotubularin related protein 2 0.626057
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.614589
KRT7 keratin 7, type II 0.608241
PDYN prodynorphin 0.60655
PROS1 protein S (alpha) 0.606128
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.605284
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.604862
ATF3 activating transcription factor 3 0.600223
NEU2 sialidase 2 (cytosolic sialidase) 0.596855
PTPRC protein tyrosine phosphatase, receptor type, C 0.589714
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.588456
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.588456
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.588037
TRIM2 tripartite motif containing 2 0.588037
PNMT phenylethanolamine N-methyltransferase 0.58678
DSP desmoplakin 0.579669
GALC galactosylceramidase 0.571329
ACTB actin, beta 0.565092
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.563017
TP53 tumor protein p53 0.562602
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.556387
CSN1S1 casein alpha s1 0.54936
EWSR1 EWS RNA-binding protein 1 0.547297
NF2 neurofibromin 2 (merlin) 0.545648
SYNM synemin, intermediate filament protein 0.544823
PNPLA6 patatin-like phospholipase domain containing 6 0.544
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.543587
ACTG1 actin gamma 1 0.536183
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.532488
NTF4 neurotrophin 4 0.52675
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.525522
UBC ubiquitin C 0.523885
OPN4 opsin 4 0.523885
NF1 neurofibromin 1 0.523067
FOS FBJ murine osteosarcoma viral oncogene homolog 0.515308
RHO rhodopsin 0.509197
CAPN2 calpain 2, (m/II) large subunit 0.50879
HBA1 hemoglobin, alpha 1 0.505131
PRX periaxin 0.504724
GMFB glia maturation factor, beta 0.503099
HBA2 hemoglobin, alpha 2 0.499447
RPS27A ribosomal protein S27a 0.499042
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.499042
RCVRN recoverin 0.498636
UBB ubiquitin B 0.483273
CST3 cystatin C 0.479245
IGF1 insulin-like growth factor 1 (somatomedin C) 0.476429
JUN jun proto-oncogene 0.47442
GLUL glutamate-ammonia ligase 0.472813
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.466399
AFP alpha-fetoprotein 0.465198
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.463598
ALB albumin 0.458803
CAPN1 calpain 1, (mu/I) large subunit 0.446862
KIF5A kinesin family member 5A 0.446862
CEND1 cell cycle exit and neuronal differentiation 1 0.444482
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.438146
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.43538
SCN10A sodium channel, voltage gated, type X alpha subunit 0.434196
RGMA repulsive guidance molecule family member a 0.430253
VIM vimentin 0.429072
MLANA melan-A 0.421997
SOX10 SRY (sex determining region Y)-box 10 0.41886
SHH sonic hedgehog 0.418077
MNX1 motor neuron and pancreas homeobox 1 0.417294
KRT8 keratin 8, type II 0.41182
INS insulin 0.40675
SPRED1 sprouty-related, EVH1 domain containing 1 0.394323
POU4F2 POU class 4 homeobox 2 0.392388
AQP4 aquaporin 4 0.378507
MYOG myogenin (myogenic factor 4) 0.376586
MRAP melanocortin 2 receptor accessory protein 0.372749
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.372749
NRN1 neuritin 1 0.371216
RTN4R reticulon 4 receptor 0.370067
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.367006
GJB1 gap junction protein, beta 1, 32kDa 0.366241
APOE apolipoprotein E 0.365859
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.365477
PHOX2A paired-like homeobox 2a 0.364331
NEUROG1 neurogenin 1 0.361277
COX5A cytochrome c oxidase subunit Va 0.360896
GLB1 galactosidase, beta 1 0.360896
PPY pancreatic polypeptide 0.353282
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.349105
SDF4 stromal cell derived factor 4 0.347967
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.345692
CLDN1 claudin 1 0.341907
KRT18 keratin 18, type I 0.341907
DLX2 distal-less homeobox 2 0.341907
EGR2 early growth response 2 0.339639
CLDN7 claudin 7 0.337751
PCNA proliferating cell nuclear antigen 0.337373
DCTN1 dynactin 1 0.336996
ASMT acetylserotonin O-methyltransferase 0.336619
DNTT DNA nucleotidylexotransferase 0.335487
TNC tenascin C 0.333225
CNTN2 contactin 2 (axonal) 0.328332
TARDBP TAR DNA binding protein 0.326453
GJB6 gap junction protein, beta 6, 30kDa 0.324201
HSPA4 heat shock 70kDa protein 4 0.320077
DCAF8 DDB1 and CUL4 associated factor 8 0.320077
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.318953
SOX2 SRY (sex determining region Y)-box 2 0.316708
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.316334
NTS neurotensin 0.315586
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.314839
TSPO translocator protein (18kDa) 0.310358
TRGJP2 T cell receptor gamma joining P2 0.309613
ABHD17A abhydrolase domain containing 17A 0.309613
ABHD17AP1 abhydrolase domain containing 17A pseudogene 1 0.309613
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.308494
GSK3A glycogen synthase kinase 3 alpha 0.306632
GSK3B glycogen synthase kinase 3 beta 0.304399
CCK cholecystokinin 0.303283
SMN2 survival of motor neuron 2, centromeric 0.298826
BHLHE23 basic helix-loop-helix family, member e23 0.292157
KERA keratocan 0.288829
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.288091
GAST gastrin 0.280716
HSPA12A heat shock 70kDa protein 12A 0.275569
NEUROG2 neurogenin 2 0.272633
DST dystonin 0.271533
MAPK8 mitogen-activated protein kinase 8 0.267505
PROM1 prominin 1 0.266042
LYZ lysozyme 0.264581
TPH1 tryptophan hydroxylase 1 0.264215
GJA1 gap junction protein, alpha 1, 43kDa 0.26312
FGF1 fibroblast growth factor 1 (acidic) 0.26312
GCG glucagon 0.259473
S100P S100 calcium binding protein P 0.258016
PSEN1 presenilin 1 0.258016
NPY1R neuropeptide Y receptor Y1 0.257652
CXCL13 chemokine (C-X-C motif) ligand 13 0.256561
CDK4 cyclin-dependent kinase 4 0.256197
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 0.255107
NECAB1 N-terminal EF-hand calcium binding protein 1 0.252927
PRNP prion protein 0.250026
GLG1 golgi glycoprotein 1 0.248578
SBF2 SET binding factor 2 0.248578
CD44 CD44 molecule (Indian blood group) 0.247492
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.247492
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.24713
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.246769
RET ret proto-oncogene 0.245685
EFNA4 ephrin-A4 0.245323
SLC16A12 solute carrier family 16, member 12 0.239197
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.237401
FUS FUS RNA binding protein 0.237042
MMD monocyte to macrophage differentiation-associated 0.233817
MYOD1 myogenic differentiation 1 0.232029
TTR transthyretin 0.229888
NRBP2 nuclear receptor binding protein 2 0.227752
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.227041
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.222083
NCAN neurocan 0.219617
NOTCH1 notch 1 0.218914
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.218563
SCN3A sodium channel, voltage gated, type III alpha subunit 0.217861
NAV2 neuron navigator 2 0.217511
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.217511
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 0.214017
AANAT aralkylamine N-acetyltransferase 0.213669
GDAP1 ganglioside induced differentiation associated protein 1 0.213322
DPYSL3 dihydropyrimidinase-like 3 0.212627
NOG noggin 0.208825
CA4 carbonic anhydrase IV 0.207451
EGFR epidermal growth factor receptor 0.207451
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.203361
PAX3 paired box 3 0.200999
PLP1 proteolipid protein 1 0.197993
TACR1 tachykinin receptor 1 0.195681
IL6 interleukin 6 0.193719
ITGAD integrin, alpha D 0.191777
ACPP acid phosphatase, prostate 0.190175
CDC37L1 cell division cycle 37-like 1 0.189539
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.187646
SALL3 spalt-like transcription factor 3 0.187333
CRX cone-rod homeobox 0.187333
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.186087
HSPB8 heat shock 22kDa protein 8 0.184853
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.184547
GNS glucosamine (N-acetyl)-6-sulfatase 0.184241
SMN1 survival of motor neuron 1, telomeric 0.184241
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.182723
TSC2 tuberous sclerosis 2 0.182723
PAX7 paired box 7 0.182122
KIF1B kinesin family member 1B 0.181823
FTL ferritin, light polypeptide 0.181524
FTH1 ferritin, heavy polypeptide 1 0.180339
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.180045
PNOC prepronociceptin 0.179459
FGFR4 fibroblast growth factor receptor 4 0.179459
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.176587
MUCL1 mucin-like 1 0.175745
NDNL2 necdin-like 2 0.174911
CA2 carbonic anhydrase II 0.174087
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.173003
NANOG Nanog homeobox 0.172735
OTX1 orthodenticle homeobox 1 0.172201
MKI67 marker of proliferation Ki-67 0.171937
BTG4 B-cell translocation gene 4 0.17141
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.17141
SNCAIP synuclein, alpha interacting protein 0.171149
MAGEH1 melanoma antigen family H1 0.167856
H1F0 H1 histone family, member 0 0.167611
SETX senataxin 0.167125
WNT1 wingless-type MMTV integration site family, member 1 0.167125
RLBP1 retinaldehyde binding protein 1 0.166884
CADM3 cell adhesion molecule 3 0.166884
NT5C1A 5'-nucleotidase, cytosolic IA 0.165932
ASIC3 acid sensing (proton gated) ion channel 3 0.165697
DCTN5 dynactin 5 (p25) 0.165697
SNPH syntaphilin 0.162763
TEF thyrotrophic embryonic factor 0.161905
DBN1 drebrin 1 0.161905
PTPRS protein tyrosine phosphatase, receptor type, S 0.160658
DPYSL2 dihydropyrimidinase-like 2 0.160053
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.160053
TNF tumor necrosis factor 0.159658
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.159074
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.158315
TPPP3 tubulin polymerization-promoting protein family member 3 0.158315
MMP9 matrix metallopeptidase 9 0.156513