neuroma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A nervous system benign neoplasm that is characterized as a nerve tissue tumor. (Human Disease Ontology, DOID_2001)
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Genes

220 genes co-occuring with the disease neuroma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NF2 neurofibromin 2 (merlin) 3.14146
NF1 neurofibromin 1 1.96474
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.86095
CD34 CD34 molecule 1.61754
ENO2 enolase 2 (gamma, neuronal) 1.53436
B3GAT1 beta-1,3-glucuronyltransferase 1 1.33938
GFAP glial fibrillary acidic protein 1.19748
CLDN1 claudin 1 1.15794
CRLF1 cytokine receptor-like factor 1 1.15155
CLDN7 claudin 7 1.14263
NGFR nerve growth factor receptor 1.1072
NCMAP noncompact myelin associated protein 1.07236
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.069
NGF nerve growth factor (beta polypeptide) 1.04209
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.99908
RET ret proto-oncogene 0.965405
MLANA melan-A 0.925039
PEX5L peroxisomal biogenesis factor 5-like 0.898282
TAC1 tachykinin, precursor 1 0.885979
FKBP4 FK506 binding protein 4, 59kDa 0.863046
CALCA calcitonin-related polypeptide alpha 0.86018
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.836837
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.799513
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.796642
CNTF ciliary neurotrophic factor 0.795002
MBP myelin basic protein 0.792131
KRT83 keratin 83, type II 0.782707
RIMS3 regulating synaptic membrane exocytosis 3 0.720461
PCNA proliferating cell nuclear antigen 0.717232
CD68 CD68 molecule 0.706754
ASMTL acetylserotonin O-methyltransferase-like 0.681894
ANO1 anoctamin 1, calcium activated chloride channel 0.673917
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.665563
GDNF glial cell derived neurotrophic factor 0.664769
SOX10 SRY (sex determining region Y)-box 10 0.663975
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.663181
TP53 tumor protein p53 0.66199
GLTSCR1 glioma tumor suppressor candidate region gene 1 0.642221
KRT84 keratin 84, type II 0.639857
ADGRL4 adhesion G protein-coupled receptor L4 0.639463
POU3F1 POU class 3 homeobox 1 0.632777
CRYBB2 crystallin, beta B2 0.631991
ERBB3 erb-b2 receptor tyrosine kinase 3 0.621792
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.621008
COQ6 coenzyme Q6 monooxygenase 0.610838
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.60108
NCOA1 nuclear receptor coactivator 1 0.596402
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.584719
CST7 cystatin F (leukocystatin) 0.581996
CALD1 caldesmon 1 0.574605
FOLH1B folate hydrolase 1B 0.566443
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.566054
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 0.561004
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.553239
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.547807
ERBB2 erb-b2 receptor tyrosine kinase 2 0.545093
NPY neuropeptide Y 0.540055
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.536183
FN1 fibronectin 1 0.533088
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.530768
MB myoglobin 0.529608
CALB2 calbindin 2 0.522659
FNTA farnesyltransferase, CAAX box, alpha 0.521888
HIF3A hypoxia inducible factor 3, alpha subunit 0.51611
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 0.514571
PDE8A phosphodiesterase 8A 0.513417
MITF microphthalmia-associated transcription factor 0.509959
NOTCH1 notch 1 0.490072
NES nestin 0.478289
NRG1 neuregulin 1 0.474498
ARMC10 armadillo repeat containing 10 0.474119
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.473361
CDC42 cell division cycle 42 0.469197
AQP6 aquaporin 6, kidney specific 0.458241
TGFB1 transforming growth factor, beta 1 0.454847
SYP synaptophysin 0.451078
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.43941
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.437906
SCN10A sodium channel, voltage gated, type X alpha subunit 0.434148
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.424389
RICTOR RPTOR independent companion of MTOR, complex 2 0.42139
RAD54B RAD54 homolog B (S. cerevisiae) 0.421016
TYR tyrosinase 0.409787
EZR ezrin 0.40008
BDNF brain-derived neurotrophic factor 0.397843
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.394118
GAP43 growth associated protein 43 0.393001
CTSC cathepsin C 0.387051
DSP desmoplakin 0.384822
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.381852
SNX9 sorting nexin 9 0.377402
ZHX2 zinc fingers and homeoboxes 2 0.375179
MSH4 mutS homolog 4 0.374438
MOCS2 molybdenum cofactor synthesis 2 0.372958
SNN stannin 0.371847
FGF2 fibroblast growth factor 2 (basic) 0.364454
EGFR epidermal growth factor receptor 0.364454
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.360026
PDPN podoplanin 0.356709
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.355235
F8 coagulation factor VIII, procoagulant component 0.353763
NCAM1 neural cell adhesion molecule 1 0.353395
NRG2 neuregulin 2 0.351923
HBA1 hemoglobin, alpha 1 0.348246
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.33651
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.336144
TPM1 tropomyosin 1 (alpha) 0.335412
HBA2 hemoglobin, alpha 2 0.32701
PROS1 protein S (alpha) 0.326646
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.325552
PRNT prion protein (testis specific) 0.317909
FSCN1 fascin actin-bundling protein 1 0.316819
NEFM neurofilament, medium polypeptide 0.313915
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.309566
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.309566
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.309566
CCND1 cyclin D1 0.307757
TNK2 tyrosine kinase, non-receptor, 2 0.306672
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.305948
CASC5 cancer susceptibility candidate 5 0.30342
SIK1 salt-inducible kinase 1 0.300894
PDE9A phosphodiesterase 9A 0.296571
CHL1 cell adhesion molecule L1-like 0.295132
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.292616
IFT122 intraflagellar transport 122 0.287952
PKN1 protein kinase N1 0.287593
NID1 nidogen 1 0.285444
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.284013
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.279724
TP73 tumor protein p73 0.27687
ERBB4 erb-b2 receptor tyrosine kinase 4 0.267977
PTEN phosphatase and tensin homolog 0.26266
SST somatostatin 0.261599
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.260538
PGM1 phosphoglucomutase 1 0.259477
BCAN brevican 0.257358
CAPN1 calpain 1, (mu/I) large subunit 0.252422
S100P S100 calcium binding protein P 0.251718
OLIG2 oligodendrocyte lineage transcription factor 2 0.24996
CD53 CD53 molecule 0.248554
PMEL premelanosome protein 0.246448
BIN2 bridging integrator 2 0.246448
BMP4 bone morphogenetic protein 4 0.242595
FBXO42 F-box protein 42 0.242245
COCH cochlin 0.240847
HAVCR1 hepatitis A virus cellular receptor 1 0.230063
SCGB2A1 secretoglobin, family 2A, member 1 0.227297
SOX6 SRY (sex determining region Y)-box 6 0.224884
ARTN artemin 0.223853
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.223165
OLIG1 oligodendrocyte transcription factor 1 0.216332
SCN3A sodium channel, voltage gated, type III alpha subunit 0.212608
NPS neuropeptide S 0.211597
PAX7 paired box 7 0.211261
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.206248
TUBA1A tubulin, alpha 1a 0.203604
EDA ectodysplasin A 0.192657
PGR progesterone receptor 0.188938
MUTYH mutY homolog 0.186811
NEU2 sialidase 2 (cytosolic sialidase) 0.18472
CD44 CD44 molecule (Indian blood group) 0.183835
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.180937
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.180367
FGF1 fibroblast growth factor 1 (acidic) 0.180367
BMP2 bone morphogenetic protein 2 0.174617
PTPRC protein tyrosine phosphatase, receptor type, C 0.172544
CDKN2A cyclin-dependent kinase inhibitor 2A 0.171036
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.169571
ALLC allantoicase 0.166768
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.165435
PDE10A phosphodiesterase 10A 0.164149
UST uronyl-2-sulfotransferase 0.160948
DAPK1 death-associated protein kinase 1 0.160021
NCAN neurocan 0.15948
CCNH cyclin H 0.1309
EPOR erythropoietin receptor 0.129684
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.129494
DNTT DNA nucleotidylexotransferase 0.126131
LYZ lysozyme 0.116033
CD274 CD274 molecule 0.110933
SSTR3 somatostatin receptor 3 0.109263
AQP2 aquaporin 2 (collecting duct) 0.10912
E2F5 E2F transcription factor 5, p130-binding 0.108944
LATS1 large tumor suppressor kinase 1 0.107602
MDM4 MDM4, p53 regulator 0.105488
NRTN neurturin 0.104522
RPIA ribose 5-phosphate isomerase A 0.103964
COL4A4 collagen, type IV, alpha 4 0.10225
FGA fibrinogen alpha chain 0.102078
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.101871
GSTM3 glutathione S-transferase mu 3 (brain) 0.101215
SSTR1 somatostatin receptor 1 0.101003
RHOB ras homolog family member B 0.100439
SETD1A SET domain containing 1A 0.100015
ALAD aminolevulinate dehydratase 0.099726
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.098678
NMT1 N-myristoyltransferase 1 0.098087
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.097384
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.097347
PRRC2A proline-rich coiled-coil 2A 0.097045
CD79B CD79b molecule, immunoglobulin-associated beta 0.096255
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.095525
PDE4D phosphodiesterase 4D, cAMP-specific 0.094402
AQP3 aquaporin 3 (Gill blood group) 0.093381
WT1 Wilms tumor 1 0.093221
NPPC natriuretic peptide C 0.091738
AQP4 aquaporin 4 0.088478
EDN3 endothelin 3 0.08831
ERCC4 excision repair cross-complementation group 4 0.088268
ATF1 activating transcription factor 1 0.087974
KRT3 keratin 3, type II 0.087508
ANXA5 annexin A5 0.087337
PER3 period circadian clock 3 0.086996
CCNA2 cyclin A2 0.08674
WDFY2 WD repeat and FYVE domain containing 2 0.086697
ERCC5 excision repair cross-complementation group 5 0.086314
CHEK2 checkpoint kinase 2 0.086271
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.086141
FLCN folliculin 0.085319
CHGA chromogranin A 0.085189