neuromuscular junction Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. (Gene Ontology, GO_0031594)
External Link http://amigo.geneontology.org/amigo/term/GO:0031594
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Genes

49 proteins localized to the neuromuscular junction cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APP amyloid beta (A4) precursor protein
CAV3 caveolin 3
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CIB2 calcium and integrin binding family member 2
COL4A5 collagen, type IV, alpha 5
DES desmin
DLG1 discs, large homolog 1 (Drosophila)
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DOK7 docking protein 7
EFNA2 ephrin-A2
EPHA4 EPH receptor A4
EPHA7 EPH receptor A7
F2R coagulation factor II (thrombin) receptor
HDAC4 histone deacetylase 4
ITGA7 integrin, alpha 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
LRP4 low density lipoprotein receptor-related protein 4
MUSK muscle, skeletal, receptor tyrosine kinase
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
NEFM neurofilament, medium polypeptide
NRG1 neuregulin 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDZRN3 PDZ domain containing ring finger 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PSEN1 presenilin 1
PSEN2 presenilin 2
RAPSN receptor-associated protein of the synapse
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SNTA1 syntrophin, alpha 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SV2A synaptic vesicle glycoprotein 2A
SYNC syncoilin, intermediate filament protein
SYNGR1 synaptogyrin 1
SYNGR2 synaptogyrin 2
SYNGR3 synaptogyrin 3
SYNGR4 synaptogyrin 4
TBC1D24 TBC1 domain family, member 24
UNC13A unc-13 homolog A (C. elegans)
UNC13B unc-13 homolog B (C. elegans)
UTRN utrophin