neuromyelitis optica Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A central nervous system disease characterized by acute neuritis located_in eye and demyelination located_in optic nerve and located_in spinal cord. (Human Disease Ontology, DOID_8869)
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Genes

73 genes co-occuring with the disease neuromyelitis optica in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
AQP4 aquaporin 4 4.06329
MOG myelin oligodendrocyte glycoprotein 1.75596
IFNB1 interferon, beta 1, fibroblast 1.2861
MBP myelin basic protein 1.20915
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.01301
HCRT hypocretin (orexin) neuropeptide precursor 0.940364
CNTN2 contactin 2 (axonal) 0.868777
MIP major intrinsic protein of lens fiber 0.806898
LGI1 leucine-rich, glioma inactivated 1 0.771661
PELO pelota homolog (Drosophila) 0.746391
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.745172
NFASC neurofascin 0.698715
GFAP glial fibrillary acidic protein 0.689092
AQP1 aquaporin 1 (Colton blood group) 0.65288
DPYSL5 dihydropyrimidinase-like 5 0.64577
FAM189B family with sequence similarity 189, member B 0.636315
OPN3 opsin 3 0.617877
IL6 interleukin 6 0.608494
IL6R interleukin 6 receptor 0.550911
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.541605
RANGRF RAN guanine nucleotide release factor 0.535796
CIC capicua transcriptional repressor 0.530381
CD19 CD19 molecule 0.501909
JCHAIN joining chain of multimeric IgA and IgM 0.476014
CXCL13 chemokine (C-X-C motif) ligand 13 0.439034
S100B S100 calcium binding protein B 0.426265
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.42589
CCNDBP1 cyclin D-type binding-protein 1 0.420641
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.418394
CD27 CD27 molecule 0.404184
TTK TTK protein kinase 0.397843
NEFH neurofilament, heavy polypeptide 0.389281
ST5 suppression of tumorigenicity 5 0.389281
CD4 CD4 molecule 0.386308
CXCR3 chemokine (C-X-C motif) receptor 3 0.379626
RTN4 reticulon 4 0.369997
CD52 CD52 molecule 0.366301
IL17A interleukin 17A 0.358551
MAG myelin associated glycoprotein 0.357814
GPC5 glypican 5 0.350084
CD180 CD180 molecule 0.348246
MUSK muscle, skeletal, receptor tyrosine kinase 0.344574
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.328834
IL31RA interleukin 31 receptor A 0.325187
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 0.323002
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.316092
RANBP2 RAN binding protein 2 0.315729
RICTOR RPTOR independent companion of MTOR, complex 2 0.31464
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.298731
NPAT nuclear protein, ataxia-telangiectasia locus 0.296931
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.293694
ALB albumin 0.277227
ADSS adenylosuccinate synthase 0.274021
HLA-C major histocompatibility complex, class I, C 0.245396
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.245046
HMGB1 high mobility group box 1 0.23945
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.234225
CCL4 chemokine (C-C motif) ligand 4 0.225917
IFI30 interferon, gamma-inducible protein 30 0.220766
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.21974
GJB6 gap junction protein, beta 6, 30kDa 0.217012
TXNDC9 thioredoxin domain containing 9 0.209918
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 0.209583
GJA1 gap junction protein, alpha 1, 43kDa 0.198064
HSPG2 heparan sulfate proteoglycan 2 0.196779
AQP2 aquaporin 2 (collecting duct) 0.195183
PGAM1 phosphoglycerate mutase 1 (brain) 0.191408
ELANE elastase, neutrophil expressed 0.18621
AVP arginine vasopressin 0.183835
C4A complement component 4A (Rodgers blood group) 0.183541
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.177301
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.170054
CYCS cytochrome c, somatic 0.160574