neuron projection guidance Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues. (Gene Ontology, GO_0097485)
External Link http://amigo.geneontology.org/amigo/term/GO:0097485
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Genes

133 genes participating in the neuron projection guidance biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ANOS1 anosmin 1
ARHGAP35 Rho GTPase activating protein 35
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
BDNF brain-derived neurotrophic factor
BOC BOC cell adhesion associated, oncogene regulated
BSG basigin (Ok blood group)
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CNTN1 contactin 1
CNTN2 contactin 2 (axonal)
CNTN4 contactin 4
CNTN5 contactin 5
CNTN6 contactin 6
CXCL12 chemokine (C-X-C motif) ligand 12
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCC DCC netrin 1 receptor
DPYSL5 dihydropyrimidinase-like 5
DRAXIN dorsal inhibitory axon guidance protein
DSCAM Down syndrome cell adhesion molecule
DSCAML1 Down syndrome cell adhesion molecule like 1
EFNA1 ephrin-A1
EFNA2 ephrin-A2
EFNA3 ephrin-A3
EFNA4 ephrin-A4
EFNA5 ephrin-A5
EFNB1 ephrin-B1
EFNB2 ephrin-B2
EFNB3 ephrin-B3
EMB embigin
ENAH enabled homolog (Drosophila)
EPHA10 EPH receptor A10
EPHA3 EPH receptor A3
EPHA4 EPH receptor A4
EPHA5 EPH receptor A5
EPHA6 EPH receptor A6
EPHA7 EPH receptor A7
EPHA8 EPH receptor A8
EPHB1 EPH receptor B1
EPHB2 EPH receptor B2
EPHB3 EPH receptor B3
EPHB6 EPH receptor B6
EVL Enah/Vasp-like
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FYN FYN proto-oncogene, Src family tyrosine kinase
GLI2 GLI family zinc finger 2
IGSF9 immunoglobulin superfamily, member 9
KALRN kalirin, RhoGEF kinase
KIAA1755 KIAA1755
KIF5A kinesin family member 5A
KIF5B kinesin family member 5B
KIF5C kinesin family member 5C
KIFC2 kinesin family member C2
KLF7 Kruppel-like factor 7 (ubiquitous)
L1CAM L1 cell adhesion molecule
LGI1 leucine-rich, glioma inactivated 1
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LYPLA2 lysophospholipase II
LZTS1 leucine zipper, putative tumor suppressor 1
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYPN myopalladin
NEO1 neogenin 1
NEXN nexilin (F actin binding protein)
NFASC neurofascin
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NPTN neuroplastin
NRCAM neuronal cell adhesion molecule
NRP1 neuropilin 1
NRP2 neuropilin 2
NRXN1 neurexin 1
NRXN3 neurexin 3
NTN3 netrin 3
NTN4 netrin 4
OPHN1 oligophrenin 1
OTX2 orthodenticle homeobox 2
PALLD palladin, cytoskeletal associated protein
PLA2G10 phospholipase A2, group X
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLXNA1 plexin A1
PLXNA3 plexin A3
PLXNA4 plexin A4
POU4F2 POU class 4 homeobox 2
PRKCQ protein kinase C, theta
PTK2 protein tyrosine kinase 2
PTPRH protein tyrosine phosphatase, receptor type, H
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRU protein tyrosine phosphatase, receptor type, U
RELN reelin
RET ret proto-oncogene
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RYK receptor-like tyrosine kinase
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SHH sonic hedgehog
SIAH1 siah E3 ubiquitin protein ligase 1
SLIT2 slit homolog 2 (Drosophila)
SLIT3 slit homolog 3 (Drosophila)
SOS1 son of sevenless homolog 1 (Drosophila)
TNR tenascin R
TRIO trio Rho guanine nucleotide exchange factor
TUBB3 tubulin, beta 3 class III
UNC5C unc-5 homolog C (C. elegans)
UNC5D unc-5 homolog D (C. elegans)
USP33 ubiquitin specific peptidase 33
VASP vasodilator-stimulated phosphoprotein
WNT5A wingless-type MMTV integration site family, member 5A