neuropeptide hormone activity Gene Set
Dataset
GO Molecular Function Annotations 2025
Category
structural or functional annotations
Type
molecular function
Description
The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones. (Gene Ontology , GO_0005184 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0005184
Similar Terms
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Genes
27 genes performing the neuropeptide hormone activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
Symbol
Name
ADCYAP1
adenylate cyclase activating polypeptide 1 (pituitary)
AGRP
agouti related neuropeptide
CALCB
calcitonin-related polypeptide beta
CORT
cortistatin
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CRH
corticotropin releasing hormone
ECRG4
ECRG4 augurin precursor
GALP
galanin-like peptide
GHRH
growth hormone releasing hormone
GPNMB
glycoprotein (transmembrane) nmb
HCRT
hypocretin (orexin) neuropeptide precursor
NLRP3
NLR family, pyrin domain containing 3
NPFF
neuropeptide FF-amide peptide precursor
NPPA
natriuretic peptide A
NPY
neuropeptide Y
OXT
oxytocin/neurophysin I prepropeptide
PARD3
par-3 family cell polarity regulator
PENK
proenkephalin
PNOC
prepronociceptin
PPY
pancreatic polypeptide
PRLH
prolactin releasing hormone
PYY
peptide YY
QRFP
pyroglutamylated RFamide peptide
RIPK2
receptor-interacting serine-threonine kinase 2
SPX
spexin hormone
UCMA
upper zone of growth plate and cartilage matrix associated
UCN
urocortin
