neuropeptide signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor. (Gene Ontology, GO_0007218)
External Link http://amigo.geneontology.org/amigo/term/GO:0007218
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Genes

74 genes participating in the neuropeptide signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGRP agouti related neuropeptide
CCKBR cholecystokinin B receptor
CD200R1 CD200 receptor 1
CMKLR2 chemerin chemokine-like receptor 2
CPE carboxypeptidase E
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
ECEL1 endothelin converting enzyme-like 1
ECRG4 ECRG4 augurin precursor
GALP galanin-like peptide
GALR1 galanin receptor 1
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GLRA1 glycine receptor, alpha 1
GLRA2 glycine receptor, alpha 2
GLRB glycine receptor, beta
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR149 G protein-coupled receptor 149
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR83 G protein-coupled receptor 83
GPR84 G protein-coupled receptor 84
HCRTR1 hypocretin (orexin) receptor 1
KISS1R KISS1 receptor
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
MCHR1 melanin-concentrating hormone receptor 1
MCHR2 melanin-concentrating hormone receptor 2
NMU neuromedin U
NMUR1 neuromedin U receptor 1
NMUR2 neuromedin U receptor 2
NPBWR1 neuropeptides B/W receptor 1
NPBWR2 neuropeptides B/W receptor 2
NPFF neuropeptide FF-amide peptide precursor
NPFFR1 neuropeptide FF receptor 1
NPFFR2 neuropeptide FF receptor 2
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPSR1 neuropeptide S receptor 1
NPVF neuropeptide VF precursor
NPY neuropeptide Y
NTS neurotensin
NTSR1 neurotensin receptor 1 (high affinity)
NTSR2 neurotensin receptor 2
NXPH2 neurexophilin 2
NXPH3 neurexophilin 3
NXPH4 neurexophilin 4
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PDYN prodynorphin
PENK proenkephalin
PNOC prepronociceptin
PPY pancreatic polypeptide
PTGDR2 prostaglandin D2 receptor 2
PYY peptide YY
QRFP pyroglutamylated RFamide peptide
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RXFP3 relaxin/insulin-like family peptide receptor 3
RXFP4 relaxin/insulin-like family peptide receptor 4
SORCS1 sortilin-related VPS10 domain containing receptor 1
SORCS2 sortilin-related VPS10 domain containing receptor 2
SORCS3 sortilin-related VPS10 domain containing receptor 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SORT1 sortilin 1
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SSTR3 somatostatin receptor 3
SSTR4 somatostatin receptor 4
SSTR5 somatostatin receptor 5
UCMA upper zone of growth plate and cartilage matrix associated
UTS2R urotensin 2 receptor