neuroticism Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Disorders in which the symptoms are distressing to the individual and recognized by him or her as being unacceptable. Social relationships may be greatly affected but usually remain within acceptable limits. The disturbance is relatively enduring or recurrent without treatment. (Experimental Factor Ontology, EFO_0004257)
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Genes

25 genes co-occuring with the biological term neuroticism in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APOE apolipoprotein E
BDNF brain-derived neurotrophic factor
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CRHR1 corticotropin releasing hormone receptor 1
DAOA D-amino acid oxidase activator
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
MAOA monoamine oxidase A
MCPH1 microcephalin 1
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
NR3C2 nuclear receptor subfamily 3, group C, member 2
OR1A2 olfactory receptor, family 1, subfamily A, member 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDE4D phosphodiesterase 4D, cAMP-specific
PENK proenkephalin
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
TMPRSS9 transmembrane protease, serine 9
XBP1 X-box binding protein 1