neurotransmitter secretion Gene Set
Dataset
GO Biological Process Annotations 2025
Category
structural or functional annotations
Type
biological process
Description
The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. (Gene Ontology , GO_0007269 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0007269
Similar Terms
Downloads & Tools
The Enrichr link requires JavaScript.
Genes
36 genes participating in the neurotransmitter secretion biological process from the curated GO Biological Process Annotations 2025 dataset.
Symbol
Name
BEST1
bestrophin 1
BRSK1
BR serine/threonine kinase 1
CDK5
cyclin-dependent kinase 5
CPLX1
complexin 1
CPLX2
complexin 2
CPLX3
complexin 3
CPLX4
complexin 4
DNAJC5
DnaJ (Hsp40) homolog, subfamily C, member 5
DVL1
dishevelled segment polarity protein 1
GRM4
glutamate receptor, metabotropic 4
HRH3
histamine receptor H3
LIN7A
lin-7 homolog A (C. elegans)
LIN7B
lin-7 homolog B (C. elegans)
LIN7C
lin-7 homolog C (C. elegans)
NRXN1
neurexin 1
NRXN2
neurexin 2
OTOF
otoferlin
PCLO
piccolo presynaptic cytomatrix protein
PDZD11
PDZ domain containing 11
PIP5K1C
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PTPRN2
protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB3A
RAB3A, member RAS oncogene family
RIMS1
regulating synaptic membrane exocytosis 1
RIMS2
regulating synaptic membrane exocytosis 2
SLC32A1
solute carrier family 32 (GABA vesicular transporter), member 1
SNAP25
synaptosomal-associated protein, 25kDa
SNAPIN
SNAP-associated protein
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
SNPH
syntaphilin
STX1A
syntaxin 1A (brain)
SYN2
synapsin II
SYT1
synaptotagmin I
SYT10
synaptotagmin X
UNC13A
unc-13 homolog A (C. elegans)
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
