neurotrophin signaling pathway Gene Set
Dataset
GO Biological Process Annotations 2025
Category
structural or functional annotations
Type
biological process
Description
A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons. (Gene Ontology , GO_0038179 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0038179
Similar Terms
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Genes
17 genes participating in the neurotrophin signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
Symbol
Name
BCAR1
breast cancer anti-estrogen resistance 1
BDNF
brain-derived neurotrophic factor
CASP3
caspase 3, apoptosis-related cysteine peptidase
DDIT4
DNA-damage-inducible transcript 4
DOCK3
dedicator of cytokinesis 3
HAP1
huntingtin-associated protein 1
KIDINS220
kinase D-interacting substrate, 220kDa
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
NGF
nerve growth factor (beta polypeptide)
NTF3
neurotrophin 3
NTF4
neurotrophin 4
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
RAP1A
RAP1A, member of RAS oncogene family
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
SORT1
sortilin 1
ZFYVE27
zinc finger, FYVE domain containing 27
