neutrophil Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A granulocyte that is the chief phagocytic white blood cell of the blood. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000130)
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Genes

367 genes co-occuring with the biological term neutrophil in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADAM12 ADAM metallopeptidase domain 12
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADD2 adducin 2 (beta)
ADGRE2 adhesion G protein-coupled receptor E2
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADORA3 adenosine A3 receptor
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK2 adenylate kinase 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMBP alpha-1-microglobulin/bikunin precursor
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANXA1 annexin A1
APCS amyloid P component, serum
APOA4 apolipoprotein A-IV
AQP9 aquaporin 9
ARHGAP1 Rho GTPase activating protein 1
ARHGAP32 Rho GTPase activating protein 32
ARHGAP35 Rho GTPase activating protein 35
ARRB1 arrestin, beta 1
AZU1 azurocidin 1
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BPI bactericidal/permeability-increasing protein
BPIFA1 BPI fold containing family A, member 1
BSG basigin (Ok blood group)
BTK Bruton agammaglobulinemia tyrosine kinase
C5 complement component 5
C5AR1 complement component 5a receptor 1
CAMP cathelicidin antimicrobial peptide
CAPN1 calpain 1, (mu/I) large subunit
CAPNS1 calpain, small subunit 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CD177 CD177 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD63 CD63 molecule
CDC42 cell division cycle 42
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK5 cyclin-dependent kinase 5
CDK9 cyclin-dependent kinase 9
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCN3 chloride channel, voltage-sensitive 3
CLU clusterin
CMKLR1 chemerin chemokine-like receptor 1
CNR2 cannabinoid receptor 2 (macrophage)
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CRTC2 CREB regulated transcription coactivator 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSG cathepsin G
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYTH1 cytohesin 1
DCN decorin
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB4A defensin, beta 4A
DGKA diacylglycerol kinase, alpha 80kDa
DGKE diacylglycerol kinase, epsilon 64kDa
DNASE1 deoxyribonuclease I
DRAM1 DNA-damage regulated autophagy modulator 1
EDN1 endothelin 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ELANE elastase, neutrophil expressed
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
F10 coagulation factor X
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASTK Fas-activated serine/threonine kinase
FCAR Fc fragment of IgA receptor
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGA fibrinogen alpha chain
FLOT1 flotillin 1
FLOT2 flotillin 2
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
G6PC3 glucose 6 phosphatase, catalytic, 3
GABARAPL2 GABA(A) receptor-associated protein-like 2
GDF15 growth differentiation factor 15
GFI1 growth factor independent 1 transcription repressor
GLRA2 glycine receptor, alpha 2
GPR132 G protein-coupled receptor 132
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HAX1 HCLS1 associated protein X-1
HCAR2 hydroxycarboxylic acid receptor 2
HCLS1 hematopoietic cell-specific Lyn substrate 1
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
HK3 hexokinase 3 (white cell)
HMGB1 high mobility group box 1
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNB1 interferon, beta 1, fibroblast
IL10 interleukin 10
IL17A interleukin 17A
IL17B interleukin 17B
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
IL6R interleukin 6 receptor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INS insulin
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA9 integrin, alpha 9
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAGN1 jagunal homolog 1 (Drosophila)
JAK2 Janus kinase 2
JAM3 junctional adhesion molecule 3
KDR kinase insert domain receptor
KLF5 Kruppel-like factor 5 (intestinal)
KLK3 kallikrein-related peptidase 3
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LAMP2 lysosomal-associated membrane protein 2
LBR lamin B receptor
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS8 lectin, galactoside-binding, soluble, 8
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRG1 leucine-rich alpha-2-glycoprotein 1
LSP1 lymphocyte-specific protein 1
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP1S microtubule-associated protein 1S
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
MIR146A microRNA 146a
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
N4BP2L2 NEDD4 binding protein 2-like 2
NAMPT nicotinamide phosphoribosyltransferase
NCF1 neutrophil cytosolic factor 1
NCKAP1L NCK-associated protein 1-like
NCR1 natural cytotoxicity triggering receptor 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NKRF NFKB repressing factor
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOX1 NADPH oxidase 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1I2 nuclear receptor subfamily 1, group I, member 2
OCLN occludin
ORM1 orosomucoid 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PADI4 peptidyl arginine deiminase, type IV
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCNA proliferating cell nuclear antigen
PDE9A phosphodiesterase 9A
PECAM1 platelet/endothelial cell adhesion molecule 1
PF4 platelet factor 4
PGLYRP1 peptidoglycan recognition protein 1
PI3 peptidase inhibitor 3, skin-derived
PIGR polymeric immunoglobulin receptor
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCB4 phospholipase C, beta 4
PLD1 phospholipase D1, phosphatidylcholine-specific
PLG plasminogen
PML promyelocytic leukemia
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRAM1 PML-RARA regulated adaptor molecule 1
PRDX6 peroxiredoxin 6
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRTN3 proteinase 3
PSD pleckstrin and Sec7 domain containing
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PTAFR platelet-activating factor receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTX3 pentraxin 3, long
PXN paxillin
RAB27A RAB27A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RADIL Ras association and DIL domains
RAP1A RAP1A, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RARA retinoic acid receptor, alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RHOA ras homolog family member A
RICTOR RPTOR independent companion of MTOR, complex 2
RMDN3 regulator of microtubule dynamics 3
RPS19 ribosomal protein S19
RXRA retinoid X receptor, alpha
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAA1 serum amyloid A1
SDC1 syndecan 1
SDC4 syndecan 4
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPD surfactant protein D
SGK1 serum/glucocorticoid regulated kinase 1
SIGLEC14 sialic acid binding Ig-like lectin 14
SIGLEC5 sialic acid binding Ig-like lectin 5
SIRPA signal-regulatory protein alpha
SIRPB1 signal-regulatory protein beta 1
SLC22A17 solute carrier family 22, member 17
SLPI secretory leukocyte peptidase inhibitor
SNAP23 synaptosomal-associated protein, 23kDa
SOD3 superoxide dismutase 3, extracellular
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPN sialophorin
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
STOM stomatin
SYK spleen tyrosine kinase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TP73 tumor protein p73
TREM1 triggering receptor expressed on myeloid cells 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAV1 vav 1 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VIM vimentin
VNN2 vanin 2
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VWF von Willebrand factor
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase