nfe2l2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description nuclear factor, erythroid 2-like 2|This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 4780)
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Genes

11 genes co-occuring with the biological term nfe2l2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BTG2 BTG family, member 2
CREBBP CREB binding protein
KEAP1 kelch-like ECH-associated protein 1
KMT2D lysine (K)-specific methyltransferase 2D
NFE2L2 nuclear factor, erythroid 2-like 2
NQO1 NAD(P)H dehydrogenase, quinone 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
TP53 tumor protein p53
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)