nfe2l2_15173550_liver_lof_mouse_gpl81_gds514 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS514
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Genes

132 genes differentially expressed following the nfe2l2_15173550_liver_lof_mouse_gpl81_gds514 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
PRM1 protamine 1 0.231234
DTNB dystrobrevin, beta 0.226499
DVL1 dishevelled segment polarity protein 1 0.225065
EMC2 ER membrane protein complex subunit 2 0.219306
DHRSX dehydrogenase/reductase (SDR family) X-linked 0.212861
CYSTM1 cysteine-rich transmembrane module containing 1 0.203711
ZNRF4 zinc and ring finger 4 0.199087
SPRR2F small proline-rich protein 2F 0.198263
DYNLL1 dynein, light chain, LC8-type 1 0.196312
ARMC1 armadillo repeat containing 1 0.190538
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.185964
KLK3 kallikrein-related peptidase 3 0.185858
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.16342
RGS7 regulator of G-protein signaling 7 0.162641
RBKS ribokinase 0.162188
GOLGA4 golgin A4 0.160098
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.153514
SGPP1 sphingosine-1-phosphate phosphatase 1 0.151452
UBAP2L ubiquitin associated protein 2-like 0.149782
SHF Src homology 2 domain containing F 0.12678
PDLIM4 PDZ and LIM domain 4 0.116722
ACHE acetylcholinesterase (Yt blood group) 0.109908
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.097893
HSF2 heat shock transcription factor 2 0.094523
CCDC101 coiled-coil domain containing 101 0.089904
EIF3A eukaryotic translation initiation factor 3, subunit A 0.084732
ADSL adenylosuccinate lyase 0.08117
HIST1H1C histone cluster 1, H1c 0.062943
COL17A1 collagen, type XVII, alpha 1 0.057802
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.050671
ZCCHC7 zinc finger, CCHC domain containing 7 0.050019
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.046391
CLTB clathrin, light chain B 0.040253
CORO2B coronin, actin binding protein, 2B 0.039081
QARS glutaminyl-tRNA synthetase 0.037916
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 0.036953
FLT4 fms-related tyrosine kinase 4 0.036331
ASTN1 astrotactin 1 0.035517
NKX1-2 NK1 homeobox 2 0.033948
WBP4 WW domain binding protein 4 0.029413
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 0.025421
CTSG cathepsin G 0.02309
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 0.02208
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 0.021628
MCM7 minichromosome maintenance complex component 7 0.020677
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.014829
PCID2 PCI domain containing 2 0.0117

decreased expression

Symbol Name Standardized Value
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -1.25512
KLRD1 killer cell lectin-like receptor subfamily D, member 1 -1.23636
CDC25C cell division cycle 25C -1.22672
CCL27 chemokine (C-C motif) ligand 27 -1.18125
PLCD1 phospholipase C, delta 1 -1.18037
GSTM3 glutathione S-transferase mu 3 (brain) -1.17029
AAK1 AP2 associated kinase 1 -1.16044
HFE hemochromatosis -1.08547
INVS inversin -1.08258
GRB10 growth factor receptor-bound protein 10 -1.07722
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -1.03252
ZNFX1 zinc finger, NFX1-type containing 1 -1.02112
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -1.00889
SART3 squamous cell carcinoma antigen recognized by T cells 3 -0.989342
BRD3 bromodomain containing 3 -0.890268
GGPS1 geranylgeranyl diphosphate synthase 1 -0.885249
NDEL1 nudE neurodevelopment protein 1-like 1 -0.883519
DYNLT1 dynein, light chain, Tctex-type 1 -0.85765
CTSC cathepsin C -0.85733
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -0.844403
ANAPC13 anaphase promoting complex subunit 13 -0.834821
GSTM1 glutathione S-transferase mu 1 -0.807108
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -0.791783
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.761097
TFRC transferrin receptor -0.75671
ANK1 ankyrin 1, erythrocytic -0.742742
COMTD1 catechol-O-methyltransferase domain containing 1 -0.741432
SLC25A51 solute carrier family 25, member 51 -0.696384
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -0.676619
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.660238
DOCK9 dedicator of cytokinesis 9 -0.650276
IGLC1 immunoglobulin lambda constant 1 (Mcg marker) -0.646312
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.644491
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.636528
KLK4 kallikrein-related peptidase 4 -0.635675
BIN1 bridging integrator 1 -0.629165
UGP2 UDP-glucose pyrophosphorylase 2 -0.625366
MRPS25 mitochondrial ribosomal protein S25 -0.607317
BIRC3 baculoviral IAP repeat containing 3 -0.597821
EIF4B eukaryotic translation initiation factor 4B -0.572217
TUBGCP4 tubulin, gamma complex associated protein 4 -0.560451
OAT ornithine aminotransferase -0.560285
BANP BTG3 associated nuclear protein -0.551878
CD59 CD59 molecule, complement regulatory protein -0.550301
SELK selenoprotein K -0.547266
ETHE1 ethylmalonic encephalopathy 1 -0.543352
SYCE2 synaptonemal complex central element protein 2 -0.524002
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 -0.507623
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.502472
BMPR1A bone morphogenetic protein receptor, type IA -0.497056
RASAL1 RAS protein activator like 1 (GAP1 like) -0.485763
SURF4 surfeit 4 -0.484593
COL1A2 collagen, type I, alpha 2 -0.478676
CMTR1 cap methyltransferase 1 -0.477524
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -0.471587
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -0.466394
RXRA retinoid X receptor, alpha -0.463265
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit -0.45994
MED12 mediator complex subunit 12 -0.44527
BCL2 B-cell CLL/lymphoma 2 -0.439544
JMJD8 jumonji domain containing 8 -0.439093
UBE2O ubiquitin-conjugating enzyme E2O -0.433978
TYK2 tyrosine kinase 2 -0.429928
ACBD6 acyl-CoA binding domain containing 6 -0.052199
SPATA5 spermatogenesis associated 5 -0.051861
USP22 ubiquitin specific peptidase 22 -0.048709
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) -0.046763
BCAS2 breast carcinoma amplified sequence 2 -0.041193
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.038117
JCHAIN joining chain of multimeric IgA and IgM -0.037579
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit -0.035543
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase -0.031902
PRPF6 pre-mRNA processing factor 6 -0.03177
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.0306
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.026446
KIF1C kinesin family member 1C -0.024348
FMR1 fragile X mental retardation 1 -0.019407
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -0.01863
SYT1 synaptotagmin I -0.013943
CHAF1B chromatin assembly factor 1, subunit B (p60) -0.012083
CDK5 cyclin-dependent kinase 5 -0.008208
NAGLU N-acetylglucosaminidase, alpha -0.007243
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) -0.006939
CRY1 cryptochrome circadian clock 1 -0.00322
RENBP renin binding protein -5.24E-4
Funding