Dataset | GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations |
Category | transcriptomics |
Type | transcription factor perturbation |
Description | transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus) |
External Link | http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS3406 |
Similar Terms | |
Downloads & Tools |
248 genes differentially expressed following the nfe2l2_18059474_liver_lof_mouse_gpl1261_gds3406 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.
Symbol | Name | Standardized Value |
---|---|---|
DPH2 | DPH2 homolog (S. cerevisiae) | 0.214713 |
ZGLP1 | zinc finger, GATA-like protein 1 | 0.213142 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.212481 |
BET1L | Bet1 golgi vesicular membrane trafficking protein-like | 0.212046 |
PRCC | papillary renal cell carcinoma (translocation-associated) | 0.208575 |
GSTA3 | glutathione S-transferase alpha 3 | 0.208546 |
DEPTOR | DEP domain containing MTOR-interacting protein | 0.208489 |
OPRK1 | opioid receptor, kappa 1 | 0.208234 |
CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.207326 |
SORD | sorbitol dehydrogenase | 0.206024 |
STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.20529 |
FAM78B | family with sequence similarity 78, member B | 0.204687 |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.204371 |
HAUS2 | HAUS augmin-like complex, subunit 2 | 0.20374 |
GSTM1 | glutathione S-transferase mu 1 | 0.198999 |
INTS1 | integrator complex subunit 1 | 0.197279 |
BRD3 | bromodomain containing 3 | 0.196297 |
TP53BP1 | tumor protein p53 binding protein 1 | 0.195274 |
EEF2K | eukaryotic elongation factor 2 kinase | 0.194457 |
UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.194234 |
AFG3L1P | AFG3-like AAA ATPase 1, pseudogene | 0.193834 |
HAPLN3 | hyaluronan and proteoglycan link protein 3 | 0.192218 |
NCAM1 | neural cell adhesion molecule 1 | 0.191962 |
DRD2 | dopamine receptor D2 | 0.191452 |
SH3RF1 | SH3 domain containing ring finger 1 | 0.190328 |
RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.190059 |
SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | 0.189566 |
KIF17 | kinesin family member 17 | 0.184557 |
FOXN2 | forkhead box N2 | 0.184145 |
FTH1 | ferritin, heavy polypeptide 1 | 0.180887 |
SRSF3 | serine/arginine-rich splicing factor 3 | 0.180273 |
DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 0.178939 |
LAD1 | ladinin 1 | 0.177317 |
DISP2 | dispatched homolog 2 (Drosophila) | 0.17659 |
TMEM198B | transmembrane protein 198B, pseudogene | 0.175402 |
GSC2 | goosecoid homeobox 2 | 0.174679 |
ADNP2 | ADNP homeobox 2 | 0.17242 |
MLPH | melanophilin | 0.170237 |
ISPD | isoprenoid synthase domain containing | 0.169053 |
CCDC54 | coiled-coil domain containing 54 | 0.164592 |
LOC100507656 | 0.164014 | |
ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.163139 |
VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.162703 |
HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.162392 |
KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.161968 |
PRPS1L1 | phosphoribosyl pyrophosphate synthetase 1-like 1 | 0.155952 |
ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.150414 |
KIAA1045 | KIAA1045 | 0.149845 |
MMP19 | matrix metallopeptidase 19 | 0.149703 |
SNX18 | sorting nexin 18 | 0.147512 |
ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 0.146994 |
RPAP1 | RNA polymerase II associated protein 1 | 0.146884 |
RCAN2 | regulator of calcineurin 2 | 0.145272 |
ZNF704 | zinc finger protein 704 | 0.137519 |
UGT2B7 | UDP glucuronosyltransferase 2 family, polypeptide B7 | 0.134593 |
GSTM2 | glutathione S-transferase mu 2 (muscle) | 0.132063 |
NUPR1L | nuclear protein, transcriptional regulator, 1-like | 0.130493 |
NCAPH | non-SMC condensin I complex, subunit H | 0.127094 |
ACSM2A | acyl-CoA synthetase medium-chain family member 2A | 0.12689 |
PVT1 | Pvt1 oncogene (non-protein coding) | 0.124218 |
PHACTR2 | phosphatase and actin regulator 2 | 0.1235 |
JMJD7 | jumonji domain containing 7 | 0.122251 |
PCDHB14 | protocadherin beta 14 | 0.121395 |
ETV1 | ets variant 1 | 0.119639 |
SLC7A14 | solute carrier family 7, member 14 | 0.118395 |
TSPYL1 | TSPY-like 1 | 0.117604 |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.117233 |
UNCX | UNC homeobox | 0.114526 |
CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.112338 |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.110461 |
UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.108392 |
TSKU | tsukushi, small leucine rich proteoglycan | 0.095315 |
DLGAP2 | discs, large (Drosophila) homolog-associated protein 2 | 0.094822 |
GFM2 | G elongation factor, mitochondrial 2 | 0.093629 |
CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 | 0.089431 |
CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 0.087105 |
SMCO1 | single-pass membrane protein with coiled-coil domains 1 | 0.086166 |
MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.083959 |
AOX1 | aldehyde oxidase 1 | 0.082097 |
PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 | 0.081778 |
PIGR | polymeric immunoglobulin receptor | 0.080693 |
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.073986 |
RBM47 | RNA binding motif protein 47 | 0.072823 |
BHLHA15 | basic helix-loop-helix family, member a15 | 0.070706 |
AACS | acetoacetyl-CoA synthetase | 0.067749 |
UGDH | UDP-glucose 6-dehydrogenase | 0.066023 |
SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 | 0.065745 |
FBXL20 | F-box and leucine-rich repeat protein 20 | 0.06569 |
ANKRD11 | ankyrin repeat domain 11 | 0.065108 |
ZNF638 | zinc finger protein 638 | 0.064707 |
MED14 | mediator complex subunit 14 | 0.062475 |
NOVA2 | neuro-oncological ventral antigen 2 | 0.061817 |
RORC | RAR-related orphan receptor C | 0.051194 |
CAT | catalase | 0.050902 |
ACVR1B | activin A receptor, type IB | 0.050229 |
STXBP1 | syntaxin binding protein 1 | 0.046401 |
CBX5 | chromobox homolog 5 | 0.045366 |
PPARG | peroxisome proliferator-activated receptor gamma | 0.040647 |
ERCC5 | excision repair cross-complementation group 5 | 0.039549 |
JAKMIP2 | janus kinase and microtubule interacting protein 2 | 0.037232 |
TDRD3 | tudor domain containing 3 | 0.036481 |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.03367 |
KREMEN1 | kringle containing transmembrane protein 1 | 0.03323 |
UBE2O | ubiquitin-conjugating enzyme E2O | 0.031814 |
SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) | 0.030429 |
PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.030186 |
MTUS2 | microtubule associated tumor suppressor candidate 2 | 0.029081 |
ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 | 0.026726 |
ARMT1 | acidic residue methyltransferase 1 | 0.023581 |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.023554 |
GRB10 | growth factor receptor-bound protein 10 | 0.021984 |
FEM1A | fem-1 homolog a (C. elegans) | 0.021672 |
HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 | 0.020039 |
PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | 0.019756 |
SNX29 | sorting nexin 29 | 0.019497 |
UGT1A1 | UDP glucuronosyltransferase 1 family, polypeptide A1 | 0.018956 |
UBXN11 | UBX domain protein 11 | 0.016452 |
HNF4G | hepatocyte nuclear factor 4, gamma | 0.015943 |
BBS10 | Bardet-Biedl syndrome 10 | 0.014204 |
IL4R | interleukin 4 receptor | 0.013452 |
VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.013326 |
OR2AG2 | olfactory receptor, family 2, subfamily AG, member 2 | 0.011013 |
RBBP4 | retinoblastoma binding protein 4 | 0.011013 |
AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.010543 |
ZNF266 | zinc finger protein 266 | 0.006805 |
Symbol | Name | Standardized Value |
---|---|---|
TSPAN33 | tetraspanin 33 | -1.23448 |
MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -1.22768 |
SLC16A4 | solute carrier family 16, member 4 | -1.19534 |
PCYT1B | phosphate cytidylyltransferase 1, choline, beta | -1.19289 |
MCM6 | minichromosome maintenance complex component 6 | -1.17425 |
GTF2A1L | general transcription factor IIA, 1-like | -1.1637 |
TTC34 | tetratricopeptide repeat domain 34 | -1.16098 |
RBM45 | RNA binding motif protein 45 | -1.15757 |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -1.1272 |
CRISP1 | cysteine-rich secretory protein 1 | -1.10385 |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -1.08619 |
MARK1 | MAP/microtubule affinity-regulating kinase 1 | -1.07921 |
OSBPL3 | oxysterol binding protein-like 3 | -1.0406 |
PRM1 | protamine 1 | -1.04033 |
ACTRT2 | actin-related protein T2 | -1.03985 |
HOXC5 | homeobox C5 | -1.02695 |
ZCCHC18 | zinc finger, CCHC domain containing 18 | -0.996195 |
WRNIP1 | Werner helicase interacting protein 1 | -0.984616 |
GDI1 | GDP dissociation inhibitor 1 | -0.962694 |
PIAS4 | protein inhibitor of activated STAT, 4 | -0.932905 |
RBM44 | RNA binding motif protein 44 | -0.915585 |
RAD51C | RAD51 paralog C | -0.913786 |
NUDT10 | nudix (nucleoside diphosphate linked moiety X)-type motif 10 | -0.905206 |
LAT2 | linker for activation of T cells family, member 2 | -0.899558 |
IL7R | interleukin 7 receptor | -0.882739 |
FBXW10 | F-box and WD repeat domain containing 10 | -0.861113 |
P2RX3 | purinergic receptor P2X, ligand gated ion channel, 3 | -0.86042 |
CSF2RBP1 | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) pseudogene 1 | -0.81536 |
ICA1L | islet cell autoantigen 1,69kDa-like | -0.765437 |
CPM | carboxypeptidase M | -0.742572 |
LOC646862 | -0.718995 | |
LRP2 | low density lipoprotein receptor-related protein 2 | -0.70468 |
TMEM87A | transmembrane protein 87A | -0.699422 |
BATF2 | basic leucine zipper transcription factor, ATF-like 2 | -0.692204 |
KRTAP19-1 | keratin associated protein 19-1 | -0.670244 |
P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | -0.657314 |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.656115 |
RAMP3 | receptor (G protein-coupled) activity modifying protein 3 | -0.600038 |
KCNQ4 | potassium channel, voltage gated KQT-like subfamily Q, member 4 | -0.597403 |
GLRA1 | glycine receptor, alpha 1 | -0.591779 |
JADE3 | jade family PHD finger 3 | -0.577795 |
ACVR1 | activin A receptor, type I | -0.574611 |
SRPK2 | SRSF protein kinase 2 | -0.564544 |
ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.55862 |
RNF2 | ring finger protein 2 | -0.539237 |
MEIS3 | Meis homeobox 3 | -0.536997 |
CERS6 | ceramide synthase 6 | -0.534724 |
CRHR2 | corticotropin releasing hormone receptor 2 | -0.527298 |
NEUROD4 | neuronal differentiation 4 | -0.506558 |
TBX21 | T-box 21 | -0.498928 |
LY6G6C | lymphocyte antigen 6 complex, locus G6C | -0.485009 |
SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 | -0.472078 |
KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 | -0.469959 |
SPP2 | secreted phosphoprotein 2, 24kDa | -0.467314 |
ELOVL4 | ELOVL fatty acid elongase 4 | -0.462222 |
SLC12A8 | solute carrier family 12, member 8 | -0.461718 |
CXCL17 | chemokine (C-X-C motif) ligand 17 | -0.44886 |
RABIF | RAB interacting factor | -0.448693 |
BCL2A1 | BCL2-related protein A1 | -0.441233 |
TUB | tubby bipartite transcription factor | -0.433785 |
RUNX2 | runt-related transcription factor 2 | -0.429182 |
LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.428173 |
SOX4 | SRY (sex determining region Y)-box 4 | -0.427787 |
PIP5KL1 | phosphatidylinositol-4-phosphate 5-kinase-like 1 | -0.427456 |
FOXE3 | forkhead box E3 | -0.062903 |
ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | -0.062631 |
CELF3 | CUGBP, Elav-like family member 3 | -0.062342 |
PALLD | palladin, cytoskeletal associated protein | -0.061908 |
YIPF4 | Yip1 domain family, member 4 | -0.061114 |
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -0.060452 |
HEATR6 | HEAT repeat containing 6 | -0.060342 |
SLC35E3 | solute carrier family 35, member E3 | -0.059956 |
DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.059676 |
TRIM59 | tripartite motif containing 59 | -0.059563 |
TADA2A | transcriptional adaptor 2A | -0.05691 |
RANBP2 | RAN binding protein 2 | -0.053041 |
IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -0.052277 |
CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.051237 |
HAGHL | hydroxyacylglutathione hydrolase-like | -0.050939 |
S100A10 | S100 calcium binding protein A10 | -0.050839 |
TBC1D13 | TBC1 domain family, member 13 | -0.0507 |
RAB4A | RAB4A, member RAS oncogene family | -0.0507 |
VEZT | vezatin, adherens junctions transmembrane protein | -0.049926 |
AXIN2 | axin 2 | -0.049391 |
MYH14 | myosin, heavy chain 14, non-muscle | -0.048326 |
C2ORF40 | chromosome 2 open reading frame 40 | -0.046754 |
TTR | transthyretin | -0.046693 |
NOX4 | NADPH oxidase 4 | -0.043211 |
SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | -0.042593 |
MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.04199 |
RPP14 | ribonuclease P/MRP 14kDa subunit | -0.040113 |
IVD | isovaleryl-CoA dehydrogenase | -0.036026 |
GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | -0.032847 |
COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | -0.032739 |
NAP1L4 | nucleosome assembly protein 1-like 4 | -0.032305 |
MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.031783 |
HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.030765 |
DYDC2 | DPY30 domain containing 2 | -0.030284 |
BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.030021 |
MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.02825 |
ORC4 | origin recognition complex, subunit 4 | -0.027941 |
LRRC26 | leucine rich repeat containing 26 | -0.025934 |
SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.025912 |
DNM3 | dynamin 3 | -0.025558 |
UBC | ubiquitin C | -0.022955 |
RNF32 | ring finger protein 32 | -0.022014 |
SPATA5L1 | spermatogenesis associated 5-like 1 | -0.020786 |
BPNT1 | 3'(2'), 5'-bisphosphate nucleotidase 1 | -0.018758 |
SEPT10 | septin 10 | -0.018713 |
TM7SF2 | transmembrane 7 superfamily member 2 | -0.017333 |
KRT7 | keratin 7, type II | -0.015884 |
SPATA6 | spermatogenesis associated 6 | -0.015201 |
PDILT | protein disulfide isomerase-like, testis expressed | -0.013767 |
RMDN3 | regulator of microtubule dynamics 3 | -0.012669 |
C11ORF94 | chromosome 11 open reading frame 94 | -0.010633 |
ANKRD17 | ankyrin repeat domain 17 | -0.010356 |
DOLPP1 | dolichyldiphosphatase 1 | -0.009804 |
SGK494 | uncharacterized serine/threonine-protein kinase SgK494 | -0.007224 |
SLC25A42 | solute carrier family 25, member 42 | -0.006647 |
DCT | dopachrome tautomerase | -0.00637 |
HLF | hepatic leukemia factor | -0.004588 |
VPS18 | vacuolar protein sorting 18 homolog (S. cerevisiae) | -0.004218 |
MVD | mevalonate (diphospho) decarboxylase | -0.002059 |