nfe2l2_18059474_liver_lof_mouse_gpl1261_gds3406 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS3406
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Genes

248 genes differentially expressed following the nfe2l2_18059474_liver_lof_mouse_gpl1261_gds3406 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
DPH2 DPH2 homolog (S. cerevisiae) 0.214713
ZGLP1 zinc finger, GATA-like protein 1 0.213142
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.212481
BET1L Bet1 golgi vesicular membrane trafficking protein-like 0.212046
PRCC papillary renal cell carcinoma (translocation-associated) 0.208575
GSTA3 glutathione S-transferase alpha 3 0.208546
DEPTOR DEP domain containing MTOR-interacting protein 0.208489
OPRK1 opioid receptor, kappa 1 0.208234
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.207326
SORD sorbitol dehydrogenase 0.206024
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.20529
FAM78B family with sequence similarity 78, member B 0.204687
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.204371
HAUS2 HAUS augmin-like complex, subunit 2 0.20374
GSTM1 glutathione S-transferase mu 1 0.198999
INTS1 integrator complex subunit 1 0.197279
BRD3 bromodomain containing 3 0.196297
TP53BP1 tumor protein p53 binding protein 1 0.195274
EEF2K eukaryotic elongation factor 2 kinase 0.194457
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.194234
AFG3L1P AFG3-like AAA ATPase 1, pseudogene 0.193834
HAPLN3 hyaluronan and proteoglycan link protein 3 0.192218
NCAM1 neural cell adhesion molecule 1 0.191962
DRD2 dopamine receptor D2 0.191452
SH3RF1 SH3 domain containing ring finger 1 0.190328
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.190059
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 0.189566
KIF17 kinesin family member 17 0.184557
FOXN2 forkhead box N2 0.184145
FTH1 ferritin, heavy polypeptide 1 0.180887
SRSF3 serine/arginine-rich splicing factor 3 0.180273
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.178939
LAD1 ladinin 1 0.177317
DISP2 dispatched homolog 2 (Drosophila) 0.17659
TMEM198B transmembrane protein 198B, pseudogene 0.175402
GSC2 goosecoid homeobox 2 0.174679
ADNP2 ADNP homeobox 2 0.17242
MLPH melanophilin 0.170237
ISPD isoprenoid synthase domain containing 0.169053
CCDC54 coiled-coil domain containing 54 0.164592
LOC100507656 0.164014
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 0.163139
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.162703
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.162392
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.161968
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 0.155952
ANKMY2 ankyrin repeat and MYND domain containing 2 0.150414
KIAA1045 KIAA1045 0.149845
MMP19 matrix metallopeptidase 19 0.149703
SNX18 sorting nexin 18 0.147512
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.146994
RPAP1 RNA polymerase II associated protein 1 0.146884
RCAN2 regulator of calcineurin 2 0.145272
ZNF704 zinc finger protein 704 0.137519
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.134593
GSTM2 glutathione S-transferase mu 2 (muscle) 0.132063
NUPR1L nuclear protein, transcriptional regulator, 1-like 0.130493
NCAPH non-SMC condensin I complex, subunit H 0.127094
ACSM2A acyl-CoA synthetase medium-chain family member 2A 0.12689
PVT1 Pvt1 oncogene (non-protein coding) 0.124218
PHACTR2 phosphatase and actin regulator 2 0.1235
JMJD7 jumonji domain containing 7 0.122251
PCDHB14 protocadherin beta 14 0.121395
ETV1 ets variant 1 0.119639
SLC7A14 solute carrier family 7, member 14 0.118395
TSPYL1 TSPY-like 1 0.117604
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.117233
UNCX UNC homeobox 0.114526
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.112338
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.110461
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.108392
TSKU tsukushi, small leucine rich proteoglycan 0.095315
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.094822
GFM2 G elongation factor, mitochondrial 2 0.093629
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 0.089431
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 0.087105
SMCO1 single-pass membrane protein with coiled-coil domains 1 0.086166
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.083959
AOX1 aldehyde oxidase 1 0.082097
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 0.081778
PIGR polymeric immunoglobulin receptor 0.080693
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.073986
RBM47 RNA binding motif protein 47 0.072823
BHLHA15 basic helix-loop-helix family, member a15 0.070706
AACS acetoacetyl-CoA synthetase 0.067749
UGDH UDP-glucose 6-dehydrogenase 0.066023
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.065745
FBXL20 F-box and leucine-rich repeat protein 20 0.06569
ANKRD11 ankyrin repeat domain 11 0.065108
ZNF638 zinc finger protein 638 0.064707
MED14 mediator complex subunit 14 0.062475
NOVA2 neuro-oncological ventral antigen 2 0.061817
RORC RAR-related orphan receptor C 0.051194
CAT catalase 0.050902
ACVR1B activin A receptor, type IB 0.050229
STXBP1 syntaxin binding protein 1 0.046401
CBX5 chromobox homolog 5 0.045366
PPARG peroxisome proliferator-activated receptor gamma 0.040647
ERCC5 excision repair cross-complementation group 5 0.039549
JAKMIP2 janus kinase and microtubule interacting protein 2 0.037232
TDRD3 tudor domain containing 3 0.036481
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.03367
KREMEN1 kringle containing transmembrane protein 1 0.03323
UBE2O ubiquitin-conjugating enzyme E2O 0.031814
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.030429
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.030186
MTUS2 microtubule associated tumor suppressor candidate 2 0.029081
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 0.026726
ARMT1 acidic residue methyltransferase 1 0.023581
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.023554
GRB10 growth factor receptor-bound protein 10 0.021984
FEM1A fem-1 homolog a (C. elegans) 0.021672
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 0.020039
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.019756
SNX29 sorting nexin 29 0.019497
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.018956
UBXN11 UBX domain protein 11 0.016452
HNF4G hepatocyte nuclear factor 4, gamma 0.015943
BBS10 Bardet-Biedl syndrome 10 0.014204
IL4R interleukin 4 receptor 0.013452
VTCN1 V-set domain containing T cell activation inhibitor 1 0.013326
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 0.011013
RBBP4 retinoblastoma binding protein 4 0.011013
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.010543
ZNF266 zinc finger protein 266 0.006805

decreased expression

Symbol Name Standardized Value
TSPAN33 tetraspanin 33 -1.23448
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -1.22768
SLC16A4 solute carrier family 16, member 4 -1.19534
PCYT1B phosphate cytidylyltransferase 1, choline, beta -1.19289
MCM6 minichromosome maintenance complex component 6 -1.17425
GTF2A1L general transcription factor IIA, 1-like -1.1637
TTC34 tetratricopeptide repeat domain 34 -1.16098
RBM45 RNA binding motif protein 45 -1.15757
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -1.1272
CRISP1 cysteine-rich secretory protein 1 -1.10385
NR4A3 nuclear receptor subfamily 4, group A, member 3 -1.08619
MARK1 MAP/microtubule affinity-regulating kinase 1 -1.07921
OSBPL3 oxysterol binding protein-like 3 -1.0406
PRM1 protamine 1 -1.04033
ACTRT2 actin-related protein T2 -1.03985
HOXC5 homeobox C5 -1.02695
ZCCHC18 zinc finger, CCHC domain containing 18 -0.996195
WRNIP1 Werner helicase interacting protein 1 -0.984616
GDI1 GDP dissociation inhibitor 1 -0.962694
PIAS4 protein inhibitor of activated STAT, 4 -0.932905
RBM44 RNA binding motif protein 44 -0.915585
RAD51C RAD51 paralog C -0.913786
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 -0.905206
LAT2 linker for activation of T cells family, member 2 -0.899558
IL7R interleukin 7 receptor -0.882739
FBXW10 F-box and WD repeat domain containing 10 -0.861113
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -0.86042
CSF2RBP1 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) pseudogene 1 -0.81536
ICA1L islet cell autoantigen 1,69kDa-like -0.765437
CPM carboxypeptidase M -0.742572
LOC646862 -0.718995
LRP2 low density lipoprotein receptor-related protein 2 -0.70468
TMEM87A transmembrane protein 87A -0.699422
BATF2 basic leucine zipper transcription factor, ATF-like 2 -0.692204
KRTAP19-1 keratin associated protein 19-1 -0.670244
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -0.657314
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.656115
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.600038
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 -0.597403
GLRA1 glycine receptor, alpha 1 -0.591779
JADE3 jade family PHD finger 3 -0.577795
ACVR1 activin A receptor, type I -0.574611
SRPK2 SRSF protein kinase 2 -0.564544
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -0.55862
RNF2 ring finger protein 2 -0.539237
MEIS3 Meis homeobox 3 -0.536997
CERS6 ceramide synthase 6 -0.534724
CRHR2 corticotropin releasing hormone receptor 2 -0.527298
NEUROD4 neuronal differentiation 4 -0.506558
TBX21 T-box 21 -0.498928
LY6G6C lymphocyte antigen 6 complex, locus G6C -0.485009
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 -0.472078
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 -0.469959
SPP2 secreted phosphoprotein 2, 24kDa -0.467314
ELOVL4 ELOVL fatty acid elongase 4 -0.462222
SLC12A8 solute carrier family 12, member 8 -0.461718
CXCL17 chemokine (C-X-C motif) ligand 17 -0.44886
RABIF RAB interacting factor -0.448693
BCL2A1 BCL2-related protein A1 -0.441233
TUB tubby bipartite transcription factor -0.433785
RUNX2 runt-related transcription factor 2 -0.429182
LPPR1 lipid phosphate phosphatase-related protein type 1 -0.428173
SOX4 SRY (sex determining region Y)-box 4 -0.427787
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 -0.427456
FOXE3 forkhead box E3 -0.062903
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -0.062631
CELF3 CUGBP, Elav-like family member 3 -0.062342
PALLD palladin, cytoskeletal associated protein -0.061908
YIPF4 Yip1 domain family, member 4 -0.061114
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.060452
HEATR6 HEAT repeat containing 6 -0.060342
SLC35E3 solute carrier family 35, member E3 -0.059956
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.059676
TRIM59 tripartite motif containing 59 -0.059563
TADA2A transcriptional adaptor 2A -0.05691
RANBP2 RAN binding protein 2 -0.053041
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -0.052277
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.051237
HAGHL hydroxyacylglutathione hydrolase-like -0.050939
S100A10 S100 calcium binding protein A10 -0.050839
TBC1D13 TBC1 domain family, member 13 -0.0507
RAB4A RAB4A, member RAS oncogene family -0.0507
VEZT vezatin, adherens junctions transmembrane protein -0.049926
AXIN2 axin 2 -0.049391
MYH14 myosin, heavy chain 14, non-muscle -0.048326
C2ORF40 chromosome 2 open reading frame 40 -0.046754
TTR transthyretin -0.046693
NOX4 NADPH oxidase 4 -0.043211
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 -0.042593
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -0.04199
RPP14 ribonuclease P/MRP 14kDa subunit -0.040113
IVD isovaleryl-CoA dehydrogenase -0.036026
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -0.032847
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor -0.032739
NAP1L4 nucleosome assembly protein 1-like 4 -0.032305
MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 -0.031783
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.030765
DYDC2 DPY30 domain containing 2 -0.030284
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.030021
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.02825
ORC4 origin recognition complex, subunit 4 -0.027941
LRRC26 leucine rich repeat containing 26 -0.025934
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.025912
DNM3 dynamin 3 -0.025558
UBC ubiquitin C -0.022955
RNF32 ring finger protein 32 -0.022014
SPATA5L1 spermatogenesis associated 5-like 1 -0.020786
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 -0.018758
SEPT10 septin 10 -0.018713
TM7SF2 transmembrane 7 superfamily member 2 -0.017333
KRT7 keratin 7, type II -0.015884
SPATA6 spermatogenesis associated 6 -0.015201
PDILT protein disulfide isomerase-like, testis expressed -0.013767
RMDN3 regulator of microtubule dynamics 3 -0.012669
C11ORF94 chromosome 11 open reading frame 94 -0.010633
ANKRD17 ankyrin repeat domain 17 -0.010356
DOLPP1 dolichyldiphosphatase 1 -0.009804
SGK494 uncharacterized serine/threonine-protein kinase SgK494 -0.007224
SLC25A42 solute carrier family 25, member 42 -0.006647
DCT dopachrome tautomerase -0.00637
HLF hepatic leukemia factor -0.004588
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) -0.004218
MVD mevalonate (diphospho) decarboxylase -0.002059