nialamide-3790 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

191 genes differentially expressed following the nialamide-3790 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACACB acetyl-CoA carboxylase beta
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
AGXT alanine-glyoxylate aminotransferase
AKAP13 A kinase (PRKA) anchor protein 13
ALPP alkaline phosphatase, placental
AMH anti-Mullerian hormone
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CABP1 calcium binding protein 1
CCDC121 coiled-coil domain containing 121
CD200 CD200 molecule
CD6 CD6 molecule
CD7 CD7 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CFAP70 cilia and flagella associated protein 70
CHODL chondrolectin
CIB2 calcium and integrin binding family member 2
CNR2 cannabinoid receptor 2 (macrophage)
COLEC10 collectin sub-family member 10 (C-type lectin)
CYBA cytochrome b-245, alpha polypeptide
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DACH1 dachshund family transcription factor 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMC1 DNA meiotic recombinase 1
DNAAF1 dynein, axonemal, assembly factor 1
EFR3B EFR3 homolog B (S. cerevisiae)
EFS embryonal Fyn-associated substrate
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGA fibrinogen alpha chain
FLJ20712 uncharacterized FLJ20712
FRMD8 FERM domain containing 8
FRZB frizzled-related protein
FZD10 frizzled class receptor 10
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GPR85 G protein-coupled receptor 85
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRM1 glutamate receptor, metabotropic 1
HIST1H3E histone cluster 1, H3e
HIST1H3I histone cluster 1, H3i
HLF hepatic leukemia factor
HP haptoglobin
HPS1 Hermansky-Pudlak syndrome 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INA internexin neuronal intermediate filament protein, alpha
IQCC IQ motif containing C
ITSN1 intersectin 1 (SH3 domain protein)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL18 kelch-like family member 18
KLK2 kallikrein-related peptidase 2
LPA lipoprotein, Lp(a)
LRRC31 leucine rich repeat containing 31
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRN2 leucine rich repeat neuronal 2
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MBP myelin basic protein
MEGF6 multiple EGF-like-domains 6
MSI1 musashi RNA-binding protein 1
MST1L macrophage stimulating 1-like
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
MYO7B myosin VIIB
NDN necdin, melanoma antigen (MAGE) family member
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NRIP3 nuclear receptor interacting protein 3
PARP6 poly (ADP-ribose) polymerase family, member 6
PDIA2 protein disulfide isomerase family A, member 2
PDLIM3 PDZ and LIM domain 3
PDLIM4 PDZ and LIM domain 4
PGAP3 post-GPI attachment to proteins 3
PLCL2 phospholipase C-like 2
PRB1 proline-rich protein BstNI subfamily 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PROL1 proline rich, lacrimal 1
RAB30 RAB30, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
SAA3P serum amyloid A3 pseudogene
SCN2A sodium channel, voltage gated, type II alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPHK2 sphingosine kinase 2
SRSF7 serine/arginine-rich splicing factor 7
TBX1 T-box 1
THAP9 THAP domain containing 9
TPSAB1 tryptase alpha/beta 1
TSC22D2 TSC22 domain family, member 2
UBE2I ubiquitin-conjugating enzyme E2I
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WNT16 wingless-type MMTV integration site family, member 16
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)

decreased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
ALPK1 alpha-kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ASB7 ankyrin repeat and SOCS box containing 7
ASPHD1 aspartate beta-hydroxylase domain containing 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF56 chromosome 1 open reading frame 56
C4ORF29 chromosome 4 open reading frame 29
CA11 carbonic anhydrase XI
CBS cystathionine-beta-synthase
CCNK cyclin K
CDON cell adhesion associated, oncogene regulated
CLSTN3 calsyntenin 3
COPZ2 coatomer protein complex, subunit zeta 2
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
CSRNP3 cysteine-serine-rich nuclear protein 3
CYB5R2 cytochrome b5 reductase 2
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DENND2D DENN/MADD domain containing 2D
DUSP2 dual specificity phosphatase 2
EGFL7 EGF-like-domain, multiple 7
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPN1 epsin 1
EREG epiregulin
EXOC6B exocyst complex component 6B
FBXO31 F-box protein 31
FLJ21369 uncharacterized protein FLJ21369
GREB1L growth regulation by estrogen in breast cancer-like
GRTP1 growth hormone regulated TBC protein 1
GSDMD gasdermin D
GTF2I general transcription factor IIi
HDAC7 histone deacetylase 7
HIST1H2BM histone cluster 1, H2bm
HIST1H3G histone cluster 1, H3g
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KRT4 keratin 4, type II
LAMC3 laminin, gamma 3
LIMS2 LIM and senescent cell antigen-like domains 2
LIPG lipase, endothelial
LOC257152 uncharacterized LOC257152
MARK1 MAP/microtubule affinity-regulating kinase 1
MATN3 matrilin 3
MEFV Mediterranean fever
MMP2 matrix metallopeptidase 2
MRPL44 mitochondrial ribosomal protein L44
NME5 NME/NM23 family member 5
NPY1R neuropeptide Y receptor Y1
NSUN6 NOP2/Sun domain family, member 6
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
PRKCE protein kinase C, epsilon
PRPH peripherin
PRSS22 protease, serine, 22
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBMS3 RNA binding motif, single stranded interacting protein 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL1S RFPL1 antisense RNA 1
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPH3A rabphilin 3A
SCIN scinderin
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC16A6 solute carrier family 16, member 6
SLC35F5 solute carrier family 35, member F5
SLMO1 slowmo homolog 1 (Drosophila)
SNHG20 small nucleolar RNA host gene 20
SPTBN2 spectrin, beta, non-erythrocytic 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D30 TBC1 domain family, member 30
THRB thyroid hormone receptor, beta
TRAC T cell receptor alpha constant
TSNAXIP1 translin-associated factor X interacting protein 1
XDH xanthine dehydrogenase
ZBTB22 zinc finger and BTB domain containing 22
ZBTB39 zinc finger and BTB domain containing 39
ZNF155 zinc finger protein 155
ZNF254 zinc finger protein 254
ZNF334 zinc finger protein 334
ZNF37BP zinc finger protein 37B, pseudogene
ZNF446 zinc finger protein 446
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76