nialamide-3871 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the nialamide-3871 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACRV1 acrosomal vesicle protein 1
ACVR1B activin A receptor, type IB
ANGEL2 angel homolog 2 (Drosophila)
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
C14ORF1 chromosome 14 open reading frame 1
C19ORF57 chromosome 19 open reading frame 57
C20ORF195 chromosome 20 open reading frame 195
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CCL13 chemokine (C-C motif) ligand 13
CD79B CD79b molecule, immunoglobulin-associated beta
CDC25C cell division cycle 25C
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CELA3A chymotrypsin-like elastase family, member 3A
CEP295 centrosomal protein 295kDa
CHRD chordin
CNTN1 contactin 1
COL4A2 collagen, type IV, alpha 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DUSP4 dual specificity phosphatase 4
EDA ectodysplasin A
ELOVL5 ELOVL fatty acid elongase 5
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERO1LB ERO1-like beta (S. cerevisiae)
FFAR2 free fatty acid receptor 2
GGT1 gamma-glutamyltransferase 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR182 G protein-coupled receptor 182
GRIK5 glutamate receptor, ionotropic, kainate 5
HIST1H4A histone cluster 1, H4a
HIST1H4E histone cluster 1, H4e
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL11 interleukin 11
IL21 interleukin 21
IRF2 interferon regulatory factor 2
ISL1 ISL LIM homeobox 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
IZUMO4 IZUMO family member 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA1654 KIAA1654 protein
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRT8 keratin 8, type II
KRT83 keratin 83, type II
LOXL3 lysyl oxidase-like 3
LSP1 lymphocyte-specific protein 1
MAOA monoamine oxidase A
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MCTP1 multiple C2 domains, transmembrane 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP11 matrix metallopeptidase 11
MMP13 matrix metallopeptidase 13
MRPL41 mitochondrial ribosomal protein L41
NFIB nuclear factor I/B
NNAT neuronatin
NXF2 nuclear RNA export factor 2
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCM1 pericentriolar material 1
PDLIM5 PDZ and LIM domain 5
PHF2 PHD finger protein 2
PKP2 plakophilin 2
PML promyelocytic leukemia
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PXDC1 PX domain containing 1
RAB40C RAB40C, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RORA RAR-related orphan receptor A
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCAND2P SCAN domain containing 2 pseudogene
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SPPL2B signal peptide peptidase like 2B
SRSF5 serine/arginine-rich splicing factor 5
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYP synaptophysin
TIMP3 TIMP metallopeptidase inhibitor 3
TJAP1 tight junction associated protein 1 (peripheral)
TMPRSS4 transmembrane protease, serine 4
WASL Wiskott-Aldrich syndrome-like
WDFY3 WD repeat and FYVE domain containing 3
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XIST X inactive specific transcript (non-protein coding)
ZNF304 zinc finger protein 304

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALOX15 arachidonate 15-lipoxygenase
BCO1 beta-carotene oxygenase 1
BIRC7 baculoviral IAP repeat containing 7
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
C5AR1 complement component 5a receptor 1
C8ORF44 chromosome 8 open reading frame 44
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC69 coiled-coil domain containing 69
CD3D CD3d molecule, delta (CD3-TCR complex)
CD83 CD83 molecule
CGA glycoprotein hormones, alpha polypeptide
CHRM3 cholinergic receptor, muscarinic 3
CNR2 cannabinoid receptor 2 (macrophage)
CRLF1 cytokine receptor-like factor 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DEPDC5 DEP domain containing 5
DMTN dematin actin binding protein
DUSP8 dual specificity phosphatase 8
ECE1 endothelin converting enzyme 1
EMP3 epithelial membrane protein 3
FAM120C family with sequence similarity 120C
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FLJ22184
FMOD fibromodulin
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR157 G protein-coupled receptor 157
HDAC5 histone deacetylase 5
HOXC4 homeobox C4
HOXC5 homeobox C5
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IGFBP6 insulin-like growth factor binding protein 6
ITM2C integral membrane protein 2C
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLK8 kallikrein-related peptidase 8
KRT15 keratin 15, type I
LIF leukemia inhibitory factor
LRP2 low density lipoprotein receptor-related protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP2 microtubule-associated protein 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MEFV Mediterranean fever
MFGE8 milk fat globule-EGF factor 8 protein
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX3-2 NK3 homeobox 2
NPY5R neuropeptide Y receptor Y5
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PARP16 poly (ADP-ribose) polymerase family, member 16
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX2 paired-like homeodomain 2
PLCD1 phospholipase C, delta 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PPARG peroxisome proliferator-activated receptor gamma
PRSS53 protease, serine, 53
RAB30 RAB30, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF39 ring finger protein 39
RPAP2 RNA polymerase II associated protein 2
SAMHD1 SAM domain and HD domain 1
SECTM1 secreted and transmembrane 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTA1 syntrophin, alpha 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
TESC tescalcin
TFF2 trefoil factor 2
TGFB3 transforming growth factor, beta 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TUBA3C tubulin, alpha 3c
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VIPR1 vasoactive intestinal peptide receptor 1
WFDC2 WAP four-disulfide core domain 2
ZNF137P zinc finger protein 137, pseudogene
ZNF254 zinc finger protein 254
ZNF350 zinc finger protein 350
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446