| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the nicardipine-5397 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AHNAK | AHNAK nucleoprotein |
| ALS2CL | ALS2 C-terminal like |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANGPT4 | angiopoietin 4 |
| APP | amyloid beta (A4) precursor protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATF6B | activating transcription factor 6 beta |
| ATP10D | ATPase, class V, type 10D |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| C16ORF70 | chromosome 16 open reading frame 70 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CD53 | CD53 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CFAP74 | cilia and flagella associated protein 74 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNGB1 | cyclic nucleotide gated channel beta 1 |
| COL11A2 | collagen, type XI, alpha 2 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYTH4 | cytohesin 4 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DRD1 | dopamine receptor D1 |
| DUOX1 | dual oxidase 1 |
| EFNB3 | ephrin-B3 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FLJ11292 | |
| FRMD4B | FERM domain containing 4B |
| FSCN1 | fascin actin-bundling protein 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GK3P | glycerol kinase 3 pseudogene |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRB7 | growth factor receptor-bound protein 7 |
| HFE | hemochromatosis |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HPX | hemopexin |
| IFI6 | interferon, alpha-inducible protein 6 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LOC647070 | uncharacterized LOC647070 |
| LOX | lysyl oxidase |
| MAP1A | microtubule-associated protein 1A |
| MED16 | mediator complex subunit 16 |
| MED31 | mediator complex subunit 31 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MR1 | major histocompatibility complex, class I-related |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NOX1 | NADPH oxidase 1 |
| NPY | neuropeptide Y |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDHB6 | protocadherin beta 6 |
| PEG3 | paternally expressed 3 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PON3 | paraoxonase 3 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRAMEF11 | PRAME family member 11 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RAB6A | RAB6A, member RAS oncogene family |
| RBM34 | RNA binding motif protein 34 |
| RUNX1 | runt-related transcription factor 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SKI | SKI proto-oncogene |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| STK16 | serine/threonine kinase 16 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYT13 | synaptotagmin XIII |
| TBC1D22A | TBC1 domain family, member 22A |
| TBC1D2B | TBC1 domain family, member 2B |
| TMEM40 | transmembrane protein 40 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNP2 | transition protein 2 (during histone to protamine replacement) |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIO | trio Rho guanine nucleotide exchange factor |
| ULBP1 | UL16 binding protein 1 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VPREB3 | pre-B lymphocyte 3 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACP2 | acid phosphatase 2, lysosomal |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTL8 | actin-like 8 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AHR | aryl hydrocarbon receptor |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B9D2 | B9 protein domain 2 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CES3 | carboxylesterase 3 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLSPN | claspin |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRY2 | cryptochrome circadian clock 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DMC1 | DNA meiotic recombinase 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM46C | family with sequence similarity 46, member C |
| FILIP1L | filamin A interacting protein 1-like |
| GAMT | guanidinoacetate N-methyltransferase |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GCA | grancalcin, EF-hand calcium binding protein |
| HOXC5 | homeobox C5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0319L | KIAA0319-like |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MDM4 | MDM4, p53 regulator |
| MFAP2 | microfibrillar-associated protein 2 |
| MGC12488 | |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MYOZ3 | myozenin 3 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NDE1 | nudE neurodevelopment protein 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PDE12 | phosphodiesterase 12 |
| PER3 | period circadian clock 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLXNA3 | plexin A3 |
| POLH | polymerase (DNA directed), eta |
| POM121 | POM121 transmembrane nucleoporin |
| PRR4 | proline rich 4 (lacrimal) |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RFTN1 | raftlin, lipid raft linker 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRPX | sushi-repeat containing protein, X-linked |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| ST5 | suppression of tumorigenicity 5 |
| STBD1 | starch binding domain 1 |
| SYCP2 | synaptonemal complex protein 2 |
| SYNGR3 | synaptogyrin 3 |
| TAOK1 | TAO kinase 1 |
| TCTN2 | tectonic family member 2 |
| TESC | tescalcin |
| TMEM104 | transmembrane protein 104 |
| TMEM180 | transmembrane protein 180 |
| TMEM212 | transmembrane protein 212 |
| TMEM242 | transmembrane protein 242 |
| TMEM39B | transmembrane protein 39B |
| TPK1 | thiamin pyrophosphokinase 1 |
| TTC17 | tetratricopeptide repeat domain 17 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTC33 | tetratricopeptide repeat domain 33 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP36 | ubiquitin specific peptidase 36 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR62 | WD repeat domain 62 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
