| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the nicergoline-5775 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADRA1D | adrenoceptor alpha 1D |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP9A | ATPase, class II, type 9A |
| AVPR1B | arginine vasopressin receptor 1B |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BMP2 | bone morphogenetic protein 2 |
| BMP7 | bone morphogenetic protein 7 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CCDC132 | coiled-coil domain containing 132 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD86 | CD86 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEP41 | centrosomal protein 41kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CTSF | cathepsin F |
| CUX2 | cut-like homeobox 2 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOCK6 | dedicator of cytokinesis 6 |
| DSCAM | Down syndrome cell adhesion molecule |
| EDN3 | endothelin 3 |
| EMC1 | ER membrane protein complex subunit 1 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPN1 | epsin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO2 | F-box protein 2 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| GK | glycerol kinase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR17 | G protein-coupled receptor 17 |
| HFE | hemochromatosis |
| HOOK1 | hook microtubule-tethering protein 1 |
| HRASLS | HRAS-like suppressor |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITGB6 | integrin, beta 6 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA1456 | KIAA1456 |
| KRT38 | keratin 38, type I |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| MDM4 | MDM4, p53 regulator |
| MED25 | mediator complex subunit 25 |
| MFAP3 | microfibrillar-associated protein 3 |
| MMP25 | matrix metallopeptidase 25 |
| MRC2 | mannose receptor, C type 2 |
| MYLIP | myosin regulatory light chain interacting protein |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRCAM | neuronal cell adhesion molecule |
| OGDHL | oxoglutarate dehydrogenase-like |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PLIN2 | perilipin 2 |
| PLK3 | polo-like kinase 3 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| POU2F3 | POU class 2 homeobox 3 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| RBFA | ribosome binding factor A (putative) |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RFPL2 | ret finger protein-like 2 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SRRT | serrate, RNA effector molecule |
| STK11 | serine/threonine kinase 11 |
| STK17A | serine/threonine kinase 17a |
| STON1 | stonin 1 |
| SYT17 | synaptotagmin XVII |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBXA2R | thromboxane A2 receptor |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TXNRD2 | thioredoxin reductase 2 |
| ZNF345 | zinc finger protein 345 |
| ZNF467 | zinc finger protein 467 |
| ZP2 | zona pellucida glycoprotein 2 (sperm receptor) |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| AIM1 | absent in melanoma 1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BICC1 | BicC family RNA binding protein 1 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1R | complement component 1, r subcomponent |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CLDN11 | claudin 11 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLEC2B | C-type lectin domain family 2, member B |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COBL | cordon-bleu WH2 repeat protein |
| COG4 | component of oligomeric golgi complex 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CSF1R | colony stimulating factor 1 receptor |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DENND4A | DENN/MADD domain containing 4A |
| DMTN | dematin actin binding protein |
| EGF | epidermal growth factor |
| EGR2 | early growth response 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FMOD | fibromodulin |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAN | gigaxonin |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HDAC5 | histone deacetylase 5 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOXC4 | homeobox C4 |
| IFI44L | interferon-induced protein 44-like |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIAA0754 | KIAA0754 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LMNB1 | lamin B1 |
| LMO7 | LIM domain 7 |
| LOC257152 | uncharacterized LOC257152 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRK1 | leucine-rich repeat kinase 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NCS1 | neuronal calcium sensor 1 |
| NEK11 | NIMA-related kinase 11 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PC | pyruvate carboxylase |
| PDE12 | phosphodiesterase 12 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PMCH | pro-melanin-concentrating hormone |
| PRMT7 | protein arginine methyltransferase 7 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A3 | S100 calcium binding protein A3 |
| SH2D2A | SH2 domain containing 2A |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TLR2 | toll-like receptor 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM57 | transmembrane protein 57 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF230 | zinc finger protein 230 |
| ZNF41 | zinc finger protein 41 |
| ZNF492 | zinc finger protein 492 |
| ZNF671 | zinc finger protein 671 |
