| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nicergoline-6251 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABHD6 | abhydrolase domain containing 6 |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ANKRD6 | ankyrin repeat domain 6 |
| AQP3 | aquaporin 3 (Gill blood group) |
| BCL2 | B-cell CLL/lymphoma 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACTIN | cactin, spliceosome C complex subunit |
| CALD1 | caldesmon 1 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CAV2 | caveolin 2 |
| CD4 | CD4 molecule |
| CDK12 | cyclin-dependent kinase 12 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP97 | centrosomal protein 97kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CXORF21 | chromosome X open reading frame 21 |
| CYHR1 | cysteine/histidine-rich 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGR1 | early growth response 1 |
| FAM110B | family with sequence similarity 110, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO41 | F-box protein 41 |
| FLJ11292 | |
| FRMD4B | FERM domain containing 4B |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPATCH2L | G patch domain containing 2-like |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H3I | histone cluster 1, H3i |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HMOX1 | heme oxygenase 1 |
| HPX | hemopexin |
| HSPA12A | heat shock 70kDa protein 12A |
| IBSP | integrin-binding sialoprotein |
| INHBA | inhibin, beta A |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| INSIG1 | insulin induced gene 1 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| ITGB5 | integrin, beta 5 |
| JAG1 | jagged 1 |
| JRK | Jrk homolog (mouse) |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 |
| KLF6 | Kruppel-like factor 6 |
| KRT31 | keratin 31, type I |
| LMBR1L | limb development membrane protein 1-like |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LYZ | lysozyme |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP13 | matrix metallopeptidase 13 |
| MMP3 | matrix metallopeptidase 3 |
| MTF2 | metal response element binding transcription factor 2 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MVD | mevalonate (diphospho) decarboxylase |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAG18 | NAG18 mRNA |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDE10A | phosphodiesterase 10A |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLA2G3 | phospholipase A2, group III |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SPPL2B | signal peptide peptidase like 2B |
| SUGP1 | SURP and G patch domain containing 1 |
| TAC3 | tachykinin 3 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TLR2 | toll-like receptor 2 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WSCD1 | WSC domain containing 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| AFG3L2 | AFG3-like AAA ATPase 2 |
| AHR | aryl hydrocarbon receptor |
| APIP | APAF1 interacting protein |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| AXIN1 | axin 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLPP | caseinolytic mitochondrial matrix peptidase proteolytic subunit |
| CORO2A | coronin, actin binding protein, 2A |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CTSC | cathepsin C |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| DOLPP1 | dolichyldiphosphatase 1 |
| EFHD2 | EF-hand domain family, member D2 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM192A | family with sequence similarity 192, member A |
| FANCL | Fanconi anemia, complementation group L |
| FCHO1 | FCH domain only 1 |
| FEM1C | fem-1 homolog c (C. elegans) |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GRAMD4 | GRAM domain containing 4 |
| GRB14 | growth factor receptor-bound protein 14 |
| GTF2I | general transcription factor IIi |
| HCFC2 | host cell factor C2 |
| IMPACT | impact RWD domain protein |
| IPO13 | importin 13 |
| JRKL | JRK-like |
| JUNB | jun B proto-oncogene |
| KIF15 | kinesin family member 15 |
| LAMB1 | laminin, beta 1 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOXL1 | lysyl oxidase-like 1 |
| MCRS1 | microspherule protein 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NBAS | neuroblastoma amplified sequence |
| NCSTN | nicastrin |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NVL | nuclear VCP-like |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PDGFRL | platelet-derived growth factor receptor-like |
| PEX13 | peroxisomal biogenesis factor 13 |
| PGM1 | phosphoglucomutase 1 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PP14571 | uncharacterized LOC100130449 |
| PRPF39 | pre-mRNA processing factor 39 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RANBP17 | RAN binding protein 17 |
| RANGRF | RAN guanine nucleotide release factor |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM41 | RNA binding motif protein 41 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RINT1 | RAD50 interactor 1 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SHPK | sedoheptulokinase |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SP3 | Sp3 transcription factor |
| SPHK1 | sphingosine kinase 1 |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| TCTA | T-cell leukemia translocation altered |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRIM25 | tripartite motif containing 25 |
| TTC17 | tetratricopeptide repeat domain 17 |
| UBXN6 | UBX domain protein 6 |
| URGCP | upregulator of cell proliferation |
| VEGFC | vascular endothelial growth factor C |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR4 | WD repeat domain 4 |
| WLS | wntless Wnt ligand secretion mediator |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF107 | zinc finger protein 107 |
| ZNF143 | zinc finger protein 143 |
| ZNF226 | zinc finger protein 226 |
| ZNF468 | zinc finger protein 468 |
| ZNF668 | zinc finger protein 668 |
| ZNF767P | zinc finger family member 767, pseudogene |
