| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the niclosamide-1498 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AMOTL2 | angiomotin like 2 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BRAP | BRCA1 associated protein |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CARS | cysteinyl-tRNA synthetase |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDHR2 | cadherin-related family member 2 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| ETV5 | ets variant 5 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GPR87 | G protein-coupled receptor 87 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTPBP2 | GTP binding protein 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HBP1 | HMG-box transcription factor 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMOX1 | heme oxygenase 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| KDM4A | lysine (K)-specific demethylase 4A |
| KLF11 | Kruppel-like factor 11 |
| KLF6 | Kruppel-like factor 6 |
| KLF9 | Kruppel-like factor 9 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MNT | MAX network transcriptional repressor |
| MSMO1 | methylsterol monooxygenase 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYO1E | myosin IE |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDH9 | protocadherin 9 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PER1 | period circadian clock 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2G3 | phospholipase A2, group III |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPH | phosphoserine phosphatase |
| RAB9A | RAB9A, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| S100P | S100 calcium binding protein P |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SH3BP2 | SH3-domain binding protein 2 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TES | testin LIM domain protein |
| TMEM209 | transmembrane protein 209 |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF446 | zinc finger protein 446 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| CA2 | carbonic anhydrase II |
| CBR3 | carbonyl reductase 3 |
| CCDC15 | coiled-coil domain containing 15 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CD302 | CD302 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFD | complement factor D (adipsin) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAM155B | family with sequence similarity 155, member B |
| FAM172A | family with sequence similarity 172, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FEN1 | flap structure-specific endonuclease 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GHR | growth hormone receptor |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR19 | G protein-coupled receptor 19 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL22 | interleukin 22 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLHL21 | kelch-like family member 21 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAP9 | microtubule-associated protein 9 |
| MCC | mutated in colorectal cancers |
| METTL16 | methyltransferase like 16 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| ORC1 | origin recognition complex, subunit 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDZD8 | PDZ domain containing 8 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PROCR | protein C receptor, endothelial |
| PRR15L | proline rich 15-like |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RBM12 | RNA binding motif protein 12 |
| RBM14 | RNA binding motif protein 14 |
| RECQL4 | RecQ protein-like 4 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF25 | ring finger protein 25 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SFT2D2 | SFT2 domain containing 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SP1 | Sp1 transcription factor |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCTN2 | tectonic family member 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TPCN1 | two pore segment channel 1 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA4A | tubulin, alpha 4a |
| VGF | VGF nerve growth factor inducible |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| XK | X-linked Kx blood group |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF35 | zinc finger protein 35 |
| ZNF443 | zinc finger protein 443 |
| ZNF562 | zinc finger protein 562 |
