| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the niclosamide-1998 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKRD28 | ankyrin repeat domain 28 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL4A | ADP-ribosylation factor-like 4A |
| BCL2A1 | BCL2-related protein A1 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BTG2 | BTG family, member 2 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD83 | CD83 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC7A | C-type lectin domain family 7, member A |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CTSK | cathepsin K |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DMXL2 | Dmx-like 2 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP2 | dual specificity phosphatase 2 |
| EHD1 | EH-domain containing 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| H2BFS | H2B histone family, member S (pseudogene) |
| HBP1 | HMG-box transcription factor 1 |
| HBS1L | HBS1-like translational GTPase |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H4J | histone cluster 1, H4j |
| HIST2H2BE | histone cluster 2, H2be |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HLA-E | major histocompatibility complex, class I, E |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| ICAM1 | intercellular adhesion molecule 1 |
| IER3 | immediate early response 3 |
| IER5 | immediate early response 5 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IL23A | interleukin 23, alpha subunit p19 |
| JUNB | jun B proto-oncogene |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MTF1 | metal-regulatory transcription factor 1 |
| MZF1 | myeloid zinc finger 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NBN | nibrin |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLAUR | plasminogen activator, urokinase receptor |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| PTX3 | pentraxin 3, long |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS16 | regulator of G-protein signaling 16 |
| RPS11 | ribosomal protein S11 |
| RSF1 | remodeling and spacing factor 1 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDCBP | syndecan binding protein (syntenin) |
| SEC24A | SEC24 family member A |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMIM7 | small integral membrane protein 7 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPON2 | spondin 2, extracellular matrix protein |
| SPP1 | secreted phosphoprotein 1 |
| TANK | TRAF family member-associated NFKB activator |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| WASL | Wiskott-Aldrich syndrome-like |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF335 | zinc finger protein 335 |
| ZNF451 | zinc finger protein 451 |
| Symbol | Name |
|---|---|
| ABHD11 | abhydrolase domain containing 11 |
| ACTL6A | actin-like 6A |
| ADM | adrenomedullin |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BCAP31 | B-cell receptor-associated protein 31 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF48 | |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C6ORF120 | chromosome 6 open reading frame 120 |
| C7ORF49 | chromosome 7 open reading frame 49 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDK4 | cyclin-dependent kinase 4 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFAP20 | cilia and flagella associated protein 20 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COPS7A | COP9 signalosome subunit 7A |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DYNLL1 | dynein, light chain, LC8-type 1 |
| E2F8 | E2F transcription factor 8 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 |
| FAM208B | family with sequence similarity 208, member B |
| FASTKD3 | FAST kinase domains 3 |
| FEN1 | flap structure-specific endonuclease 1 |
| FOXM1 | forkhead box M1 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GFI1 | growth factor independent 1 transcription repressor |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| HEATR3 | HEAT repeat containing 3 |
| HELLS | helicase, lymphoid-specific |
| HIRA | histone cell cycle regulator |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IFITM3 | interferon induced transmembrane protein 3 |
| KIF4A | kinesin family member 4A |
| LBR | lamin B receptor |
| MEIS2 | Meis homeobox 2 |
| MFF | mitochondrial fission factor |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase |
| MRPL28 | mitochondrial ribosomal protein L28 |
| MSRB1 | methionine sulfoxide reductase B1 |
| MTCH2 | mitochondrial carrier 2 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 |
| NAGK | N-acetylglucosamine kinase |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa |
| NDUFC2 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| OAT | ornithine aminotransferase |
| ODC1 | ornithine decarboxylase 1 |
| PANK2 | pantothenate kinase 2 |
| PARP1 | poly (ADP-ribose) polymerase 1 |
| PBK | PDZ binding kinase |
| PCNA | proliferating cell nuclear antigen |
| PEX11B | peroxisomal biogenesis factor 11 beta |
| PFAS | phosphoribosylformylglycinamidine synthase |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PPAN | peter pan homolog (Drosophila) |
| PRDX4 | peroxiredoxin 4 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RAD51AP1 | RAD51 associated protein 1 |
| RANBP6 | RAN binding protein 6 |
| RBM14 | RNA binding motif protein 14 |
| RPA1 | replication protein A1, 70kDa |
| RRM2 | ribonucleotide reductase M2 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| STIL | SCL/TAL1 interrupting locus |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa |
| TFB2M | transcription factor B2, mitochondrial |
| TGDS | TDP-glucose 4,6-dehydratase |
| TM9SF2 | transmembrane 9 superfamily member 2 |
| TMEM168 | transmembrane protein 168 |
| TMEM186 | transmembrane protein 186 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A |
| TSPYL1 | TSPY-like 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| WDR3 | WD repeat domain 3 |
| WRB | tryptophan rich basic protein |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZNF544 | zinc finger protein 544 |
