| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the niclosamide-4018 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| AREG | amphiregulin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATF4 | activating transcription factor 4 |
| AVPR1A | arginine vasopressin receptor 1A |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CBS | cystathionine-beta-synthase |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD58 | CD58 molecule |
| CD6 | CD6 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DCTN1 | dynactin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EML2 | echinoderm microtubule associated protein like 2 |
| FAM129A | family with sequence similarity 129, member A |
| FERMT2 | fermitin family member 2 |
| FGF2 | fibroblast growth factor 2 (basic) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GK | glycerol kinase |
| GK3P | glycerol kinase 3 pseudogene |
| HDAC9 | histone deacetylase 9 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL24 | kelch-like family member 24 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLR | low density lipoprotein receptor |
| LIPG | lipase, endothelial |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MARS | methionyl-tRNA synthetase |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MORC1 | MORC family CW-type zinc finger 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSPH | phosphoserine phosphatase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTX3 | pentraxin 3, long |
| RGS4 | regulator of G-protein signaling 4 |
| RND3 | Rho family GTPase 3 |
| RPL35A | ribosomal protein L35a |
| S100P | S100 calcium binding protein P |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SQSTM1 | sequestosome 1 |
| ST7L | suppression of tumorigenicity 7 like |
| STC2 | stanniocalcin 2 |
| STX3 | syntaxin 3 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THBD | thrombomodulin |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM140 | transmembrane protein 140 |
| TRIB3 | tribbles pseudokinase 3 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| XBP1 | X-box binding protein 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF24 | zinc finger protein 24 |
| ZNF391 | zinc finger protein 391 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALOX12 | arachidonate 12-lipoxygenase |
| APOC4 | apolipoprotein C-IV |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARRB2 | arrestin, beta 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CA9 | carbonic anhydrase IX |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CHMP6 | charged multivesicular body protein 6 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CRMP1 | collapsin response mediator protein 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DBF4B | DBF4 zinc finger B |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNMBP | dynamin binding protein |
| EPN3 | epsin 3 |
| EVPL | envoplakin |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FZD8 | frizzled class receptor 8 |
| GALK1 | galactokinase 1 |
| GBX2 | gastrulation brain homeobox 2 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GPR3 | G protein-coupled receptor 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HAS2 | hyaluronan synthase 2 |
| HDAC7 | histone deacetylase 7 |
| HOXC4 | homeobox C4 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL1R1 | interleukin 1 receptor, type I |
| INHBB | inhibin, beta B |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KLHL3 | kelch-like family member 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMNB1 | lamin B1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC61 | leucine rich repeat containing 61 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MMP9 | matrix metallopeptidase 9 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MTSS1L | metastasis suppressor 1-like |
| MX1 | MX dynamin-like GTPase 1 |
| NDP | Norrie disease (pseudoglioma) |
| NDRG4 | NDRG family member 4 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| ORC1 | origin recognition complex, subunit 1 |
| PALMD | palmdelphin |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PEX6 | peroxisomal biogenesis factor 6 |
| PIP | prolactin-induced protein |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLXNA3 | plexin A3 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPL | periplakin |
| PRR15L | proline rich 15-like |
| PTK6 | protein tyrosine kinase 6 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGCC | regulator of cell cycle |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN1 | Ras and Rab interactor 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SLAMF7 | SLAM family member 7 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSTR4 | somatostatin receptor 4 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SUOX | sulfite oxidase |
| SYT17 | synaptotagmin XVII |
| TGFBR3 | transforming growth factor, beta receptor III |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UGT8 | UDP glycosyltransferase 8 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF215 | zinc finger protein 215 |
| ZNF747 | zinc finger protein 747 |
| ZNF778 | zinc finger protein 778 |
| ZNF85 | zinc finger protein 85 |
