| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the niclosamide-4136 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AMOTL2 | angiomotin like 2 |
| ANXA1 | annexin A1 |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNG2 | cyclin G2 |
| CD52 | CD52 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN1 | claudin 1 |
| CTAGE5 | CTAGE family, member 5 |
| CUL7 | cullin 7 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| ETV5 | ets variant 5 |
| FAM129A | family with sequence similarity 129, member A |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FRMD4B | FERM domain containing 4B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GTPBP2 | GTP binding protein 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H3B | histone cluster 1, H3b |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| JUND | jun D proto-oncogene |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| KLK13 | kallikrein-related peptidase 13 |
| KRT24 | keratin 24, type I |
| LAMC2 | laminin, gamma 2 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLR | low density lipoprotein receptor |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1B | microtubule-associated protein 1B |
| MMP13 | matrix metallopeptidase 13 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NCOR2 | nuclear receptor corepressor 2 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PER1 | period circadian clock 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLK3 | polo-like kinase 3 |
| PLLP | plasmolipin |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPH | phosphoserine phosphatase |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RND1 | Rho family GTPase 1 |
| S100A7 | S100 calcium binding protein A7 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD3 | SMAD family member 3 |
| SMOX | spermine oxidase |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRCAP | Snf2-related CREBBP activator protein |
| TEX14 | testis expressed 14 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TLR2 | toll-like receptor 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| B3GNT1 | |
| BMP4 | bone morphogenetic protein 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CA2 | carbonic anhydrase II |
| CCDC69 | coiled-coil domain containing 69 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CD83 | CD83 molecule |
| CFAP69 | cilia and flagella associated protein 69 |
| CLDND1 | claudin domain containing 1 |
| COCH | cochlin |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DOLK | dolichol kinase |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| EXOSC9 | exosome component 9 |
| FAM69A | family with sequence similarity 69, member A |
| FCHSD2 | FCH and double SH3 domains 2 |
| FEN1 | flap structure-specific endonuclease 1 |
| FHOD1 | formin homology 2 domain containing 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR19 | G protein-coupled receptor 19 |
| HELLS | helicase, lymphoid-specific |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXA4 | homeobox A4 |
| HOXA5 | homeobox A5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRX5 | iroquois homeobox 5 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0125 | KIAA0125 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MCM10 | minichromosome maintenance complex component 10 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MTRF1 | mitochondrial translational release factor 1 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDRG4 | NDRG family member 4 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME5 | NME/NM23 family member 5 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCDHA6 | protocadherin alpha 6 |
| PCDHB8 | protocadherin beta 8 |
| PDE8B | phosphodiesterase 8B |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POPDC3 | popeye domain containing 3 |
| PPIF | peptidylprolyl isomerase F |
| PRR15L | proline rich 15-like |
| RAD51AP1 | RAD51 associated protein 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RLN1 | relaxin 1 |
| RLN2 | relaxin 2 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SCRN3 | secernin 3 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPATA2L | spermatogenesis associated 2-like |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYCP2 | synaptonemal complex protein 2 |
| SYNC | syncoilin, intermediate filament protein |
| TLR5 | toll-like receptor 5 |
| TMEM51 | transmembrane protein 51 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF35 | zinc finger protein 35 |
| ZNF586 | zinc finger protein 586 |
