nicotine dependence Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:0050742
Similar Terms
Downloads & Tools

Genes

542 genes associated with the disease nicotine dependence in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.83769
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 2.79932
HYKK hydroxylysine kinase 2.77122
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.68438
IREB2 iron-responsive element binding protein 2 2.60999
FTO fat mass and obesity associated 2.57086
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 2.45336
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 2.3704
LOC646938 TBC1 domain family, member 2B pseudogene 1.66584
MORF4L1 mortality factor 4 like 1 1.62029
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 1.59661
SH2B1 SH2B adaptor protein 1 1.59558
FLJ45872 1.55738
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.51254
MTCH2 mitochondrial carrier 2 1.45779
RAB4B RAB4B, member RAS oncogene family 1.45253
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 1.45183
EGLN2 egl-9 family hypoxia-inducible factor 2 1.42467
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 1.41288
BDNF brain-derived neurotrophic factor 1.39882
BDNF-AS BDNF antisense RNA 1.36832
SYNPO2 synaptopodin 2 1.36451
ARHGAP10 Rho GTPase activating protein 10 1.3532
UNC79 unc-79 homolog (C. elegans) 1.34859
EVL Enah/Vasp-like 1.33878
DNAH11 dynein, axonemal, heavy chain 11 1.3294
LOC146513 uncharacterized LOC146513 1.31635
KIAA1429 KIAA1429 1.31635
WDR11 WD repeat domain 11 1.31096
SPON1 spondin 1, extracellular matrix protein 1.29991
PKNOX2 PBX/knotted 1 homeobox 2 1.29875
BBX bobby sox homolog (Drosophila) 1.28906
MALRD1 MAM and LDL receptor class A domain containing 1 1.28906
RAB3B RAB3B, member RAS oncogene family 1.28689
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.28289
LINC00158 long intergenic non-protein coding RNA 158 1.27845
AUTS2 autism susceptibility candidate 2 1.27382
C1ORF100 chromosome 1 open reading frame 100 1.26953
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1.26904
CADM1 cell adhesion molecule 1 1.2676
NPHP4 nephronophthisis 4 1.26652
SDK1 sidekick cell adhesion molecule 1 1.26531
LAMA3 laminin, alpha 3 1.25886
CTBP2 C-terminal binding protein 2 1.25596
NRXN1 neurexin 1 1.25477
STK33 serine/threonine kinase 33 1.24687
CLSTN2 calsyntenin 2 1.24623
GRM3 glutamate receptor, metabotropic 3 1.23642
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.23472
RET ret proto-oncogene 1.23034
NELL1 NEL-like 1 (chicken) 1.22658
CA10 carbonic anhydrase X 1.22157
ZHX2 zinc fingers and homeoboxes 2 1.21996
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 1.20823
MYOM1 myomesin 1 1.20388
OR1L6 olfactory receptor, family 1, subfamily L, member 6 1.20337
CASC15 cancer susceptibility candidate 15 (non-protein coding) 1.19386
NRXN3 neurexin 3 1.19386
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 1.19386
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 1.19031
RGS6 regulator of G-protein signaling 6 1.19031
MALT1 MALT1 paracaspase 1.18285
KIAA0040 KIAA0040 1.18117
KRT3 keratin 3, type II 1.17589
SYTL3 synaptotagmin-like 3 1.17489
CELF2 CUGBP, Elav-like family member 2 1.17391
TNRC6A trinucleotide repeat containing 6A 1.17151
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 1.15475
RIC3 RIC3 acetylcholine receptor chaperone 1.15475
ARPP21 cAMP-regulated phosphoprotein, 21kDa 1.15334
COL23A1 collagen, type XXIII, alpha 1 1.14463
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 1.14463
TMEM132D transmembrane protein 132D 1.14463
FAXC failed axon connections homolog (Drosophila) 1.14463
ZNF827 zinc finger protein 827 1.14463
NPC1 Niemann-Pick disease, type C1 1.14463
NALCN sodium leak channel, non selective 1.14341
FSTL1 follistatin-like 1 1.14182
FAIM2 Fas apoptotic inhibitory molecule 2 1.13689
PARD3 par-3 family cell polarity regulator 1.13207
TJP1 tight junction protein 1 1.13087
LARGE like-glycosyltransferase 1.12333
KCNIP1 Kv channel interacting protein 1 1.12191
CNTNAP2 contactin associated protein-like 2 1.12121
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.11614
NEIL2 nei endonuclease VIII-like 2 (E. coli) 1.10764
WDR64 WD repeat domain 64 1.10764
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 1.10487
PARD3B par-3 family cell polarity regulator beta 1.10186
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 1.09895
SGK223 homolog of rat pragma of Rnd2 1.09615
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.08211
SNRPA small nuclear ribonucleoprotein polypeptide A 1.079
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.07599
BHLHE40 basic helix-loop-helix family, member e40 1.07599
FAM186A family with sequence similarity 186, member A 1.07599
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 1.07599
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 1.07599
HEATR1 HEAT repeat containing 1 1.07278
SEC16B SEC16 homolog B (S. cerevisiae) 1.07024
MYH14 myosin, heavy chain 14, non-muscle 1.06913
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1.06431
MYO1E myosin IE 1.06173
NEGR1 neuronal growth regulator 1 1.05943
LINC00479 long intergenic non-protein coding RNA 479 1.05435
NRD1 nardilysin (N-arginine dibasic convertase) 1.0538
RANBP17 RAN binding protein 17 1.04977
ZNF597 zinc finger protein 597 1.04898
MRPS21 mitochondrial ribosomal protein S21 1.04846
SP140L SP140 nuclear body protein-like 1.04846
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.04846
LOC339568 uncharacterized LOC339568 1.04846
CALCR calcitonin receptor 1.04846
NBAS neuroblastoma amplified sequence 1.04717
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.03858
PTPRJ protein tyrosine phosphatase, receptor type, J 1.03718
FAT1 FAT atypical cadherin 1 1.03626
ENDOD1 endonuclease domain containing 1 1.02945
SLC25A48 solute carrier family 25, member 48 1.02476
SYT6 synaptotagmin VI 1.02476
TRPC5 transient receptor potential cation channel, subfamily C, member 5 1.02476
ZNF93 zinc finger protein 93 1.02476
ATXN2L ataxin 2-like 1.02476
CABLES1 Cdk5 and Abl enzyme substrate 1 1.02476
CTNNA3 catenin (cadherin-associated protein), alpha 3 1.02476
CSMD1 CUB and Sushi multiple domains 1 1.02476
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 1.01962
PARP1 poly (ADP-ribose) polymerase 1 1.01962
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.0164
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.00827
MAVS mitochondrial antiviral signaling protein 1.00808
H3F3A H3 histone, family 3A 1.00482
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha 1.00407
ACTN1 actinin, alpha 1 1.00407
GLIS3 GLIS family zinc finger 3 1.00369
ZNF239 zinc finger protein 239 1.00166
ITGA9 integrin, alpha 9 0.99985
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.99967
RERG RAS-like, estrogen-regulated, growth inhibitor 0.99494
CCDC178 coiled-coil domain containing 178 0.9916
TBC1D22A TBC1 domain family, member 22A 0.991255
MSMB microseminoprotein, beta- 0.990056
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3 0.988534
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.987533
ADCY3 adenylate cyclase 3 0.987035
STARD13 StAR-related lipid transfer (START) domain containing 13 0.986376
TUB tubby bipartite transcription factor 0.986376
BIRC5 baculoviral IAP repeat containing 5 0.986376
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 0.984909
AKR1C4 aldo-keto reductase family 1, member C4 0.984909
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.98251
STK32A serine/threonine kinase 32A 0.982036
ULK4 unc-51 like kinase 4 0.981566
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.978787
CNPY1 canopy FGF signaling regulator 1 0.978634
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.975492
IL36RN interleukin 36 receptor antagonist 0.975198
FNDC3B fibronectin type III domain containing 3B 0.971169
SEPT9 septin 9 0.971169
MOV10L1 Mov10 RISC complex RNA helicase like 1 0.971169
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene 0.965779
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.964377
ADGRL3 adhesion G protein-coupled receptor L3 0.963371
CNGA3 cyclic nucleotide gated channel alpha 3 0.962375
CRACR2A calcium release activated channel regulator 2A 0.962251
JPH3 junctophilin 3 0.962004
USP42 ubiquitin specific peptidase 42 0.961144
EPHB1 EPH receptor B1 0.958969
SMOC1 SPARC related modular calcium binding 1 0.958374
WWOX WW domain containing oxidoreductase 0.95603
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.95603
PDE10A phosphodiesterase 10A 0.953745
PLCL1 phospholipase C-like 1 0.952622
CD86 CD86 molecule 0.950418
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 0.950418
SVOPL SVOP-like 0.948266
DCLRE1A DNA cross-link repair 1A 0.945129
NOS1 nitric oxide synthase 1 (neuronal) 0.943097
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.943097
DNM3 dynamin 3 0.943097
CDH13 cadherin 13 0.943097
FSD1L fibronectin type III and SPRY domain containing 1-like 0.940135
LASP1 LIM and SH3 protein 1 0.938237
WIPF3 WAS/WASL interacting protein family, member 3 0.937304
TMPRSS3 transmembrane protease, serine 3 0.93456
TMEM63C transmembrane protein 63C 0.93456
ACPP acid phosphatase, prostate 0.933664
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.930169
POU2F3 POU class 2 homeobox 3 0.928472
FRMPD2 FERM and PDZ domain containing 2 0.928472
RYR3 ryanodine receptor 3 0.926808
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.925987
DOK6 docking protein 6 0.92437
OLFML1 olfactomedin-like 1 0.92437
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.923572
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 0.922781
TTN titin 0.921998
ZCCHC11 zinc finger, CCHC domain containing 11 0.920453
PBX2 pre-B-cell leukemia homeobox 2 0.918934
FHIT fragile histidine triad 0.917442
HPSE2 heparanase 2 (inactive) 0.914528
PGM2L1 phosphoglucomutase 2-like 1 0.912226
DCP1B decapping mRNA 1B 0.912226
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.911472
FYB FYN binding protein 0.910724
FLJ46010 0.909982
ARHGAP44 Rho GTPase activating protein 44 0.908515
MGAM maltase-glucoamylase 0.907073
PCDH15 protocadherin-related 15 0.907073
SSBP3 single stranded DNA binding protein 3 0.905653
SFMBT2 Scm-like with four mbt domains 2 0.903565
KLHL2 kelch-like family member 2 0.902199
C1ORF167 chromosome 1 open reading frame 167 0.897579
NTM neurotrimin 0.894421
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.892579
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 0.892579
MYPN myopalladin 0.891974
MSI2 musashi RNA-binding protein 2 0.890776
TFB2M transcription factor B2, mitochondrial 0.889009
FBXO7 F-box protein 7 0.888428
BTBD11 BTB (POZ) domain containing 11 0.885884
CPT1A carnitine palmitoyltransferase 1A (liver) 0.882152
NBEA neurobeachin 0.881544
JAKMIP1 janus kinase and microtubule interacting protein 1 0.881544
KLHL29 kelch-like family member 29 0.88034
ASTN2 astrotactin 2 0.88034
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.879744
TPO thyroid peroxidase 0.877977
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.877396
TTC39C tetratricopeptide repeat domain 39C 0.877396
EHBP1 EH domain binding protein 1 0.876818
TBC1D2B TBC1 domain family, member 2B 0.876818
XYLT1 xylosyltransferase I 0.876244
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 0.875673
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.875106
NCALD neurocalcin delta 0.874542
NPTXR neuronal pentraxin receptor 0.87287
NRP2 neuropilin 2 0.87287
C11ORF49 chromosome 11 open reading frame 49 0.870688
TOX3 TOX high mobility group box family member 3 0.863933
TM4SF1 transmembrane 4 L six family member 1 0.863933
NPAS3 neuronal PAS domain protein 3 0.861951
PRDM12 PR domain containing 12 0.859982
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.857874
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.854292
LUZP2 leucine zipper protein 2 0.853791
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 0.852303
KCTD16 potassium channel tetramerization domain containing 16 0.851812
AGBL1 ATP/GTP binding protein-like 1 0.849394
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.848443
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.847502
GPC6 glypican 6 0.845188
SUFU suppressor of fused homolog (Drosophila) 0.845188
ATR ATR serine/threonine kinase 0.844732
KIF6 kinesin family member 6 0.841599
SYNPR synaptoporin 0.840288
TBXAS1 thromboxane A synthase 1 (platelet) 0.839855
DOCK8 dedicator of cytokinesis 8 0.839855
NCAM1 neural cell adhesion molecule 1 0.839423
FAM188B family with sequence similarity 188, member B 0.837718
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.836459
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.833585
PEPD peptidase D 0.831981
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.831584
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 0.826025
ZNF850 zinc finger protein 850 0.82519
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 0.824776
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.823134
PRDM1 PR domain containing 1, with ZNF domain 0.823134
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.821519
EFNA5 ephrin-A5 0.821519
PTK2B protein tyrosine kinase 2 beta 0.816063
STK32B serine/threonine kinase 32B 0.814185
TBC1D32 TBC1 domain family, member 32 0.810892
AGXT2 alanine--glyoxylate aminotransferase 2 0.806323
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.803948
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.803614
ALK anaplastic lymphoma receptor tyrosine kinase 0.800979
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.799531
TMEM57 transmembrane protein 57 0.798811
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.798096
FNBP1L formin binding protein 1-like 0.797032
MCPH1 microcephalin 1 0.795979
PCSK5 proprotein convertase subtilisin/kexin type 5 0.79563
GRM8 glutamate receptor, metabotropic 8 0.793562
YAF2 YY1 associated factor 2 0.790203
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.789873
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.785362
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.785047
SIL1 SIL1 nucleotide exchange factor 0.784733
DPF3 D4, zinc and double PHD fingers, family 3 0.784733
RYR2 ryanodine receptor 2 (cardiac) 0.783487
RBM20 RNA binding motif protein 20 0.782256
LRMP lymphoid-restricted membrane protein 0.78195
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.781646
TRIM24 tripartite motif containing 24 0.777184
ARHGAP18 Rho GTPase activating protein 18 0.776893
ENAH enabled homolog (Drosophila) 0.776603
SIRPG signal-regulatory protein gamma 0.776314
SKAP1 src kinase associated phosphoprotein 1 0.774882
PDZRN4 PDZ domain containing ring finger 4 0.773469
REEP1 receptor accessory protein 1 0.772631
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.770976
RNF144A ring finger protein 144A 0.770976
UBA6 ubiquitin-like modifier activating enzyme 6 0.769617
CSNK1G3 casein kinase 1, gamma 3 0.767585
MSRA methionine sulfoxide reductase A 0.766993
GUCA1C guanylate cyclase activator 1C 0.766699
RNF217 ring finger protein 217 0.765529
TRIM9 tripartite motif containing 9 0.763797
GPC5 glypican 5 0.756867
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.756064
IL2RA interleukin 2 receptor, alpha 0.756064
GRB14 growth factor receptor-bound protein 14 0.756064
POSTN periostin, osteoblast specific factor 0.755533
C10ORF107 chromosome 10 open reading frame 107 0.754478
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.754216
TEK TEK tyrosine kinase, endothelial 0.753954
PDE4B phosphodiesterase 4B, cAMP-specific 0.752656
MYRIP myosin VIIA and Rab interacting protein 0.752656
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.750612
RORB RAR-related orphan receptor B 0.749856
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.748856
TMTC4 transmembrane and tetratricopeptide repeat containing 4 0.746884
GAS7 growth arrest-specific 7 0.74664
CLIC5 chloride intracellular channel 5 0.74567
CNGB3 cyclic nucleotide gated channel beta 3 0.74447
CDH23 cadherin-related 23 0.743048
TUBGCP3 tubulin, gamma complex associated protein 3 0.74211
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.740032
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.734299
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.732156
SRFBP1 serum response factor binding protein 1 0.730518
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 0.727087
LOC728755 uncharacterized LOC728755 0.719267
ADAM12 ADAM metallopeptidase domain 12 0.718432
RCAN2 regulator of calcineurin 2 0.718432
SOX5 SRY (sex determining region Y)-box 5 0.716372
DISC1 disrupted in schizophrenia 1 0.715762
GRIK2 glutamate receptor, ionotropic, kainate 2 0.702432
TPST2 tyrosylprotein sulfotransferase 2 0.702075
MED25 mediator complex subunit 25 0.70049
VWA3B von Willebrand factor A domain containing 3B 0.699273
UPP1 uridine phosphorylase 1 0.698413
AK4 adenylate kinase 4 0.698242
FBXL17 F-box and leucine-rich repeat protein 17 0.695541
C20ORF85 chromosome 20 open reading frame 85 0.694711
SCARA3 scavenger receptor class A, member 3 0.693234
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.687839
CCDC109B coiled-coil domain containing 109B 0.684644
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.683305
LEMD2 LEM domain containing 2 0.682129
OR51B5 olfactory receptor, family 51, subfamily B, member 5 0.681256
ATL2 atlastin GTPase 2 0.6784
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 0.677559
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.675487
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.674129
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.673055
OPCML opioid binding protein/cell adhesion molecule-like 0.67173
DGKI diacylglycerol kinase, iota 0.670812
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.669341
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.668836
ZFPM2 zinc finger protein, FOG family member 2 0.665868
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.662072
HK2 hexokinase 2 0.657565
PLBD1 phospholipase B domain containing 1 0.654978
LOC100132735 uncharacterized LOC100132735 0.651654
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) 0.650043
LRRC8C leucine rich repeat containing 8 family, member C 0.648464
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.648464
NEK7 NIMA-related kinase 7 0.646446
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.64588
CRYL1 crystallin, lambda 1 0.64588
FGD5 FYVE, RhoGEF and PH domain containing 5 0.64532
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.644765
AK5 adenylate kinase 5 0.64367
UBASH3B ubiquitin associated and SH3 domain containing B 0.640498
CNTN4 contactin 4 0.639985
FREM1 FRAS1 related extracellular matrix 1 0.639476
GP6 glycoprotein VI (platelet) 0.638472
GRID2 glutamate receptor, ionotropic, delta 2 0.638472
LRRK1 leucine-rich repeat kinase 1 0.637975
CDH10 cadherin 10, type 2 (T2-cadherin) 0.637483
FDX1 ferredoxin 1 0.636031
GLP2R glucagon-like peptide 2 receptor 0.635554
FRRS1L ferric-chelate reductase 1-like 0.634147
DSCAM Down syndrome cell adhesion molecule 0.630132
GLRX3 glutaredoxin 3 0.629714
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.6293
RSAD2 radical S-adenosyl methionine domain containing 2 0.628889
WFDC1 WAP four-disulfide core domain 1 0.628075
RUNX1 runt-related transcription factor 1 0.626482
ARHGAP15 Rho GTPase activating protein 15 0.626482
CHODL chondrolectin 0.625315
GLI3 GLI family zinc finger 3 0.62455
IMMT inner membrane protein, mitochondrial 0.622315
ST18 suppression of tumorigenicity 18, zinc finger 0.61912
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.617756
SMYD5 SMYD family member 5 0.61742
CDCA7L cell division cycle associated 7-like 0.613722
COL4A1 collagen, type IV, alpha 1 0.611353
ACAN aggrecan 0.610366
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.610041
BICC1 BicC family RNA binding protein 1 0.607498
ZNF385D zinc finger protein 385D 0.606572
PRKG1 protein kinase, cGMP-dependent, type I 0.604465
CTNND2 catenin (cadherin-associated protein), delta 2 0.60417
OR8D1 olfactory receptor, family 8, subfamily D, member 1 0.603877
TCERG1L transcription elongation regulator 1-like 0.601861
GRID1 glutamate receptor, ionotropic, delta 1 0.601579
CADPS Ca++-dependent secretion activator 0.601298
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.600187
UST uronyl-2-sulfotransferase 0.598248
CARD6 caspase recruitment domain family, member 6 0.597668
PDE4D phosphodiesterase 4D, cAMP-specific 0.595401
ARL8A ADP-ribosylation factor-like 8A 0.594847
GRM6 glutamate receptor, metabotropic 6 0.593482
DLG2 discs, large homolog 2 (Drosophila) 0.592677
PLB1 phospholipase B1 0.592146
GCA grancalcin, EF-hand calcium binding protein 0.585627
COL13A1 collagen, type XIII, alpha 1 0.584916
ERBB4 erb-b2 receptor tyrosine kinase 4 0.584916
GRIP2 glutamate receptor interacting protein 2 0.584448
PRKCB protein kinase C, beta 0.583062
RPH3AL rabphilin 3A-like (without C2 domains) 0.582607
SGSM1 small G protein signaling modulator 1 0.581481
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.58124
UNC13C unc-13 homolog C (C. elegans) 0.580521
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.580283
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.578411
PTGES prostaglandin E synthase 0.576591
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.575259
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 0.574169
SIRPD signal-regulatory protein delta 0.57331
ELF5 E74-like factor 5 (ets domain transcription factor) 0.572462
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.572462
FRMD4A FERM domain containing 4A 0.571834
GRM7 glutamate receptor, metabotropic 7 0.571005
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 0.569379
KDM4C lysine (K)-specific demethylase 4C 0.568383
PLD5 phospholipase D family, member 5 0.568383
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.567403
ZBTB16 zinc finger and BTB domain containing 16 0.567015
RPTOR regulatory associated protein of MTOR, complex 1 0.566055
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.565297
CXADR coxsackie virus and adenovirus receptor 0.564548
PARK2 parkin RBR E3 ubiquitin protein ligase 0.564548
ATG7 autophagy related 7 0.563624
ASIC2 acid sensing (proton gated) ion channel 2 0.563434
CCBE1 collagen and calcium binding EGF domains 1 0.563434
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.562845
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 0.55923
CHN2 chimerin 2 0.555799
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.555623
PRRC2A proline-rich coiled-coil 2A 0.55372
PRUNE2 prune homolog 2 (Drosophila) 0.552872
CHD7 chromodomain helicase DNA binding protein 7 0.552704
SMYD3 SET and MYND domain containing 3 0.552536
BCL9 B-cell CLL/lymphoma 9 0.552202
BAG6 BCL2-associated athanogene 6 0.552035
PTPRD protein tyrosine phosphatase, receptor type, D 0.552035
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.551538
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.547071
PTPRB protein tyrosine phosphatase, receptor type, B 0.546763
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.546152
ARMC4 armadillo repeat containing 4 0.545848
PBX1 pre-B-cell leukemia homeobox 1 0.545848
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.545245
ADGRF5 adhesion G protein-coupled receptor F5 0.54368
FRMD4B FERM domain containing 4B 0.542899
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.542281
PDGFRL platelet-derived growth factor receptor-like 0.540011
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.539863
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.538831
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.538831
GRIK4 glutamate receptor, ionotropic, kainate 4 0.538685
MYOM2 myomesin 2 0.537098
LHFPL3 lipoma HMGIC fusion partner-like 3 0.535547
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.53513
LRP1B low density lipoprotein receptor-related protein 1B 0.53403
CNTN6 contactin 6 0.533894
FGF1 fibroblast growth factor 1 (acidic) 0.532414
PRKCH protein kinase C, eta 0.53162
ANGPT2 angiopoietin 2 0.531096
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.530835
ATRNL1 attractin-like 1 0.530188
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.529293
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.528535
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.527043
GMDS GDP-mannose 4,6-dehydratase 0.526189
TTLL11 tubulin tyrosine ligase-like family member 11 0.525826
DCLK1 doublecortin-like kinase 1 0.525343
ADGRL2 adhesion G protein-coupled receptor L2 0.524864
ZBTB44 zinc finger and BTB domain containing 44 0.523681
SLC12A8 solute carrier family 12, member 8 0.523447
GDAP1 ganglioside induced differentiation associated protein 1 0.522288
PRKCE protein kinase C, epsilon 0.52115
ZHX3 zinc fingers and homeoboxes 3 0.520925
ABAT 4-aminobutyrate aminotransferase 0.520925
ATG14 autophagy related 14 0.520588
OSBPL1A oxysterol binding protein-like 1A 0.520364
IMPACT impact RWD domain protein 0.520364
XKR4 XK, Kell blood group complex subunit-related family, member 4 0.519478
GRM5 glutamate receptor, metabotropic 5 0.519368
MAST2 microtubule associated serine/threonine kinase 2 0.519149
ESRRG estrogen-related receptor gamma 0.519039
LPP LIM domain containing preferred translocation partner in lipoma 0.518712
LINGO2 leucine rich repeat and Ig domain containing 2 0.516256
RELN reelin 0.515734
TENM4 teneurin transmembrane protein 4 0.514805
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.514805
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.514703
PBRM1 polybromo 1 0.513889
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.512193
SLC45A2 solute carrier family 45, member 2 0.5118
ZNF292 zinc finger protein 292 0.511215
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.510252
RIMBP2 RIMS binding protein 2 0.509776
KIF11 kinesin family member 11 0.50874
NLRP5 NLR family, pyrin domain containing 5 0.508554
CEP120 centrosomal protein 120kDa 0.506603
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.506176
PID1 phosphotyrosine interaction domain containing 1 0.505403
MAP1A microtubule-associated protein 1A 0.504504
RBMS3 RNA binding motif, single stranded interacting protein 3 0.503687
SDK2 sidekick cell adhesion molecule 2 0.50275
PCNXL2 pecanex-like 2 (Drosophila) 0.502683
RAP1GAP2 RAP1 GTPase activating protein 2 0.502617
VWC2 von Willebrand factor C domain containing 2 0.502617
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.500925
NINJ2 ninjurin 2 0.500733
COL15A1 collagen, type XV, alpha 1 0.499847
LTBP1 latent transforming growth factor beta binding protein 1 0.498914
SAMD4A sterile alpha motif domain containing 4A 0.498668
TOX thymocyte selection-associated high mobility group box 0.497636
COL26A1 collagen, type XXVI, alpha 1 0.497516
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.497396
EPHB2 EPH receptor B2 0.497276
CREB5 cAMP responsive element binding protein 5 0.497098
SYNE2 spectrin repeat containing, nuclear envelope 2 0.497098
CCDC129 coiled-coil domain containing 129 0.496979
TENM2 teneurin transmembrane protein 2 0.496919