nicotinic acid-3043 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the nicotinic acid-3043 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACHE acetylcholinesterase (Yt blood group)
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGRL2 adhesion G protein-coupled receptor L2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMACR alpha-methylacyl-CoA racemase
ANGEL2 angel homolog 2 (Drosophila)
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BMP7 bone morphogenetic protein 7
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF12 chromosome 10 open reading frame 12
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN2 calpain 2, (m/II) large subunit
CD59 CD59 molecule, complement regulatory protein
CD80 CD80 molecule
CEMP1 cementum protein 1
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLDN17 claudin 17
CLGN calmegin
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRAT carnitine O-acetyltransferase
CRHR2 corticotropin releasing hormone receptor 2
CRTAC1 cartilage acidic protein 1
CXCL13 chemokine (C-X-C motif) ligand 13
CYB561 cytochrome b561
DDO D-aspartate oxidase
DLK2 delta-like 2 homolog (Drosophila)
DOCK6 dedicator of cytokinesis 6
DSCAM Down syndrome cell adhesion molecule
DSCR4 Down syndrome critical region 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP4 dual specificity phosphatase 4
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EMP1 epithelial membrane protein 1
EPHA5 EPH receptor A5
ESR2 estrogen receptor 2 (ER beta)
FASLG Fas ligand (TNF superfamily, member 6)
GABARAPL1 GABA(A) receptor-associated protein like 1
GAS2L1 growth arrest-specific 2 like 1
GCKR glucokinase (hexokinase 4) regulator
GHRH growth hormone releasing hormone
GJB4 gap junction protein, beta 4, 30.3kDa
GPR20 G protein-coupled receptor 20
GPR35 G protein-coupled receptor 35
GRAMD3 GRAM domain containing 3
GRIK2 glutamate receptor, ionotropic, kainate 2
GSTT1 glutathione S-transferase theta 1
HIST1H2BC histone cluster 1, H2bc
HLA-DRA major histocompatibility complex, class II, DR alpha
HOXA11 homeobox A11
HOXA4 homeobox A4
HPSE2 heparanase 2 (inactive)
ICOSLG inducible T-cell co-stimulator ligand
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNIP1 Kv channel interacting protein 1
KCTD17 potassium channel tetramerization domain containing 17
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRC41 leucine rich repeat containing 41
MBP myelin basic protein
MECOM MDS1 and EVI1 complex locus
MPDZ multiple PDZ domain protein
MVD mevalonate (diphospho) decarboxylase
MYH14 myosin, heavy chain 14, non-muscle
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYOZ3 myozenin 3
NPEPL1 aminopeptidase-like 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCP4 Purkinje cell protein 4
PDE11A phosphodiesterase 11A
PDGFB platelet-derived growth factor beta polypeptide
PKP1 plakophilin 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRELP proline/arginine-rich end leucine-rich repeat protein
PRICKLE3 prickle homolog 3 (Drosophila)
PRKCZ protein kinase C, zeta
PTGIS prostaglandin I2 (prostacyclin) synthase
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RIMS2 regulating synaptic membrane exocytosis 2
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SCAND2P SCAN domain containing 2 pseudogene
SEC14L5 SEC14-like 5 (S. cerevisiae)
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SMG7-AS1 SMG7 antisense RNA 1
SOD2 superoxide dismutase 2, mitochondrial
SPRR2C small proline-rich protein 2C (pseudogene)
SRPX2 sushi-repeat containing protein, X-linked 2
SUGP1 SURP and G patch domain containing 1
SULT4A1 sulfotransferase family 4A, member 1
TIMELESS timeless circadian clock
TMOD1 tropomodulin 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TSHR thyroid stimulating hormone receptor
TUBA4B tubulin, alpha 4b
ZFHX2 zinc finger homeobox 2

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGB androglobin
AGO3 argonaute RISC catalytic component 3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIM2 absent in melanoma 2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ASB7 ankyrin repeat and SOCS box containing 7
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CASP5 caspase 5, apoptosis-related cysteine peptidase
CD9 CD9 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEP97 centrosomal protein 97kDa
CFAP69 cilia and flagella associated protein 69
CFP complement factor properdin
CHMP6 charged multivesicular body protein 6
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
EDAR ectodysplasin A receptor
FAM102A family with sequence similarity 102, member A
FAM120C family with sequence similarity 120C
FAM63A family with sequence similarity 63, member A
FKBPL FK506 binding protein like
FLT4 fms-related tyrosine kinase 4
FPGS folylpolyglutamate synthase
GDAP1 ganglioside induced differentiation associated protein 1
GNL1 guanine nucleotide binding protein-like 1
GPR27 G protein-coupled receptor 27
GUCA2A guanylate cyclase activator 2A (guanylin)
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HOXB9 homeobox B9
IBSP integrin-binding sialoprotein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0753 KIAA0753
KIF3B kinesin family member 3B
KLHL12 kelch-like family member 12
LAX1 lymphocyte transmembrane adaptor 1
LOC100287590 uncharacterized LOC100287590
LOXL3 lysyl oxidase-like 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MCPH1 microcephalin 1
MRAS muscle RAS oncogene homolog
MREG melanoregulin
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX2 MX dynamin-like GTPase 2
MYO15A myosin XVA
NEK11 NIMA-related kinase 11
NT5DC3 5'-nucleotidase domain containing 3
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PBOV1 prostate and breast cancer overexpressed 1
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIPOX pipecolic acid oxidase
PLA2G1B phospholipase A2, group IB (pancreas)
PLAT plasminogen activator, tissue
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRB3 proline-rich protein BstNI subfamily 3
PTDSS2 phosphatidylserine synthase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABL6 RAB, member RAS oncogene family-like 6
RAP1GAP2 RAP1 GTPase activating protein 2
RNF31 ring finger protein 31
RPL23AP53 ribosomal protein L23a pseudogene 53
SAV1 salvador family WW domain containing protein 1
SIPA1 signal-induced proliferation-associated 1
SIX3 SIX homeobox 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC16A6 solute carrier family 16, member 6
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPATA2L spermatogenesis associated 2-like
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TBC1D17 TBC1 domain family, member 17
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMC5 transmembrane channel-like 5
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
TTC26 tetratricopeptide repeat domain 26
UBQLN4 ubiquilin 4
ZNF225 zinc finger protein 225
ZNF484 zinc finger protein 484
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76