Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the nicotinic acid-3381 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
ACAN | aggrecan |
ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
ANGPTL2 | angiopoietin-like 2 |
APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
ARC | activity-regulated cytoskeleton-associated protein |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
ATG10 | autophagy related 10 |
BTF3P11 | basic transcription factor 3 pseudogene 11 |
C18ORF25 | chromosome 18 open reading frame 25 |
CASP2 | caspase 2, apoptosis-related cysteine peptidase |
CCRL2 | chemokine (C-C motif) receptor-like 2 |
CD47 | CD47 molecule |
CD6 | CD6 molecule |
CDC42 | cell division cycle 42 |
CDO1 | cysteine dioxygenase type 1 |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CEP41 | centrosomal protein 41kDa |
CERS4 | ceramide synthase 4 |
CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
CTNS | cystinosin, lysosomal cystine transporter |
CYLD | cylindromatosis (turban tumor syndrome) |
DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
DGCR8 | DGCR8 microprocessor complex subunit |
DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
ELP6 | elongator acetyltransferase complex subunit 6 |
EMID1 | EMI domain containing 1 |
ERCC2 | excision repair cross-complementation group 2 |
FAXDC2 | fatty acid hydroxylase domain containing 2 |
FBLN1 | fibulin 1 |
FCAR | Fc fragment of IgA receptor |
FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
FGF5 | fibroblast growth factor 5 |
FOXG1 | forkhead box G1 |
FRMD1 | FERM domain containing 1 |
FRMD8 | FERM domain containing 8 |
GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
GK2 | glycerol kinase 2 |
GM2A | GM2 ganglioside activator |
GPR176 | G protein-coupled receptor 176 |
GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
HCG4 | HLA complex group 4 (non-protein coding) |
HIST1H2BM | histone cluster 1, H2bm |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HLF | hepatic leukemia factor |
HR | hair growth associated |
IGF2-AS | IGF2 antisense RNA |
IGLJ3 | immunoglobulin lambda joining 3 |
IL18 | interleukin 18 |
ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
KXD1 | KxDL motif containing 1 |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
LMNA | lamin A/C |
MAP1A | microtubule-associated protein 1A |
MAPK7 | mitogen-activated protein kinase 7 |
MET | MET proto-oncogene, receptor tyrosine kinase |
MFAP3L | microfibrillar-associated protein 3-like |
MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
MRPL41 | mitochondrial ribosomal protein L41 |
MST1 | macrophage stimulating 1 |
MYOZ1 | myozenin 1 |
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
NOV | nephroblastoma overexpressed |
PEX3 | peroxisomal biogenesis factor 3 |
PHC3 | polyhomeotic homolog 3 (Drosophila) |
PHF7 | PHD finger protein 7 |
PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
PNMAL1 | paraneoplastic Ma antigen family-like 1 |
POPDC2 | popeye domain containing 2 |
PSG4 | pregnancy specific beta-1-glycoprotein 4 |
PTAFR | platelet-activating factor receptor |
RAB33A | RAB33A, member RAS oncogene family |
RNF122 | ring finger protein 122 |
ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SEC14L2 | SEC14-like 2 (S. cerevisiae) |
SELL | selectin L |
SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
SPTBN1 | spectrin, beta, non-erythrocytic 1 |
SPTBN5 | spectrin, beta, non-erythrocytic 5 |
SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
SVIL | supervillin |
TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
TBXA2R | thromboxane A2 receptor |
TRBC1 | T cell receptor beta constant 1 |
TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
TRPM1 | transient receptor potential cation channel, subfamily M, member 1 |
TULP1 | tubby like protein 1 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
USP46 | ubiquitin specific peptidase 46 |
WNT16 | wingless-type MMTV integration site family, member 16 |
WSCD1 | WSC domain containing 1 |
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
XAF1 | XIAP associated factor 1 |
YY2 | YY2 transcription factor |
Symbol | Name |
---|---|
ADTRP | androgen-dependent TFPI-regulating protein |
AHNAK2 | AHNAK nucleoprotein 2 |
ALPK1 | alpha-kinase 1 |
BAHCC1 | BAH domain and coiled-coil containing 1 |
BCORL1 | BCL6 corepressor-like 1 |
C11ORF30 | chromosome 11 open reading frame 30 |
C3 | complement component 3 |
CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
CAMK1 | calcium/calmodulin-dependent protein kinase I |
CCDC9 | coiled-coil domain containing 9 |
CDK18 | cyclin-dependent kinase 18 |
CDK3 | cyclin-dependent kinase 3 |
CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
CENPO | centromere protein O |
CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
CHST10 | carbohydrate sulfotransferase 10 |
CNR2 | cannabinoid receptor 2 (macrophage) |
CRIP1 | cysteine-rich protein 1 (intestinal) |
DBF4B | DBF4 zinc finger B |
DEAF1 | DEAF1 transcription factor |
DNM3 | dynamin 3 |
DTX2 | deltex 2, E3 ubiquitin ligase |
EDAR | ectodysplasin A receptor |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
ELMO3 | engulfment and cell motility 3 |
ETV6 | ets variant 6 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FAM131A | family with sequence similarity 131, member A |
FAM53B | family with sequence similarity 53, member B |
FBXO22 | F-box protein 22 |
FCHSD2 | FCH and double SH3 domains 2 |
FOXI1 | forkhead box I1 |
GADD45G | growth arrest and DNA-damage-inducible, gamma |
GBP2 | guanylate binding protein 2, interferon-inducible |
GPR143 | G protein-coupled receptor 143 |
GPR21 | G protein-coupled receptor 21 |
GRAMD1C | GRAM domain containing 1C |
GRTP1 | growth hormone regulated TBC protein 1 |
HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
HIST1H2AL | histone cluster 1, H2al |
HIST1H4A | histone cluster 1, H4a |
HYAL1 | hyaluronoglucosaminidase 1 |
INHA | inhibin, alpha |
IRX4 | iroquois homeobox 4 |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
JUNB | jun B proto-oncogene |
KIAA0355 | KIAA0355 |
KRT83 | keratin 83, type II |
LHX1 | LIM homeobox 1 |
LOXL3 | lysyl oxidase-like 3 |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
MAGEA5 | melanoma antigen family A5 |
MAPK10 | mitogen-activated protein kinase 10 |
MATK | megakaryocyte-associated tyrosine kinase |
MTCP1 | mature T-cell proliferation 1 |
MYO1D | myosin ID |
NOL10 | nucleolar protein 10 |
ONECUT2 | one cut homeobox 2 |
OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
PDIA3 | protein disulfide isomerase family A, member 3 |
PHF14 | PHD finger protein 14 |
POLM | polymerase (DNA directed), mu |
POM121 | POM121 transmembrane nucleoporin |
PRKCE | protein kinase C, epsilon |
RANBP17 | RAN binding protein 17 |
RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
RIC8B | RIC8 guanine nucleotide exchange factor B |
RNF39 | ring finger protein 39 |
RPAP2 | RNA polymerase II associated protein 2 |
RPL10L | ribosomal protein L10-like |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SECTM1 | secreted and transmembrane 1 |
SLC12A9 | solute carrier family 12, member 9 |
SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
SLMO1 | slowmo homolog 1 (Drosophila) |
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
STRA6 | stimulated by retinoic acid 6 |
TAOK1 | TAO kinase 1 |
TBC1D19 | TBC1 domain family, member 19 |
TBC1D2 | TBC1 domain family, member 2 |
THRAP3 | thyroid hormone receptor associated protein 3 |
TLR5 | toll-like receptor 5 |
TMEM53 | transmembrane protein 53 |
TMPRSS4 | transmembrane protease, serine 4 |
TRAF3IP1 | TNF receptor-associated factor 3 interacting protein 1 |
TRIM68 | tripartite motif containing 68 |
TTC23 | tetratricopeptide repeat domain 23 |
VGF | VGF nerve growth factor inducible |
VPS9D1 | VPS9 domain containing 1 |
WDR25 | WD repeat domain 25 |
WDR78 | WD repeat domain 78 |
WDR82 | WD repeat domain 82 |
ZBTB48 | zinc finger and BTB domain containing 48 |
ZBTB6 | zinc finger and BTB domain containing 6 |
ZFHX2 | zinc finger homeobox 2 |
ZNF141 | zinc finger protein 141 |
ZNF532 | zinc finger protein 532 |