nifedipine-1692 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the nifedipine-1692 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ACVR1B activin A receptor, type IB
ADD2 adducin 2 (beta)
AIF1 allograft inflammatory factor 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARL4C ADP-ribosylation factor-like 4C
ATG10 autophagy related 10
ATP11A ATPase, class VI, type 11A
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
C19ORF73 chromosome 19 open reading frame 73
C21ORF2 chromosome 21 open reading frame 2
C2ORF44 chromosome 2 open reading frame 44
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD1A CD1a molecule
CNGB3 cyclic nucleotide gated channel beta 3
CNOT4 CCR4-NOT transcription complex, subunit 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCR4 chemokine (C-X-C motif) receptor 4
DCAKD dephospho-CoA kinase domain containing
DGAT1 diacylglycerol O-acyltransferase 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
EDRF1 erythroid differentiation regulatory factor 1
EGR1 early growth response 1
EPX eosinophil peroxidase
FAM188A family with sequence similarity 188, member A
FCF1 FCF1 rRNA-processing protein
FOSL1 FOS-like antigen 1
FOXG1 forkhead box G1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GBP1 guanylate binding protein 1, interferon-inducible
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HMOX1 heme oxygenase 1
HPS1 Hermansky-Pudlak syndrome 1
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IRF6 interferon regulatory factor 6
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KDM4C lysine (K)-specific demethylase 4C
KREMEN2 kringle containing transmembrane protein 2
KRT17 keratin 17, type I
LIME1 Lck interacting transmembrane adaptor 1
LMAN1 lectin, mannose-binding, 1
LPP LIM domain containing preferred translocation partner in lipoma
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCOA2 nuclear receptor coactivator 2
NEUROD4 neuronal differentiation 4
NF2 neurofibromin 2 (merlin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OSMR oncostatin M receptor
PAIP2B poly(A) binding protein interacting protein 2B
PIDD1 p53-induced death domain protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PML promyelocytic leukemia
POLH polymerase (DNA directed), eta
POMT2 protein-O-mannosyltransferase 2
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRDM2 PR domain containing 2, with ZNF domain
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PVT1 Pvt1 oncogene (non-protein coding)
RAB28 RAB28, member RAS oncogene family
RBL2 retinoblastoma-like 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF208 ring finger protein 208
SGSM3 small G protein signaling modulator 3
SIM2 single-minded family bHLH transcription factor 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC43A3 solute carrier family 43, member 3
SMAD3 SMAD family member 3
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNTA1 syntrophin, alpha 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TBX10 T-box 10
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TP53I11 tumor protein p53 inducible protein 11
VCX2 variable charge, X-linked 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB1 zinc finger and BTB domain containing 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZFR zinc finger RNA binding protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF134 zinc finger protein 134
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ANKRD36 ankyrin repeat domain 36
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BAK1 BCL2-antagonist/killer 1
BCORL1 BCL6 corepressor-like 1
C16ORF59 chromosome 16 open reading frame 59
C9ORF40 chromosome 9 open reading frame 40
CAPRIN2 caprin family member 2
CCDC9 coiled-coil domain containing 9
CDK20 cyclin-dependent kinase 20
CFAP44 cilia and flagella associated protein 44
CHKA choline kinase alpha
CHKB choline kinase beta
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CLASP1 cytoplasmic linker associated protein 1
CLDN15 claudin 15
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRABP1 cellular retinoic acid binding protein 1
DACH1 dachshund family transcription factor 1
DCLRE1A DNA cross-link repair 1A
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOCK1 dedicator of cytokinesis 1
DVL1 dishevelled segment polarity protein 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EVPL envoplakin
EXOSC9 exosome component 9
FAM53B family with sequence similarity 53, member B
FBXO22 F-box protein 22
FERMT1 fermitin family member 1
FLJ22184
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GUSBP3 glucuronidase, beta pseudogene 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM5C lysine (K)-specific demethylase 5C
KLHL36 kelch-like family member 36
LAMB3 laminin, beta 3
LIG4 ligase IV, DNA, ATP-dependent
LOC730101 uncharacterized LOC730101
MANBA mannosidase, beta A, lysosomal
MID1IP1 MID1 interacting protein 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NBEAL2 neurobeachin-like 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
NXN nucleoredoxin
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PGP phosphoglycolate phosphatase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD3 phospholipase D family, member 3
PNPLA6 patatin-like phospholipase domain containing 6
RAB4B RAB4B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
REEP4 receptor accessory protein 4
RNFT2 ring finger protein, transmembrane 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SH2B3 SH2B adaptor protein 3
SHPK sedoheptulokinase
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC46A3 solute carrier family 46, member 3
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMYD3 SET and MYND domain containing 3
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYCP2 synaptonemal complex protein 2
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM62 transmembrane protein 62
TPRA1 transmembrane protein, adipocyte asscociated 1
TTC33 tetratricopeptide repeat domain 33
TUBA3D tubulin, alpha 3d
UNC119 unc-119 homolog (C. elegans)
VAV1 vav 1 guanine nucleotide exchange factor
WBP2 WW domain binding protein 2
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED1 zinc finger, BED-type containing 1
ZBTB25 zinc finger and BTB domain containing 25
ZNF184 zinc finger protein 184
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF586 zinc finger protein 586
ZSCAN31 zinc finger and SCAN domain containing 31